487 related articles for article (PubMed ID: 29945974)
21. Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36.
Poulin MB; Schneck JL; Matico RE; McDevitt PJ; Huddleston MJ; Hou W; Johnson NW; Thrall SH; Meek TD; Schramm VL
Proc Natl Acad Sci U S A; 2016 Feb; 113(5):1197-201. PubMed ID: 26787850
[TBL] [Abstract][Full Text] [Related]
22. The NSD2/WHSC1/MMSET methyltransferase prevents cellular senescence-associated epigenomic remodeling.
Tanaka H; Igata T; Etoh K; Koga T; Takebayashi SI; Nakao M
Aging Cell; 2020 Jul; 19(7):e13173. PubMed ID: 32573059
[TBL] [Abstract][Full Text] [Related]
23. Inhibition of Nuclear Receptor Binding SET Domain 2/Multiple Myeloma SET Domain by LEM-06 Implication for Epigenetic Cancer Therapies.
di Luccio E
J Cancer Prev; 2015 Jun; 20(2):113-20. PubMed ID: 26151044
[TBL] [Abstract][Full Text] [Related]
24. A Basic Post-SET Extension of NSDs Is Essential for Nucleosome Binding In Vitro.
Allali-Hassani A; Kuznetsova E; Hajian T; Wu H; Dombrovski L; Li Y; Gräslund S; Arrowsmith CH; Schapira M; Vedadi M
J Biomol Screen; 2014 Jul; 19(6):928-35. PubMed ID: 24595546
[TBL] [Abstract][Full Text] [Related]
25. Recent advances in nuclear receptor-binding SET domain 2 (NSD2) inhibitors: An update and perspectives.
Zhang L; Zha X
Eur J Med Chem; 2023 Mar; 250():115232. PubMed ID: 36863225
[TBL] [Abstract][Full Text] [Related]
26. NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming.
Kuo AJ; Cheung P; Chen K; Zee BM; Kioi M; Lauring J; Xi Y; Park BH; Shi X; Garcia BA; Li W; Gozani O
Mol Cell; 2011 Nov; 44(4):609-20. PubMed ID: 22099308
[TBL] [Abstract][Full Text] [Related]
27. NSD2 is recruited through its PHD domain to oncogenic gene loci to drive multiple myeloma.
Huang Z; Wu H; Chuai S; Xu F; Yan F; Englund N; Wang Z; Zhang H; Fang M; Wang Y; Gu J; Zhang M; Yang T; Zhao K; Yu Y; Dai J; Yi W; Zhou S; Li Q; Wu J; Liu J; Wu X; Chan H; Lu C; Atadja P; Li E; Wang Y; Hu M
Cancer Res; 2013 Oct; 73(20):6277-88. PubMed ID: 23980095
[TBL] [Abstract][Full Text] [Related]
28. Cancers and the NSD family of histone lysine methyltransferases.
Morishita M; di Luccio E
Biochim Biophys Acta; 2011 Dec; 1816(2):158-63. PubMed ID: 21664949
[TBL] [Abstract][Full Text] [Related]
29. Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives.
Tisi D; Chiarparin E; Tamanini E; Pathuri P; Coyle JE; Hold A; Holding FP; Amin N; Martin AC; Rich SJ; Berdini V; Yon J; Acklam P; Burke R; Drouin L; Harmer JE; Jeganathan F; van Montfort RL; Newbatt Y; Tortorici M; Westlake M; Wood A; Hoelder S; Heightman TD
ACS Chem Biol; 2016 Nov; 11(11):3093-3105. PubMed ID: 27571355
[TBL] [Abstract][Full Text] [Related]
30. Discovery of novel small molecule inhibitors of lysine methyltransferase G9a and their mechanism in leukemia cell lines.
Kondengaden SM; Luo LF; Huang K; Zhu M; Zang L; Bataba E; Wang R; Luo C; Wang B; Li KK; Wang PG
Eur J Med Chem; 2016 Oct; 122():382-393. PubMed ID: 27393948
[TBL] [Abstract][Full Text] [Related]
31. PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by
Li J; Hlavka-Zhang J; Shrimp JH; Piper C; Dupéré-Richér D; Roth JS; Jing D; Casellas Román HL; Troche C; Swaroop A; Kulis M; Oyer JA; Will CM; Shen M; Riva A; Bennett RL; Ferrando AA; Hall MD; Lock RB; Licht JD
Cancer Discov; 2022 Jan; 12(1):186-203. PubMed ID: 34417224
[TBL] [Abstract][Full Text] [Related]
32. Efficient hit-finding approaches for histone methyltransferases: the key parameters.
Ahrens T; Bergner A; Sheppard D; Hafenbradl D
J Biomol Screen; 2012 Jan; 17(1):85-98. PubMed ID: 21990582
[TBL] [Abstract][Full Text] [Related]
33. NMR backbone resonance assignment and solution secondary structure determination of human NSD1 and NSD2.
Amin N; Nietlispach D; Qamar S; Coyle J; Chiarparin E; Williams G
Biomol NMR Assign; 2016 Oct; 10(2):315-20. PubMed ID: 27356987
[TBL] [Abstract][Full Text] [Related]
34. Identification of a peptide inhibitor for the histone methyltransferase WHSC1.
Morrison MJ; Boriack-Sjodin PA; Swinger KK; Wigle TJ; Sadalge D; Kuntz KW; Scott MP; Janzen WP; Chesworth R; Duncan KW; Harvey DM; Lampe JW; Mitchell LH; Copeland RA
PLoS One; 2018; 13(5):e0197082. PubMed ID: 29742153
[TBL] [Abstract][Full Text] [Related]
35. A High-Throughput Dose-Response Cellular Thermal Shift Assay for Rapid Screening of Drug Target Engagement in Living Cells, Exemplified Using SMYD3 and IDO1.
McNulty DE; Bonnette WG; Qi H; Wang L; Ho TF; Waszkiewicz A; Kallal LA; Nagarajan RP; Stern M; Quinn AM; Creasy CL; Su DS; Graves AP; Annan RS; Sweitzer SM; Holbert MA
SLAS Discov; 2018 Jan; 23(1):34-46. PubMed ID: 28957646
[TBL] [Abstract][Full Text] [Related]
36. A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization.
Dilworth D; Hanley RP; Ferreira de Freitas R; Allali-Hassani A; Zhou M; Mehta N; Marunde MR; Ackloo S; Carvalho Machado RA; Khalili Yazdi A; Owens DDG; Vu V; Nie DY; Alqazzaz M; Marcon E; Li F; Chau I; Bolotokova A; Qin S; Lei M; Liu Y; Szewczyk MM; Dong A; Kazemzadeh S; Abramyan T; Popova IK; Hall NW; Meiners MJ; Cheek MA; Gibson E; Kireev D; Greenblatt JF; Keogh MC; Min J; Brown PJ; Vedadi M; Arrowsmith CH; Barsyte-Lovejoy D; James LI; Schapira M
Nat Chem Biol; 2022 Jan; 18(1):56-63. PubMed ID: 34782742
[TBL] [Abstract][Full Text] [Related]
37. The catalytic domain of the histone methyltransferase NSD2/MMSET is required for the generation of B1 cells in mice.
Dobenecker MW; Marcello J; Becker A; Rudensky E; Bhanu NV; Carrol T; Garcia BA; Prinjha R; Yurchenko V; Tarakhovsky A
FEBS Lett; 2020 Oct; 594(20):3324-3337. PubMed ID: 32862441
[TBL] [Abstract][Full Text] [Related]
38. A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin.
Sankaran SM; Wilkinson AW; Elias JE; Gozani O
J Biol Chem; 2016 Apr; 291(16):8465-74. PubMed ID: 26912663
[TBL] [Abstract][Full Text] [Related]
39. A direct label-free MALDI-TOF mass spectrometry based assay for the characterization of inhibitors of protein lysine methyltransferases.
Guitot K; Drujon T; Burlina F; Sagan S; Beaupierre S; Pamlard O; Dodd RH; Guillou C; Bolbach G; Sachon E; Guianvarc'h D
Anal Bioanal Chem; 2017 Jun; 409(15):3767-3777. PubMed ID: 28389916
[TBL] [Abstract][Full Text] [Related]
40. Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
Clausse V; Tao D; Debnath S; Fang Y; Tagad HD; Wang Y; Sun H; LeClair CA; Mazur SJ; Lane K; Shi ZD; Vasalatiy O; Eells R; Baker LK; Henderson MJ; Webb MR; Shen M; Hall MD; Appella E; Appella DH; Coussens NP
J Biol Chem; 2019 Nov; 294(46):17654-17668. PubMed ID: 31481464
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
