These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

495 related articles for article (PubMed ID: 29950720)

  • 1. OTULIN limits cell death and inflammation by deubiquitinating LUBAC.
    Heger K; Wickliffe KE; Ndoja A; Zhang J; Murthy A; Dugger DL; Maltzman A; de Sousa E Melo F; Hung J; Zeng Y; Verschueren E; Kirkpatrick DS; Vucic D; Lee WP; Roose-Girma M; Newman RJ; Warming S; Hsiao YC; Kőműves LG; Webster JD; Newton K; Dixit VM
    Nature; 2018 Jul; 559(7712):120-124. PubMed ID: 29950720
    [TBL] [Abstract][Full Text] [Related]  

  • 2. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.
    Peltzer N; Darding M; Montinaro A; Draber P; Draberova H; Kupka S; Rieser E; Fisher A; Hutchinson C; Taraborrelli L; Hartwig T; Lafont E; Haas TL; Shimizu Y; Böiers C; Sarr A; Rickard J; Alvarez-Diaz S; Ashworth MT; Beal A; Enver T; Bertin J; Kaiser W; Strasser A; Silke J; Bouillet P; Walczak H
    Nature; 2018 May; 557(7703):112-117. PubMed ID: 29695863
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reciprocal interplay between OTULIN-LUBAC determines genotoxic and inflammatory NF-κB signal responses.
    Li M; Li L; Asemota S; Kakhniashvili D; Narayanan R; Wang X; Liao FF
    Proc Natl Acad Sci U S A; 2022 Aug; 119(33):e2123097119. PubMed ID: 35939695
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death.
    Douglas T; Saleh M
    Cell Rep; 2019 Dec; 29(11):3652-3663.e5. PubMed ID: 31825842
    [TBL] [Abstract][Full Text] [Related]  

  • 5. LUBAC and OTULIN regulate autophagy initiation and maturation by mediating the linear ubiquitination and the stabilization of ATG13.
    Chu Y; Kang Y; Yan C; Yang C; Zhang T; Huo H; Liu Y
    Autophagy; 2021 Jul; 17(7):1684-1699. PubMed ID: 32543267
    [TBL] [Abstract][Full Text] [Related]  

  • 6. OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice.
    Schünke H; Göbel U; Dikic I; Pasparakis M
    Nat Commun; 2021 Oct; 12(1):5912. PubMed ID: 34625557
    [TBL] [Abstract][Full Text] [Related]  

  • 7. OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity.
    Hoste E; Lecomte K; Annusver K; Vandamme N; Roels J; Maschalidi S; Verboom L; Vikkula HK; Sze M; Van Hove L; Verstaen K; Martens A; Hochepied T; Saeys Y; Ravichandran K; Kasper M; van Loo G
    Nat Commun; 2021 Oct; 12(1):5913. PubMed ID: 34625556
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN.
    Takiuchi T; Nakagawa T; Tamiya H; Fujita H; Sasaki Y; Saeki Y; Takeda H; Sawasaki T; Buchberger A; Kimura T; Iwai K
    Genes Cells; 2014 Mar; 19(3):254-72. PubMed ID: 24461064
    [TBL] [Abstract][Full Text] [Related]  

  • 9. OTULIN deficiency in ORAS causes cell type-specific LUBAC degradation, dysregulated TNF signalling and cell death.
    Damgaard RB; Elliott PR; Swatek KN; Maher ER; Stepensky P; Elpeleg O; Komander D; Berkun Y
    EMBO Mol Med; 2019 Mar; 11(3):. PubMed ID: 30804083
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dominant negative OTULIN-related autoinflammatory syndrome.
    Davidson S; Shibata Y; Collard S; Zheng H; Kong K; Sun JM; Laohamonthonkul P; Cerra A; Kratina T; ; ; Li MWY; Russell C; van Beek A; Kirk EP; Walsh R; Alqanatish J; Almojali A; Alsuwairi W; Alrasheed A; Lalaoui N; Gray PE; Komander D; Masters SL
    J Exp Med; 2024 Jun; 221(6):. PubMed ID: 38630025
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RIPK1 inhibits ZBP1-driven necroptosis during development.
    Newton K; Wickliffe KE; Maltzman A; Dugger DL; Strasser A; Pham VC; Lill JR; Roose-Girma M; Warming S; Solon M; Ngu H; Webster JD; Dixit VM
    Nature; 2016 Dec; 540(7631):129-133. PubMed ID: 27819682
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
    Damgaard RB; Walker JA; Marco-Casanova P; Morgan NV; Titheradge HL; Elliott PR; McHale D; Maher ER; McKenzie ANJ; Komander D
    Cell; 2016 Aug; 166(5):1215-1230.e20. PubMed ID: 27523608
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death.
    Kist M; Kőműves LG; Goncharov T; Dugger DL; Yu C; Roose-Girma M; Newton K; Webster JD; Vucic D
    Cell Death Differ; 2021 Mar; 28(3):985-1000. PubMed ID: 32999468
    [TBL] [Abstract][Full Text] [Related]  

  • 14. OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis.
    Verboom L; Martens A; Priem D; Hoste E; Sze M; Vikkula H; Van Hove L; Voet S; Roels J; Maelfait J; Bongiovanni L; de Bruin A; Scott CL; Saeys Y; Pasparakis M; Bertrand MJM; van Loo G
    Cell Rep; 2020 Feb; 30(7):2237-2247.e6. PubMed ID: 32075762
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biochemistry, Pathophysiology, and Regulation of Linear Ubiquitination: Intricate Regulation by Coordinated Functions of the Associated Ligase and Deubiquitinase.
    Fuseya Y; Iwai K
    Cells; 2021 Oct; 10(10):. PubMed ID: 34685685
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ubiquitin-dependent and -independent functions of OTULIN in cell fate control and beyond.
    Weinelt N; van Wijk SJL
    Cell Death Differ; 2021 Feb; 28(2):493-504. PubMed ID: 33288901
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling.
    Hrdinka M; Fiil BK; Zucca M; Leske D; Bagola K; Yabal M; Elliott PR; Damgaard RB; Komander D; Jost PJ; Gyrd-Hansen M
    Cell Rep; 2016 Mar; 14(12):2846-58. PubMed ID: 26997266
    [TBL] [Abstract][Full Text] [Related]  

  • 18. OTULIN in NF-κB signaling, cell death, and disease.
    Verboom L; Hoste E; van Loo G
    Trends Immunol; 2021 Jul; 42(7):590-603. PubMed ID: 34074601
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Superimposed Deubiquitination Effect of OTULIN and Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Nsp11 Promotes Multiplication of PRRSV.
    Su Y; Shi P; Zhang L; Lu D; Zhao C; Li R; Zhang L; Huang J
    J Virol; 2018 May; 92(9):. PubMed ID: 29444948
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis.
    Newton K; Dugger DL; Wickliffe KE; Kapoor N; de Almagro MC; Vucic D; Komuves L; Ferrando RE; French DM; Webster J; Roose-Girma M; Warming S; Dixit VM
    Science; 2014 Mar; 343(6177):1357-60. PubMed ID: 24557836
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.