These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

324 related articles for article (PubMed ID: 29954749)

  • 1.
    Kahn JD; Miller PG; Silver AJ; Sellar RS; Bhatt S; Gibson C; McConkey M; Adams D; Mar B; Mertins P; Fereshetian S; Krug K; Zhu H; Letai A; Carr SA; Doench J; Jaiswal S; Ebert BL
    Blood; 2018 Sep; 132(11):1095-1105. PubMed ID: 29954749
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PPM1D in Solid and Hematologic Malignancies: Friend and Foe?
    Zhang L; Hsu JI; Goodell MA
    Mol Cancer Res; 2022 Sep; 20(9):1365-1378. PubMed ID: 35657598
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein phosphatase, Mg
    Husby S; Hjermind Justesen E; Grønbæk K
    Br J Haematol; 2021 Feb; 192(4):697-705. PubMed ID: 33616916
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting Mutant PPM1D Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib.
    Wang Z; Xu C; Diplas BH; Moure CJ; Chen CJ; Chen LH; Du C; Zhu H; Greer PK; Zhang L; He Y; Waitkus MS; Yan H
    Mol Cancer Res; 2020 Jul; 18(7):968-980. PubMed ID: 32229503
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Somatic mosaic truncating mutations of PPM1D in blood can result from expansion of a mutant clone under selective pressure of chemotherapy.
    Kim B; Won D; Lee ST; Choi JR
    PLoS One; 2019; 14(6):e0217521. PubMed ID: 31242196
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of mutant PPM1D enhances DNA damage response and growth suppressive effects of ionizing radiation in diffuse intrinsic pontine glioma.
    Akamandisa MP; Nie K; Nahta R; Hambardzumyan D; Castellino RC
    Neuro Oncol; 2019 Jun; 21(6):786-799. PubMed ID: 30852603
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy.
    Hsu JI; Dayaram T; Tovy A; De Braekeleer E; Jeong M; Wang F; Zhang J; Heffernan TP; Gera S; Kovacs JJ; Marszalek JR; Bristow C; Yan Y; Garcia-Manero G; Kantarjian H; Vassiliou G; Futreal PA; Donehower LA; Takahashi K; Goodell MA
    Cell Stem Cell; 2018 Nov; 23(5):700-713.e6. PubMed ID: 30388424
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state.
    Miller PG; Sathappa M; Moroco JA; Jiang W; Qian Y; Iqbal S; Guo Q; Giacomelli AO; Shaw S; Vernier C; Bajrami B; Yang X; Raffier C; Sperling AS; Gibson CJ; Kahn J; Jin C; Ranaghan M; Caliman A; Brousseau M; Fischer ES; Lintner R; Piccioni F; Campbell AJ; Root DE; Garvie CW; Ebert BL
    Nat Commun; 2022 Jun; 13(1):3778. PubMed ID: 35773251
    [TBL] [Abstract][Full Text] [Related]  

  • 9.
    Zhang L; Hsu JI; Braekeleer ED; Chen CW; Patel TD; Martell AG; Guzman AG; Wohlan K; Waldvogel SM; Uryu H; Tovy A; Callen E; Murdaugh RL; Richard R; Jansen S; Vissers L; de Vries BBA; Nussenzweig A; Huang S; Coarfa C; Anastas J; Takahashi K; Vassiliou G; Goodell MA
    Elife; 2024 Jun; 12():. PubMed ID: 38896450
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combination of lentivirus-mediated silencing of PPM1D and temozolomide chemotherapy eradicates malignant glioma through cell apoptosis and cell cycle arrest.
    Wang P; Ye JA; Hou CX; Zhou D; Zhan SQ
    Oncol Rep; 2016 Nov; 36(5):2544-2552. PubMed ID: 27633132
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chemical Inhibition of Wild-Type p53-Induced Phosphatase 1 (WIP1/PPM1D) by GSK2830371 Potentiates the Sensitivity to MDM2 Inhibitors in a p53-Dependent Manner.
    Esfandiari A; Hawthorne TA; Nakjang S; Lunec J
    Mol Cancer Ther; 2016 Mar; 15(3):379-91. PubMed ID: 26832796
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon.
    Burocziova M; Burdova K; Martinikova AS; Kasparek P; Kleiblova P; Danielsen SA; Borecka M; Jenikova G; Janečková L; Pavel J; Zemankova P; Schneiderova M; Schwarzova L; Ticha I; Sun XF; Jiraskova K; Liska V; Vodickova L; Vodicka P; Sedlacek R; Kleibl Z; Lothe RA; Korinek V; Macurek L
    Cell Death Dis; 2019 Oct; 10(11):818. PubMed ID: 31659152
    [TBL] [Abstract][Full Text] [Related]  

  • 13. De Novo Truncating Mutations in the Last and Penultimate Exons of PPM1D Cause an Intellectual Disability Syndrome.
    Jansen S; Geuer S; Pfundt R; Brough R; Ghongane P; Herkert JC; Marco EJ; Willemsen MH; Kleefstra T; Hannibal M; Shieh JT; Lynch SA; Flinter F; FitzPatrick DR; Gardham A; Bernhard B; Ragge N; Newbury-Ecob R; Bernier R; Kvarnung M; Magnusson EA; Wessels MW; van Slegtenhorst MA; Monaghan KG; de Vries P; Veltman JA; ; Lord CJ; Vissers LE; de Vries BB
    Am J Hum Genet; 2017 Apr; 100(4):650-658. PubMed ID: 28343630
    [TBL] [Abstract][Full Text] [Related]  

  • 14. JAK2V617F mutant endothelial cells promote neoplastic hematopoiesis in a mixed vascular microenvironment.
    Mazzeo C; Quan M; Wong H; Castiglione M; Kaushansky K; Zhan H
    Blood Cells Mol Dis; 2021 Sep; 90():102585. PubMed ID: 34139651
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of Ser/Thr phosphatase PPM1D induces neutrophil differentiation in HL-60 cells.
    Kamada R; Kudoh F; Yoshimura F; Tanino K; Sakaguchi K
    J Biochem; 2017 Oct; 162(4):303-308. PubMed ID: 28486685
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Truncating mutations of PPM1D are found in blood DNA samples of lung cancer patients.
    Zajkowicz A; Butkiewicz D; Drosik A; Giglok M; Suwiński R; Rusin M
    Br J Cancer; 2015 Mar; 112(6):1114-20. PubMed ID: 25742468
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy.
    Miller PG; Sperling AS; Mayerhofer C; McConkey ME; Ellegast JM; Da Silva C; Cohen DN; Wang C; Sharda A; Yan N; Saha S; Schluter C; Schechter I; Słabicki M; Sandoval B; Kahn J; Boettcher S; Gibson CJ; Scadden DT; Stegmaier K; Bhatt S; Lindsley RC; Ebert BL
    Blood; 2023 Dec; 142(24):2079-2091. PubMed ID: 37595362
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3.
    Pechackova S; Burdova K; Benada J; Kleiblova P; Jenikova G; Macurek L
    Oncotarget; 2016 Mar; 7(12):14458-75. PubMed ID: 26883108
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutant
    Singh A; Mencia-Trinchant N; Griffiths EA; Altahan A; Swaminathan M; Gupta M; Gravina M; Tajammal R; Faber MG; Yan L; Sinha E; Hassane DC; Hayes DN; Guzman ML; Iyer R; Wang ES; Thota S
    JCO Precis Oncol; 2022 Jan; 6():e2100309. PubMed ID: 35025619
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma.
    Fons NR; Sundaram RK; Breuer GA; Peng S; McLean RL; Kalathil AN; Schmidt MS; Carvalho DM; Mackay A; Jones C; Carcaboso ÁM; Nazarian J; Berens ME; Brenner C; Bindra RS
    Nat Commun; 2019 Aug; 10(1):3790. PubMed ID: 31439867
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.