These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

86 related articles for article (PubMed ID: 29956673)

  • 1. Reshaping acetylated peptide selectivity between human BET Brd2 bromodomains BD-I and BD-II in glioblastoma by rationally grafting secondary anchor residues.
    Fei X; Wang A; Meng X; Wang Z
    Gen Physiol Biophys; 2018 Jul; 37(4):411-419. PubMed ID: 29956673
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Solution structure of the second bromodomain of Brd2 and its specific interaction with acetylated histone tails.
    Huang H; Zhang J; Shen W; Wang X; Wu J; Wu J; Shi Y
    BMC Struct Biol; 2007 Sep; 7():57. PubMed ID: 17848202
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure of the human BRD2 bromodomain: insights into dimerization and recognition of acetylated histone H4.
    Nakamura Y; Umehara T; Nakano K; Jang MK; Shirouzu M; Morita S; Uda-Tochio H; Hamana H; Terada T; Adachi N; Matsumoto T; Tanaka A; Horikoshi M; Ozato K; Padmanabhan B; Yokoyama S
    J Biol Chem; 2007 Feb; 282(6):4193-201. PubMed ID: 17148447
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis for acetylated histone H4 recognition by the human BRD2 bromodomain.
    Umehara T; Nakamura Y; Jang MK; Nakano K; Tanaka A; Ozato K; Padmanabhan B; Yokoyama S
    J Biol Chem; 2010 Mar; 285(10):7610-8. PubMed ID: 20048151
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural implications for K5/K12-di-acetylated histone H4 recognition by the second bromodomain of BRD2.
    Umehara T; Nakamura Y; Wakamori M; Ozato K; Yokoyama S; Padmanabhan B
    FEBS Lett; 2010 Sep; 584(18):3901-8. PubMed ID: 20709061
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular design of Stat3-derived peptide selectivity between BET proteins Brd2 and Brd4 in ovarian cancer.
    Zhu L; Ding X
    J Mol Recognit; 2018 Feb; 31(2):. PubMed ID: 28983974
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of Tetrahydroquinoxalines as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the Second Bromodomain.
    Law RP; Atkinson SJ; Bamborough P; Chung CW; Demont EH; Gordon LJ; Lindon M; Prinjha RK; Watson AJB; Hirst DJ
    J Med Chem; 2018 May; 61(10):4317-4334. PubMed ID: 29656650
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery and characterization of small molecule inhibitors of the BET family bromodomains.
    Chung CW; Coste H; White JH; Mirguet O; Wilde J; Gosmini RL; Delves C; Magny SM; Woodward R; Hughes SA; Boursier EV; Flynn H; Bouillot AM; Bamborough P; Brusq JM; Gellibert FJ; Jones EJ; Riou AM; Homes P; Martin SL; Uings IJ; Toum J; Clement CA; Boullay AB; Grimley RL; Blandel FM; Prinjha RK; Lee K; Kirilovsky J; Nicodeme E
    J Med Chem; 2011 Jun; 54(11):3827-38. PubMed ID: 21568322
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selective inhibition mechanism of RVX-208 to the second bromodomain of bromo and extraterminal proteins: insight from microsecond molecular dynamics simulations.
    Wang Q; Li Y; Xu J; Wang Y; Leung EL; Liu L; Yao X
    Sci Rep; 2017 Aug; 7(1):8857. PubMed ID: 28821780
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous Proteins.
    Taniguchi Y
    Int J Mol Sci; 2016 Nov; 17(11):. PubMed ID: 27827996
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of ZA channel water-mediated interactions in the design of bromodomain-selective BET inhibitors.
    Bharatham N; Slavish PJ; Shadrick WR; Young BM; Shelat AA
    J Mol Graph Model; 2018 May; 81():197-210. PubMed ID: 29605436
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective recognition of acetylated histones by bromodomains in transcriptional co-activators.
    Hassan AH; Awad S; Al-Natour Z; Othman S; Mustafa F; Rizvi TA
    Biochem J; 2007 Feb; 402(1):125-33. PubMed ID: 17049045
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A bromodomain-DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT.
    Miller TC; Simon B; Rybin V; Grötsch H; Curtet S; Khochbin S; Carlomagno T; Müller CW
    Nat Commun; 2016 Dec; 7():13855. PubMed ID: 27991587
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Spatially restricted loading of BRD2 at DNA double-strand breaks protects H4 acetylation domains and promotes DNA repair.
    Gursoy-Yuzugullu O; Carman C; Price BD
    Sci Rep; 2017 Oct; 7(1):12921. PubMed ID: 29018219
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Solution structure and acetyl-lysine binding activity of the GCN5 bromodomain.
    Hudson BP; Martinez-Yamout MA; Dyson HJ; Wright PE
    J Mol Biol; 2000 Dec; 304(3):355-70. PubMed ID: 11090279
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective targeting of MAPK family kinases JNK over p38 by rationally designed peptides as potential therapeutics for neurological disorders and epilepsy.
    Zhuo ZH; Sun YZ; Jin PN; Li FY; Zhang YL; Wang HL
    Mol Biosyst; 2016 Jul; 12(8):2532-40. PubMed ID: 27263470
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural ramification for acetyl-lysine recognition by the bromodomain of human BRG1 protein, a central ATPase of the SWI/SNF remodeling complex.
    Singh M; Popowicz GM; Krajewski M; Holak TA
    Chembiochem; 2007 Jul; 8(11):1308-16. PubMed ID: 17582821
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Novel Phenanthridionone Based Scaffold As a Potential Inhibitor of the BRD2 Bromodomain: Crystal Structure of the Complex.
    Tripathi S; Mathur S; Deshmukh P; Manjula R; Padmanabhan B
    PLoS One; 2016; 11(5):e0156344. PubMed ID: 27243809
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RVX-297- a novel BD2 selective inhibitor of BET bromodomains.
    Kharenko OA; Gesner EM; Patel RG; Norek K; White A; Fontano E; Suto RK; Young PR; McLure KG; Hansen HC
    Biochem Biophys Res Commun; 2016 Aug; 477(1):62-67. PubMed ID: 27282480
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selective recognition of acetylated histones by bromodomain proteins visualized in living cells.
    Kanno T; Kanno Y; Siegel RM; Jang MK; Lenardo MJ; Ozato K
    Mol Cell; 2004 Jan; 13(1):33-43. PubMed ID: 14731392
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.