BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

254 related articles for article (PubMed ID: 29965747)

  • 1. A Radical Clock Probe Uncouples H Atom Abstraction from Thioether Cross-Link Formation by the Radical S-Adenosyl-l-methionine Enzyme SkfB.
    Kincannon WM; Bruender NA; Bandarian V
    Biochemistry; 2018 Aug; 57(32):4816-4823. PubMed ID: 29965747
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SkfB Abstracts a Hydrogen Atom from Cα on SkfA To Initiate Thioether Cross-Link Formation.
    Bruender NA; Bandarian V
    Biochemistry; 2016 Aug; 55(30):4131-4. PubMed ID: 27410522
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural and spectroscopic analyses of the sporulation killing factor biosynthetic enzyme SkfB, a bacterial AdoMet radical sactisynthase.
    Grell TAJ; Kincannon WM; Bruender NA; Blaesi EJ; Krebs C; Bandarian V; Drennan CL
    J Biol Chem; 2018 Nov; 293(45):17349-17361. PubMed ID: 30217813
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Two [4Fe-4S] clusters containing radical SAM enzyme SkfB catalyze thioether bond formation during the maturation of the sporulation killing factor.
    Flühe L; Burghaus O; Wieckowski BM; Giessen TW; Linne U; Marahiel MA
    J Am Chem Soc; 2013 Jan; 135(3):959-62. PubMed ID: 23282011
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Peptide Selenocysteine Substitutions Reveal Direct Substrate-Enzyme Interactions at Auxiliary Clusters in Radical
    Rush KW; Eastman KAS; Kincannon WM; Blackburn NJ; Bandarian V
    J Am Chem Soc; 2023 May; 145(18):10167-10177. PubMed ID: 37104670
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pyruvate formate-lyase activating enzyme: The catalytically active 5'-deoxyadenosyl radical caught in the act of H-atom abstraction.
    Lundahl MN; Yang H; Broderick WE; Hoffman BM; Broderick JB
    Proc Natl Acad Sci U S A; 2023 Nov; 120(47):e2314696120. PubMed ID: 37956301
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biochemical and Spectroscopic Characterization of a Radical S-Adenosyl-L-methionine Enzyme Involved in the Formation of a Peptide Thioether Cross-Link.
    Bruender NA; Wilcoxen J; Britt RD; Bandarian V
    Biochemistry; 2016 Apr; 55(14):2122-34. PubMed ID: 27007615
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Post-translational modification of ribosomally synthesized peptides by a radical SAM epimerase in Bacillus subtilis.
    Benjdia A; Guillot A; Ruffié P; Leprince J; Berteau O
    Nat Chem; 2017 Jul; 9(7):698-707. PubMed ID: 28644475
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biosynthesis of the sactipeptide Ruminococcin C by the human microbiome: Mechanistic insights into thioether bond formation by radical SAM enzymes.
    Balty C; Guillot A; Fradale L; Brewee C; Lefranc B; Herrero C; Sandström C; Leprince J; Berteau O; Benjdia A
    J Biol Chem; 2020 Dec; 295(49):16665-16677. PubMed ID: 32972973
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Leveraging Substrate Promiscuity of a Radical
    Eastman KAS; Kincannon WM; Bandarian V
    ACS Cent Sci; 2022 Aug; 8(8):1209-1217. PubMed ID: 36032765
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expanding Radical SAM Chemistry by Using Radical Addition Reactions and SAM Analogues.
    Ji X; Li Y; Xie L; Lu H; Ding W; Zhang Q
    Angew Chem Int Ed Engl; 2016 Sep; 55(39):11845-8. PubMed ID: 27573794
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Radical SAM enzymes in methylation and methylthiolation.
    Hutcheson RU; Broderick JB
    Metallomics; 2012 Nov; 4(11):1149-54. PubMed ID: 22992596
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Trapping and Electron Paramagnetic Resonance Characterization of the 5'dAdo
    Sayler RI; Stich TA; Joshi S; Cooper N; Shaw JT; Begley TP; Tantillo DJ; Britt RD
    ACS Cent Sci; 2019 Nov; 5(11):1777-1785. PubMed ID: 31807679
    [No Abstract]   [Full Text] [Related]  

  • 14. Auxiliary iron-sulfur cofactors in radical SAM enzymes.
    Lanz ND; Booker SJ
    Biochim Biophys Acta; 2015 Jun; 1853(6):1316-34. PubMed ID: 25597998
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Radical SAM catalysis via an organometallic intermediate with an Fe-[5'-C]-deoxyadenosyl bond.
    Horitani M; Shisler K; Broderick WE; Hutcheson RU; Duschene KS; Marts AR; Hoffman BM; Broderick JB
    Science; 2016 May; 352(6287):822-5. PubMed ID: 27174986
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Direct Detection of the α-Carbon Radical Intermediate Formed by OspD: Mechanistic Insights into Radical
    Walls WG; Vagstad AL; Delridge T; Piel J; Broderick WE; Broderick JB
    J Am Chem Soc; 2024 Feb; 146(8):5550-5559. PubMed ID: 38364824
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Paradigm Shift for Radical S-Adenosyl-l-methionine Reactions: The Organometallic Intermediate Ω Is Central to Catalysis.
    Byer AS; Yang H; McDaniel EC; Kathiresan V; Impano S; Pagnier A; Watts H; Denler C; Vagstad AL; Piel J; Duschene KS; Shepard EM; Shields TP; Scott LG; Lilla EA; Yokoyama K; Broderick WE; Hoffman BM; Broderick JB
    J Am Chem Soc; 2018 Jul; 140(28):8634-8638. PubMed ID: 29954180
    [TBL] [Abstract][Full Text] [Related]  

  • 18.
    Lundahl MN; Sarksian R; Yang H; Jodts RJ; Pagnier A; Smith DF; Mosquera MA; van der Donk WA; Hoffman BM; Broderick WE; Broderick JB
    J Am Chem Soc; 2022 Mar; 144(11):5087-5098. PubMed ID: 35258967
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deconvoluting the Reduction Potentials for the Three [4Fe-4S] Clusters in an AdoMet Radical SCIFF Maturase.
    Walker LM; Kincannon WM; Bandarian V; Elliott SJ
    Biochemistry; 2018 Oct; 57(42):6050-6053. PubMed ID: 30272955
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanistic study on the reaction of a radical SAM dehydrogenase BtrN by electron paramagnetic resonance spectroscopy.
    Yokoyama K; Ohmori D; Kudo F; Eguchi T
    Biochemistry; 2008 Aug; 47(34):8950-60. PubMed ID: 18672902
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.