BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

421 related articles for article (PubMed ID: 29967261)

  • 1. CRISPR/Cas9-Mediated Knockout of DGK Improves Antitumor Activities of Human T Cells.
    Jung IY; Kim YY; Yu HS; Lee M; Kim S; Lee J
    Cancer Res; 2018 Aug; 78(16):4692-4703. PubMed ID: 29967261
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TCR signaling intensity controls CD8+ T cell responsiveness to TGF-β.
    Arumugam V; Bluemn T; Wesley E; Schmidt AM; Kambayashi T; Malarkannan S; Riese MJ
    J Leukoc Biol; 2015 Nov; 98(5):703-12. PubMed ID: 26153417
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhanced Cancer Immunotherapy by Chimeric Antigen Receptor-Modified T Cells Engineered to Secrete Checkpoint Inhibitors.
    Li S; Siriwon N; Zhang X; Yang S; Jin T; He F; Kim YJ; Mac J; Lu Z; Wang S; Han X; Wang P
    Clin Cancer Res; 2017 Nov; 23(22):6982-6992. PubMed ID: 28912137
    [No Abstract]   [Full Text] [Related]  

  • 4. Enhanced effector responses in activated CD8+ T cells deficient in diacylglycerol kinases.
    Riese MJ; Wang LC; Moon EK; Joshi RP; Ranganathan A; June CH; Koretzky GA; Albelda SM
    Cancer Res; 2013 Jun; 73(12):3566-77. PubMed ID: 23576561
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nucleofection with Plasmid DNA for CRISPR/Cas9-Mediated Inactivation of Programmed Cell Death Protein 1 in CD133-Specific CAR T Cells.
    Hu B; Zou Y; Zhang L; Tang J; Niedermann G; Firat E; Huang X; Zhu X
    Hum Gene Ther; 2019 Apr; 30(4):446-458. PubMed ID: 29706119
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel chimeric antigen receptor containing a JAK-STAT signaling domain mediates superior antitumor effects.
    Kagoya Y; Tanaka S; Guo T; Anczurowski M; Wang CH; Saso K; Butler MO; Minden MD; Hirano N
    Nat Med; 2018 Mar; 24(3):352-359. PubMed ID: 29400710
    [TBL] [Abstract][Full Text] [Related]  

  • 7. T cell activation in vivo targets diacylglycerol kinase alpha to the membrane: a novel mechanism for Ras attenuation.
    Sanjuán MA; Pradet-Balade B; Jones DR; Martínez-A C; Stone JC; Garcia-Sanz JA; Mérida I
    J Immunol; 2003 Mar; 170(6):2877-83. PubMed ID: 12626538
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Programmed cell death protein 1 activation preferentially inhibits CD28.CAR-T cells.
    Zolov SN; Rietberg SP; Bonifant CL
    Cytotherapy; 2018 Oct; 20(10):1259-1266. PubMed ID: 30309710
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Predominant contribution of DGKζ over DGKα in the control of PKC/PDK-1-regulated functions in T cells.
    Ávila-Flores A; Arranz-Nicolás J; Andrada E; Soutar D; Mérida I
    Immunol Cell Biol; 2017 Jul; 95(6):549-563. PubMed ID: 28163304
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CRISPR/Cas9-mediated PD-1 disruption enhances human mesothelin-targeted CAR T cell effector functions.
    Hu W; Zi Z; Jin Y; Li G; Shao K; Cai Q; Ma X; Wei F
    Cancer Immunol Immunother; 2019 Mar; 68(3):365-377. PubMed ID: 30523370
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aberrant Lck Signal via CD28 Costimulation Augments Antigen-Specific Functionality and Tumor Control by Redirected T Cells with PD-1 Blockade in Humanized Mice.
    Gulati P; Rühl J; Kannan A; Pircher M; Schuberth P; Nytko KJ; Pruschy M; Sulser S; Haefner M; Jensen S; Soltermann A; Jungraithmayr W; Eisenring M; Winder T; Samaras P; Tabor A; Stenger R; Stupp R; Weder W; Renner C; Münz C; Petrausch U
    Clin Cancer Res; 2018 Aug; 24(16):3981-3993. PubMed ID: 29748183
    [No Abstract]   [Full Text] [Related]  

  • 12. CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells.
    Rupp LJ; Schumann K; Roybal KT; Gate RE; Ye CJ; Lim WA; Marson A
    Sci Rep; 2017 Apr; 7(1):737. PubMed ID: 28389661
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Multiplex Genome Editing to Generate Universal CAR T Cells Resistant to PD1 Inhibition.
    Ren J; Liu X; Fang C; Jiang S; June CH; Zhao Y
    Clin Cancer Res; 2017 May; 23(9):2255-2266. PubMed ID: 27815355
    [No Abstract]   [Full Text] [Related]  

  • 14. CD27 costimulation augments the survival and antitumor activity of redirected human T cells in vivo.
    Song DG; Ye Q; Poussin M; Harms GM; Figini M; Powell DJ
    Blood; 2012 Jan; 119(3):696-706. PubMed ID: 22117050
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Disruption of diacylglycerol metabolism impairs the induction of T cell anergy.
    Olenchock BA; Guo R; Carpenter JH; Jordan M; Topham MK; Koretzky GA; Zhong XP
    Nat Immunol; 2006 Nov; 7(11):1174-81. PubMed ID: 17028587
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tumor-Targeted Human T Cells Expressing CD28-Based Chimeric Antigen Receptors Circumvent CTLA-4 Inhibition.
    Condomines M; Arnason J; Benjamin R; Gunset G; Plotkin J; Sadelain M
    PLoS One; 2015; 10(6):e0130518. PubMed ID: 26110267
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma.
    Choi BD; Yu X; Castano AP; Darr H; Henderson DB; Bouffard AA; Larson RC; Scarfò I; Bailey SR; Gerhard GM; Frigault MJ; Leick MB; Schmidts A; Sagert JG; Curry WT; Carter BS; Maus MV
    J Immunother Cancer; 2019 Nov; 7(1):304. PubMed ID: 31727131
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ex vivo Akt inhibition promotes the generation of potent CD19CAR T cells for adoptive immunotherapy.
    Urak R; Walter M; Lim L; Wong CW; Budde LE; Thomas S; Forman SJ; Wang X
    J Immunother Cancer; 2017; 5():26. PubMed ID: 28331616
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy.
    Klepsch V; Pommermayr M; Humer D; Brigo N; Hermann-Kleiter N; Baier G
    Cell Commun Signal; 2020 Jan; 18(1):8. PubMed ID: 31937317
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy.
    Giuffrida L; Sek K; Henderson MA; Lai J; Chen AXY; Meyran D; Todd KL; Petley EV; Mardiana S; Mølck C; Stewart GD; Solomon BJ; Parish IA; Neeson PJ; Harrison SJ; Kats LM; House IG; Darcy PK; Beavis PA
    Nat Commun; 2021 May; 12(1):3236. PubMed ID: 34050151
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.