659 related articles for article (PubMed ID: 29967349)
1. DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia.
Johnson DC; Taabazuing CY; Okondo MC; Chui AJ; Rao SD; Brown FC; Reed C; Peguero E; de Stanchina E; Kentsis A; Bachovchin DA
Nat Med; 2018 Aug; 24(8):1151-1156. PubMed ID: 29967349
[TBL] [Abstract][Full Text] [Related]
2. DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages.
de Vasconcelos NM; Vliegen G; Gonçalves A; De Hert E; Martín-Pérez R; Van Opdenbosch N; Jallapally A; Geiss-Friedlander R; Lambeir AM; Augustyns K; Van Der Veken P; De Meester I; Lamkanfi M
Life Sci Alliance; 2019 Feb; 2(1):. PubMed ID: 30718379
[TBL] [Abstract][Full Text] [Related]
3. DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes.
Johnson DC; Okondo MC; Orth EL; Rao SD; Huang HC; Ball DP; Bachovchin DA
Cell Death Dis; 2020 Aug; 11(8):628. PubMed ID: 32796818
[TBL] [Abstract][Full Text] [Related]
4. Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages.
Taabazuing CY; Okondo MC; Bachovchin DA
Cell Chem Biol; 2017 Apr; 24(4):507-514.e4. PubMed ID: 28392147
[TBL] [Abstract][Full Text] [Related]
5. DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis.
Okondo MC; Johnson DC; Sridharan R; Go EB; Chui AJ; Wang MS; Poplawski SE; Wu W; Liu Y; Lai JH; Sanford DG; Arciprete MO; Golub TR; Bachovchin WW; Bachovchin DA
Nat Chem Biol; 2017 Jan; 13(1):46-53. PubMed ID: 27820798
[TBL] [Abstract][Full Text] [Related]
6. Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment.
Sharif H; Hollingsworth LR; Griswold AR; Hsiao JC; Wang Q; Bachovchin DA; Wu H
Immunity; 2021 Jul; 54(7):1392-1404.e10. PubMed ID: 34019797
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome.
Okondo MC; Rao SD; Taabazuing CY; Chui AJ; Poplawski SE; Johnson DC; Bachovchin DA
Cell Chem Biol; 2018 Mar; 25(3):262-267.e5. PubMed ID: 29396289
[TBL] [Abstract][Full Text] [Related]
8. DPP8/9 inhibitors are universal activators of functional NLRP1 alleles.
Gai K; Okondo MC; Rao SD; Chui AJ; Ball DP; Johnson DC; Bachovchin DA
Cell Death Dis; 2019 Aug; 10(8):587. PubMed ID: 31383852
[TBL] [Abstract][Full Text] [Related]
9. DPP9's Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation.
Griswold AR; Ball DP; Bhattacharjee A; Chui AJ; Rao SD; Taabazuing CY; Bachovchin DA
ACS Chem Biol; 2019 Nov; 14(11):2424-2429. PubMed ID: 31525884
[TBL] [Abstract][Full Text] [Related]
10. Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding.
Zhong FL; Robinson K; Teo DET; Tan KY; Lim C; Harapas CR; Yu CH; Xie WH; Sobota RM; Au VB; Hopkins R; D'Osualdo A; Reed JC; Connolly JE; Masters SL; Reversade B
J Biol Chem; 2018 Dec; 293(49):18864-18878. PubMed ID: 30291141
[TBL] [Abstract][Full Text] [Related]
11. Activation of the CARD8 Inflammasome Requires a Disordered Region.
Chui AJ; Griswold AR; Taabazuing CY; Orth EL; Gai K; Rao SD; Ball DP; Hsiao JC; Bachovchin DA
Cell Rep; 2020 Oct; 33(2):108264. PubMed ID: 33053349
[TBL] [Abstract][Full Text] [Related]
12. Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis.
Matheeussen V; Waumans Y; Martinet W; Van Goethem S; Van der Veken P; Scharpé S; Augustyns K; De Meyer GR; De Meester I
Basic Res Cardiol; 2013 May; 108(3):350. PubMed ID: 23608773
[TBL] [Abstract][Full Text] [Related]
13. CARD8 inflammasome activation triggers pyroptosis in human T cells.
Linder A; Bauernfried S; Cheng Y; Albanese M; Jung C; Keppler OT; Hornung V
EMBO J; 2020 Oct; 39(19):e105071. PubMed ID: 32840892
[TBL] [Abstract][Full Text] [Related]
14. Highly Selective Inhibitors of Dipeptidyl Peptidase 9 (DPP9) Derived from the Clinically Used DPP4-Inhibitor Vildagliptin.
Benramdane S; De Loose J; Filippi N; Espadinha M; Beyens O; Rymenant YV; Dirkx L; Bozdag M; Feijens PB; Augustyns K; Caljon G; De Winter H; De Meester I; Van der Veken P
J Med Chem; 2023 Sep; 66(18):12717-12738. PubMed ID: 37721854
[TBL] [Abstract][Full Text] [Related]
15. DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation.
Hollingsworth LR; Sharif H; Griswold AR; Fontana P; Mintseris J; Dagbay KB; Paulo JA; Gygi SP; Bachovchin DA; Wu H
Nature; 2021 Apr; 592(7856):778-783. PubMed ID: 33731932
[TBL] [Abstract][Full Text] [Related]
16. Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9.
Lankas GR; Leiting B; Roy RS; Eiermann GJ; Beconi MG; Biftu T; Chan CC; Edmondson S; Feeney WP; He H; Ippolito DE; Kim D; Lyons KA; Ok HO; Patel RA; Petrov AN; Pryor KA; Qian X; Reigle L; Woods A; Wu JK; Zaller D; Zhang X; Zhu L; Weber AE; Thornberry NA
Diabetes; 2005 Oct; 54(10):2988-94. PubMed ID: 16186403
[TBL] [Abstract][Full Text] [Related]
17. Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal?
Van Goethem S; Matheeussen V; Joossens J; Lambeir AM; Chen X; De Meester I; Haemers A; Augustyns K; Van der Veken P
J Med Chem; 2011 Aug; 54(16):5737-46. PubMed ID: 21711053
[TBL] [Abstract][Full Text] [Related]
18. The SUMO1-E67 interacting loop peptide is an allosteric inhibitor of the dipeptidyl peptidases 8 and 9.
Pilla E; Kilisch M; Lenz C; Urlaub H; Geiss-Friedlander R
J Biol Chem; 2013 Nov; 288(45):32787-32796. PubMed ID: 24072711
[TBL] [Abstract][Full Text] [Related]
19. N-terminal degradation activates the NLRP1B inflammasome.
Chui AJ; Okondo MC; Rao SD; Gai K; Griswold AR; Johnson DC; Ball DP; Taabazuing CY; Orth EL; Vittimberga BA; Bachovchin DA
Science; 2019 Apr; 364(6435):82-85. PubMed ID: 30872531
[TBL] [Abstract][Full Text] [Related]
20. Regulation of dipeptidyl peptidase 8 and 9 expression in activated lymphocytes and injured liver.
Chowdhury S; Chen Y; Yao TW; Ajami K; Wang XM; Popov Y; Schuppan D; Bertolino P; McCaughan GW; Yu DM; Gorrell MD
World J Gastroenterol; 2013 May; 19(19):2883-93. PubMed ID: 23704821
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
