These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

694 related articles for article (PubMed ID: 2997227)

  • 1. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.
    Hsiang YH; Hertzberg R; Hecht S; Liu LF
    J Biol Chem; 1985 Nov; 260(27):14873-8. PubMed ID: 2997227
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.
    Tewey KM; Chen GL; Nelson EM; Liu LF
    J Biol Chem; 1984 Jul; 259(14):9182-7. PubMed ID: 6086625
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of mammalian DNA topoisomerase I and II mediated DNA cleavage by saintopin, a new antitumor agent from fungus.
    Yamashita Y; Kawada S; Fujii N; Nakano H
    Biochemistry; 1991 Jun; 30(24):5838-45. PubMed ID: 1646001
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin.
    Hsiang YH; Liu LF
    Cancer Res; 1988 Apr; 48(7):1722-6. PubMed ID: 2832051
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Contribution of topoisomerase I to conversion of single-strand into double-strand DNA breaks.
    Kowalska-Loth B; Bubko I; Komorowska B; Szumiel I; Staron K
    Mol Biol Rep; 1998 Jan; 25(1):21-6. PubMed ID: 9540064
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Camptothecin inhibits hsp 70 heat-shock transcription and induces DNA strand breaks in hsp 70 genes in Drosophila.
    Rowe TC; Couto E; Kroll DJ
    NCI Monogr; 1987; (4):49-53. PubMed ID: 2819731
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of CPT on the calf thymus Topoisomerase I-mediated DNA breakage-reunion reaction: optimal conditions for the formation and reversal of the CPT trapped Topoisomerase I cleavable complex.
    Coderoni S; Paparelli M; Gianfranceschi GL
    Mol Biol Rep; 1993 Feb; 17(2):129-34. PubMed ID: 8384692
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The sensitivity to DNA topoisomerase inhibitors in L5178Y lymphoma strains is not related to a primary defect of DNA topoisomerases.
    Lanza A; Tornaletti S; Stefanini M; Evans HH; Ricanati M; Astaldi Ricotti GC; Pedrini AM
    Carcinogenesis; 1993 Sep; 14(9):1759-63. PubMed ID: 8403196
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of CPT on the DNA cleavage/religation reaction mediated by calf thymus Topoisomerase I: evidence of an inhibition of DNA religation. Inhibition of Topoisomerase I-mediated DNA religation by CPT.
    Carboni MC; Coderoni S
    Mol Biol Rep; 1994-1995; 20(3):129-33. PubMed ID: 7565652
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protein-linked DNA strand breaks induced in mammalian cells by camptothecin, an inhibitor of topoisomerase I.
    Covey JM; Jaxel C; Kohn KW; Pommier Y
    Cancer Res; 1989 Sep; 49(18):5016-22. PubMed ID: 2548707
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Effect of camptothecin on the DNA-relaxing and DNA-cleavage activity of calf thymus topoisomerase I].
    Bronshteĭn IB; Gromova II; Bukhman VL; Kafiani KA
    Mol Biol (Mosk); 1989; 23(2):491-501. PubMed ID: 2549395
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin.
    Hsiang YH; Lihou MG; Liu LF
    Cancer Res; 1989 Sep; 49(18):5077-82. PubMed ID: 2548710
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA minor groove-binding ligands: a different class of mammalian DNA topoisomerase I inhibitors.
    Chen AY; Yu C; Gatto B; Liu LF
    Proc Natl Acad Sci U S A; 1993 Sep; 90(17):8131-5. PubMed ID: 7690143
    [TBL] [Abstract][Full Text] [Related]  

  • 14. On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex.
    Hertzberg RP; Caranfa MJ; Hecht SM
    Biochemistry; 1989 May; 28(11):4629-38. PubMed ID: 2548584
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential cytotoxic pathways of topoisomerase I and II anticancer agents after overexpression of the E2F-1/DP-1 transcription factor complex.
    Hofland K; Petersen BO; Falck J; Helin K; Jensen PB; Sehested M
    Clin Cancer Res; 2000 Apr; 6(4):1488-97. PubMed ID: 10778981
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Irreversible trapping of the DNA-topoisomerase I covalent complex. Affinity labeling of the camptothecin binding site.
    Hertzberg RP; Busby RW; Caranfa MJ; Holden KG; Johnson RK; Hecht SM; Kingsbury WD
    J Biol Chem; 1990 Nov; 265(31):19287-95. PubMed ID: 2172250
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interaction between replication forks and topoisomerase I-DNA cleavable complexes: studies in a cell-free SV40 DNA replication system.
    Tsao YP; Russo A; Nyamuswa G; Silber R; Liu LF
    Cancer Res; 1993 Dec; 53(24):5908-14. PubMed ID: 8261402
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.
    Chen GL; Yang L; Rowe TC; Halligan BD; Tewey KM; Liu LF
    J Biol Chem; 1984 Nov; 259(21):13560-6. PubMed ID: 6092381
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fluorometric assays for DNA topoisomerases and topoisomerase-targeted drugs: quantitation of catalytic activity and DNA cleavage.
    Andrea JE; Adachi K; Morgan AR
    Mol Pharmacol; 1991 Oct; 40(4):495-501. PubMed ID: 1656189
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Quinobenoxazines: a class of novel antitumor quinolones and potent mammalian DNA topoisomerase II catalytic inhibitors.
    Permana PA; Snapka RM; Shen LL; Chu DT; Clement JJ; Plattner JJ
    Biochemistry; 1994 Sep; 33(37):11333-9. PubMed ID: 7727384
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 35.