BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 29979714)

  • 1. Construction of an integrated database for hERG blocking small molecules.
    Sato T; Yuki H; Ogura K; Honma T
    PLoS One; 2018; 13(7):e0199348. PubMed ID: 29979714
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In silico prediction of hERG inhibition.
    Jing Y; Easter A; Peters D; Kim N; Enyedy IJ
    Future Med Chem; 2015; 7(5):571-86. PubMed ID: 25921399
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A comprehensive support vector machine binary hERG classification model based on extensive but biased end point hERG data sets.
    Shen MY; Su BH; Esposito EX; Hopfinger AJ; Tseng YJ
    Chem Res Toxicol; 2011 Jun; 24(6):934-49. PubMed ID: 21504223
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In silico prediction of the chemical block of human ether-a-go-go-related gene (hERG) K+ current.
    Inanobe A; Kamiya N; Murakami S; Fukunishi Y; Nakamura H; Kurachi Y
    J Physiol Sci; 2008 Dec; 58(7):459-70. PubMed ID: 19032804
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ADMET evaluation in drug discovery. 12. Development of binary classification models for prediction of hERG potassium channel blockage.
    Wang S; Li Y; Wang J; Chen L; Zhang L; Yu H; Hou T
    Mol Pharm; 2012 Apr; 9(4):996-1010. PubMed ID: 22380484
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Combined receptor and ligand-based approach to the universal pharmacophore model development for studies of drug blockade to the hERG1 pore domain.
    Durdagi S; Duff HJ; Noskov SY
    J Chem Inf Model; 2011 Feb; 51(2):463-74. PubMed ID: 21241063
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prospective validation of a comprehensive in silico hERG model and its applications to commercial compound and drug databases.
    Doddareddy MR; Klaasse EC; Shagufta ; Ijzerman AP; Bender A
    ChemMedChem; 2010 May; 5(5):716-29. PubMed ID: 20349498
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Determination of hERG channel blockers using a decision tree.
    Gepp MM; Hutter MC
    Bioorg Med Chem; 2006 Aug; 14(15):5325-32. PubMed ID: 16616507
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insights for human ether-a-go-go-related gene potassium channel inhibition using recursive partitioning and Kohonen and Sammon mapping techniques.
    Ekins S; Balakin KV; Savchuk N; Ivanenkov Y
    J Med Chem; 2006 Aug; 49(17):5059-71. PubMed ID: 16913696
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modeling of the hERG K+ Channel Blockage Using Online Chemical Database and Modeling Environment (OCHEM).
    Li X; Zhang Y; Li H; Zhao Y
    Mol Inform; 2017 Dec; 36(12):. PubMed ID: 28857516
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A critical assessment of combined ligand- and structure-based approaches to HERG channel blocker modeling.
    Du-Cuny L; Chen L; Zhang S
    J Chem Inf Model; 2011 Nov; 51(11):2948-60. PubMed ID: 21902220
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Indexing molecules for their hERG liability.
    Rayan A; Falah M; Raiyn J; Da'adoosh B; Kadan S; Zaid H; Goldblum A
    Eur J Med Chem; 2013 Jul; 65():304-14. PubMed ID: 23727540
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recent developments in computational prediction of HERG blockage.
    Wang S; Li Y; Xu L; Li D; Hou T
    Curr Top Med Chem; 2013; 13(11):1317-26. PubMed ID: 23675938
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In silico predictions of hERG channel blockers in drug discovery: from ligand-based and target-based approaches to systems chemical biology.
    Taboureau O; Jørgensen FS
    Comb Chem High Throughput Screen; 2011 Jun; 14(5):375-87. PubMed ID: 21470179
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Similarity-based SIBAR descriptors for classification of chemically diverse hERG blockers.
    Thai KM; Ecker GF
    Mol Divers; 2009 Aug; 13(3):321-36. PubMed ID: 19219559
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human ether-a-go-go-related gene channel blockers and its structural analysis for drug design.
    Narayana Moorthy NS; Ramos MJ; Fernandes PA
    Curr Drug Targets; 2013 Jan; 14(1):102-13. PubMed ID: 23061466
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Study on the hERG Blocker Prediction Using Chemical Fingerprint Analysis.
    Choi KE; Balupuri A; Kang NS
    Molecules; 2020 Jun; 25(11):. PubMed ID: 32512802
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tuning HERG out: antitarget QSAR models for drug development.
    Braga RC; Alves VM; Silva MF; Muratov E; Fourches D; Tropsha A; Andrade CH
    Curr Top Med Chem; 2014; 14(11):1399-415. PubMed ID: 24805060
    [TBL] [Abstract][Full Text] [Related]  

  • 19. hERGCentral: a large database to store, retrieve, and analyze compound-human Ether-à-go-go related gene channel interactions to facilitate cardiotoxicity assessment in drug development.
    Du F; Yu H; Zou B; Babcock J; Long S; Li M
    Assay Drug Dev Technol; 2011 Dec; 9(6):580-8. PubMed ID: 22149888
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Common pharmacophores for uncharged human ether-a-go-go-related gene (hERG) blockers.
    Aronov AM
    J Med Chem; 2006 Nov; 49(23):6917-21. PubMed ID: 17154521
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.