BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

244 related articles for article (PubMed ID: 29987014)

  • 1. Hsp70-Bag3 complex is a hub for proteotoxicity-induced signaling that controls protein aggregation.
    Meriin AB; Narayanan A; Meng L; Alexandrov I; Varelas X; Cissé II; Sherman MY
    Proc Natl Acad Sci U S A; 2018 Jul; 115(30):E7043-E7052. PubMed ID: 29987014
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP-HSP70-BAG3 complex and the aggregation of ubiquitinated proteins.
    Zhang C; Tang Q; Xia H; Xu H; Bi F
    FASEB J; 2022 Jan; 36(1):e22121. PubMed ID: 34951719
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Hsp70-Bag3 complex modulates the phosphorylation and nuclear translocation of Hippo pathway protein Yap.
    Baldan S; Meriin AB; Yaglom J; Alexandrov I; Varelas X; Xiao ZJ; Sherman MY
    J Cell Sci; 2021 Dec; 134(23):. PubMed ID: 34761265
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks.
    Meister-Broekema M; Freilich R; Jagadeesan C; Rauch JN; Bengoechea R; Motley WW; Kuiper EFE; Minoia M; Furtado GV; van Waarde MAWH; Bird SJ; Rebelo A; Zuchner S; Pytel P; Scherer SS; Morelli FF; Carra S; Weihl CC; Bergink S; Gestwicki JE; Kampinga HH
    Nat Commun; 2018 Dec; 9(1):5342. PubMed ID: 30559338
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of Bag3 in cell signaling.
    Sherman MY; Gabai V
    J Cell Biochem; 2022 Jan; 123(1):43-53. PubMed ID: 34297413
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism.
    Ganassi M; Mateju D; Bigi I; Mediani L; Poser I; Lee HO; Seguin SJ; Morelli FF; Vinet J; Leo G; Pansarasa O; Cereda C; Poletti A; Alberti S; Carra S
    Mol Cell; 2016 Sep; 63(5):796-810. PubMed ID: 27570075
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BAG3 Is a Modular, Scaffolding Protein that physically Links Heat Shock Protein 70 (Hsp70) to the Small Heat Shock Proteins.
    Rauch JN; Tse E; Freilich R; Mok SA; Makley LN; Southworth DR; Gestwicki JE
    J Mol Biol; 2017 Jan; 429(1):128-141. PubMed ID: 27884606
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HSPB8 and BAG3 cooperate to promote spatial sequestration of ubiquitinated proteins and coordinate the cellular adaptive response to proteasome insufficiency.
    Guilbert SM; Lambert H; Rodrigue MA; Fuchs M; Landry J; Lavoie JN
    FASEB J; 2018 Jul; 32(7):3518-3535. PubMed ID: 29405094
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacological inhibition of BAG3-HSP70 with the proposed cancer therapeutic JG-98 is toxic for cardiomyocytes.
    Martin TG; Delligatti CE; Muntu NA; Stachowski-Doll MJ; Kirk JA
    J Cell Biochem; 2022 Jan; 123(1):128-141. PubMed ID: 34487557
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Breaking BAG: The Co-Chaperone BAG3 in Health and Disease.
    Behl C
    Trends Pharmacol Sci; 2016 Aug; 37(8):672-688. PubMed ID: 27162137
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lamin B is a target for selective nuclear PQC by BAG3: implication for nuclear envelopathies.
    Gupta MK; Gordon J; Glauser GM; Myers VD; Feldman AM; Cheung JY; Khalili K
    Cell Death Dis; 2019 Jan; 10(1):23. PubMed ID: 30631036
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inducible HSP70 is critical in preventing the aggregation and enhancing the processing of PMP22.
    Chittoor-Vinod VG; Lee S; Judge SM; Notterpek L
    ASN Neuro; 2015; 7(1):. PubMed ID: 25694550
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BAG3 expression in glioblastoma cells promotes accumulation of ubiquitinated clients in an Hsp70-dependent manner.
    Gentilella A; Khalili K
    J Biol Chem; 2011 Mar; 286(11):9205-15. PubMed ID: 21233200
    [TBL] [Abstract][Full Text] [Related]  

  • 14. BAG3 induction is required to mitigate proteotoxicity via selective autophagy following inhibition of constitutive protein degradation pathways.
    Rapino F; Jung M; Fulda S
    Oncogene; 2014 Mar; 33(13):1713-24. PubMed ID: 23644654
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BAG3 Proteomic Signature under Proteostasis Stress.
    Hiebel C; Stürner E; Hoffmeister M; Tascher G; Schwarz M; Nagel H; Behrends C; Münch C; Behl C
    Cells; 2020 Nov; 9(11):. PubMed ID: 33158300
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Hippo network kinase STK38 contributes to protein homeostasis by inhibiting BAG3-mediated autophagy.
    Klimek C; Jahnke R; Wördehoff J; Kathage B; Stadel D; Behrends C; Hergovich A; Höhfeld J
    Biochim Biophys Acta Mol Cell Res; 2019 Oct; 1866(10):1556-1566. PubMed ID: 31326538
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hsp70 in cancer: back to the future.
    Sherman MY; Gabai VL
    Oncogene; 2015 Aug; 34(32):4153-61. PubMed ID: 25347739
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of HSP70 and its co-chaperones in protein misfolding, aggregation and disease.
    Duncan EJ; Cheetham ME; Chapple JP; van der Spuy J
    Subcell Biochem; 2015; 78():243-73. PubMed ID: 25487025
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BAG3 and BAG6 differentially affect the dynamics of stress granules by targeting distinct subsets of defective polypeptides released from ribosomes.
    Mediani L; Galli V; Carrà AD; Bigi I; Vinet J; Ganassi M; Antoniani F; Tiago T; Cimino M; Mateju D; Cereda C; Pansarasa O; Alberti S; Mandrioli J; Carra S
    Cell Stress Chaperones; 2020 Nov; 25(6):1045-1058. PubMed ID: 32696179
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1.
    Kathage B; Gehlert S; Ulbricht A; Lüdecke L; Tapia VE; Orfanos Z; Wenzel D; Bloch W; Volkmer R; Fleischmann BK; Fürst DO; Höhfeld J
    Biochim Biophys Acta Mol Cell Res; 2017 Jan; 1864(1):62-75. PubMed ID: 27756573
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.