BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 29987190)

  • 1. The N Termini of TAR DNA-Binding Protein 43 (TDP43) C-Terminal Fragments Influence Degradation, Aggregation Propensity, and Morphology.
    Kasu YAT; Alemu S; Lamari A; Loew N; Brower CS
    Mol Cell Biol; 2018 Oct; 38(19):. PubMed ID: 29987190
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interaction of RNA with a C-terminal fragment of the amyotrophic lateral sclerosis-associated TDP43 reduces cytotoxicity.
    Kitamura A; Nakayama Y; Shibasaki A; Taki A; Yuno S; Takeda K; Yahara M; Tanabe N; Kinjo M
    Sci Rep; 2016 Jan; 6():19230. PubMed ID: 26757674
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tdp-25 Routing to Autophagy and Proteasome Ameliorates its Aggregation in Amyotrophic Lateral Sclerosis Target Cells.
    Cicardi ME; Cristofani R; Rusmini P; Meroni M; Ferrari V; Vezzoli G; Tedesco B; Piccolella M; Messi E; Galbiati M; Boncoraglio A; Carra S; Crippa V; Poletti A
    Sci Rep; 2018 Aug; 8(1):12390. PubMed ID: 30120266
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neurodegeneration-associated protein fragments as short-lived substrates of the N-end rule pathway.
    Brower CS; Piatkov KI; Varshavsky A
    Mol Cell; 2013 Apr; 50(2):161-71. PubMed ID: 23499006
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy.
    Cascella R; Fani G; Capitini C; Rusmini P; Poletti A; Cecchi C; Chiti F
    FASEB J; 2017 Dec; 31(12):5609-5624. PubMed ID: 28842427
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Poly(ADP-ribose) Engages the TDP-43 Nuclear-Localization Sequence to Regulate Granulo-Filamentous Aggregation.
    McGurk L; Gomes E; Guo L; Shorter J; Bonini NM
    Biochemistry; 2018 Dec; 57(51):6923-6926. PubMed ID: 30540446
    [TBL] [Abstract][Full Text] [Related]  

  • 7. N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis.
    Yoo YD; Mun SR; Ji CH; Sung KW; Kang KY; Heo AJ; Lee SH; An JY; Hwang J; Xie XQ; Ciechanover A; Kim BY; Kwon YT
    Proc Natl Acad Sci U S A; 2018 Mar; 115(12):E2716-E2724. PubMed ID: 29507222
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Induction of amyloid fibrils by the C-terminal fragments of TDP-43 in amyotrophic lateral sclerosis.
    Chen AK; Lin RY; Hsieh EZ; Tu PH; Chen RP; Liao TY; Chen W; Wang CH; Huang JJ
    J Am Chem Soc; 2010 Feb; 132(4):1186-7. PubMed ID: 20055380
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Computational Approach to Investigate TDP-43 RNA-Recognition Motif 2 C-Terminal Fragments Aggregation in Amyotrophic Lateral Sclerosis.
    Grassmann G; Miotto M; Di Rienzo L; Salaris F; Silvestri B; Zacco E; Rosa A; Tartaglia GG; Ruocco G; Milanetti E
    Biomolecules; 2021 Dec; 11(12):. PubMed ID: 34944548
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Triad of TDP43 control in neurodegeneration: autoregulation, localization and aggregation.
    Tziortzouda P; Van Den Bosch L; Hirth F
    Nat Rev Neurosci; 2021 Apr; 22(4):197-208. PubMed ID: 33654312
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Age-dependent neurodegeneration and organelle transport deficiencies in mutant TDP43 patient-derived neurons are independent of TDP43 aggregation.
    Kreiter N; Pal A; Lojewski X; Corcia P; Naujock M; Reinhardt P; Sterneckert J; Petri S; Wegner F; Storch A; Hermann A
    Neurobiol Dis; 2018 Jul; 115():167-181. PubMed ID: 29630989
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular properties of TAR DNA binding protein-43 fragments are dependent upon its cleavage site.
    Furukawa Y; Kaneko K; Nukina N
    Biochim Biophys Acta; 2011 Dec; 1812(12):1577-83. PubMed ID: 21946215
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Haploinsufficiency of the TDP43 ubiquitin E3 ligase RNF220 leads to ALS-like motor neuron defects in the mouse.
    Ma P; Li Y; Wang H; Mao B
    J Mol Cell Biol; 2021 Aug; 13(5):374-382. PubMed ID: 33386850
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The proteinopathy of D169G and K263E mutants at the RNA Recognition Motif (RRM) domain of tar DNA-binding protein (tdp43) causing neurological disorders: A computational study.
    Bhandare VV; Ramaswamy A
    J Biomol Struct Dyn; 2018 Mar; 36(4):1075-1093. PubMed ID: 28330421
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Different Chronic Stress Paradigms Converge on Endogenous TDP43 Cleavage and Aggregation.
    Candelise N; Caissutti D; Zenuni H; Nesci V; Scaricamazza S; Salvatori I; Spinello Z; Mattei V; Garofalo T; Ferri A; Valle C; Misasi R
    Mol Neurobiol; 2023 Nov; 60(11):6346-6361. PubMed ID: 37450246
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ALS-causing cleavages of TDP-43 abolish its RRM2 structure and unlock CTD for enhanced aggregation and toxicity.
    Wei Y; Lim L; Wang L; Song J
    Biochem Biophys Res Commun; 2017 Apr; 485(4):826-831. PubMed ID: 28257838
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Elimination of TDP-43 inclusions linked to amyotrophic lateral sclerosis by a misfolding-specific intrabody with dual proteolytic signals.
    Tamaki Y; Shodai A; Morimura T; Hikiami R; Minamiyama S; Ayaki T; Tooyama I; Furukawa Y; Takahashi R; Urushitani M
    Sci Rep; 2018 Apr; 8(1):6030. PubMed ID: 29662239
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species.
    Scotter EL; Vance C; Nishimura AL; Lee YB; Chen HJ; Urwin H; Sardone V; Mitchell JC; Rogelj B; Rubinsztein DC; Shaw CE
    J Cell Sci; 2014 Mar; 127(Pt 6):1263-78. PubMed ID: 24424030
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models.
    Barmada SJ; Serio A; Arjun A; Bilican B; Daub A; Ando DM; Tsvetkov A; Pleiss M; Li X; Peisach D; Shaw C; Chandran S; Finkbeiner S
    Nat Chem Biol; 2014 Aug; 10(8):677-85. PubMed ID: 24974230
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Delineation of the core aggregation sequences of TDP-43 C-terminal fragment.
    Saini A; Chauhan VS
    Chembiochem; 2011 Nov; 12(16):2495-501. PubMed ID: 21905193
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.