BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 29990424)

  • 1. Discovery of the Polyamine Conjugate with Benzo[ cd]indol-2(1 H)-one as a Lysosome-Targeted Antimetastatic Agent.
    Li J; Tian R; Ge C; Chen Y; Liu X; Wang Y; Yang Y; Luo W; Dai F; Wang S; Chen S; Xie S; Wang C
    J Med Chem; 2018 Aug; 61(15):6814-6829. PubMed ID: 29990424
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A naphthalimide-polyamine conjugate preferentially accumulates in hepatic carcinoma metastases as a lysosome-targeted antimetastatic agent.
    Ma J; Li L; Yue K; Zhang Z; Su S; Chen Y; Yu L; Zhang P; Ma R; Li Y; Ma Y; Jia H; Wang C; Wang J; Xie S
    Eur J Med Chem; 2021 Oct; 221():113469. PubMed ID: 33965862
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, Synthesis, and Biological Evaluation of Benzo[cd]indol-2(1H)-ones Derivatives as a Lysosome-Targeted Anti-metastatic Agent.
    Li J; Chen S; Zhao Y; Gong H; Wang T; Ge X; Wang Y; Zhu C; Chen L; Dai F; Xie S; Wang C; Luo W
    Front Oncol; 2021; 11():733589. PubMed ID: 34540699
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The lead optimization of the polyamine conjugate of flavonoid with a naphthalene motif: Synthesis and biological evaluation.
    Li Q; Zhu ZX; Zhang X; Luo W; Chang LP; Chen S; Wang YX; Xie SQ; Chang CC; Wang CJ
    Eur J Med Chem; 2018 Feb; 146():564-576. PubMed ID: 29407981
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of naphthalimide-polyamine conjugates modified by alkylation as anticancer agents through p53 pathway.
    Dai F; He H; Xu X; Chen S; Wang C; Feng C; Tian Z; Dong H; Xie S
    Bioorg Chem; 2018 Apr; 77():16-24. PubMed ID: 29316508
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, Biological Activity and Preliminary in Silico ADMET Screening of Polyamine Conjugates with Bicyclic Systems.
    Szumilak M; Galdyszynska M; Dominska K; Bak-Sypien II; Merecz-Sadowska A; Stanczak A; Karwowski BT; Piastowska-Ciesielska AW
    Molecules; 2017 May; 22(5):. PubMed ID: 28498338
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and multi-step synthesis of chalcone-polyamine conjugates as potent antiproliferative agents.
    Rioux B; Pouget C; Fidanzi-Dugas C; Gamond A; Laurent A; Semaan J; Pinon A; Champavier Y; Léger DY; Liagre B; Duroux JL; Fagnère C; Sol V
    Bioorg Med Chem Lett; 2017 Sep; 27(18):4354-4357. PubMed ID: 28838697
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of novel alkylated polyamine analogues as potential anticancer agents.
    Li M; Wang Y; Ge C; Chang L; Wang C; Tian Z; Wang S; Dai F; Zhao L; Xie S
    Eur J Med Chem; 2018 Jan; 143():1732-1743. PubMed ID: 29133040
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthetic polyamines activating autophagy: effects on cancer cell death.
    Minarini A; Zini M; Milelli A; Tumiatti V; Marchetti C; Nicolini B; Falconi M; Farruggia G; Cappadone C; Stefanelli C
    Eur J Med Chem; 2013 Sep; 67():359-66. PubMed ID: 23887056
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, Synthesis, and Biological Evaluation of Mitochondria-Targeted Flavone-Naphthalimide-Polyamine Conjugates with Antimetastatic Activity.
    Dai F; Li Q; Wang Y; Ge C; Feng C; Xie S; He H; Xu X; Wang C
    J Med Chem; 2017 Mar; 60(5):2071-2083. PubMed ID: 28177238
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Parallel synthesis and cytotoxicity evaluation of a polyamine-quinone conjugates library.
    Bolognesi ML; Calonghi N; Mangano C; Masotti L; Melchiorre C
    J Med Chem; 2008 Sep; 51(17):5463-7. PubMed ID: 18698755
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ant 4,4, a polyamine-anthracene conjugate, induces cell death and recovery in human promyelogenous leukemia cells (HL-60).
    Traquete R; Ghani RA; Phanstiel O; Wallace HM
    Amino Acids; 2013 Apr; 44(4):1193-203. PubMed ID: 23292094
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and Biological Evaluation of Novel Aromatic Imide-Polyamine Conjugates.
    Li M; Wang Y; Zhang J; Xie S; Wang C; Wu Y
    Molecules; 2016 Nov; 21(12):. PubMed ID: 27916902
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Celecoxib exerts antitumor effects in HL-60 acute leukemia cells and inhibits autophagy by affecting lysosome function.
    Lu Y; Liu XF; Liu TR; Fan RF; Xu YC; Zhang XZ; Liu LL
    Biomed Pharmacother; 2016 Dec; 84():1551-1557. PubMed ID: 27884749
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phthalocyanine-polyamine conjugates as pH-controlled photosensitizers for photodynamic therapy.
    Jiang XJ; Lo PC; Tsang YM; Yeung SL; Fong WP; Ng DK
    Chemistry; 2010 Apr; 16(16):4777-83. PubMed ID: 20309976
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nonhematotoxic naphthalene diimide modified by polyamine: synthesis and biological evaluation.
    Wang Y; Zhang X; Zhao J; Xie S; Wang C
    J Med Chem; 2012 Apr; 55(7):3502-12. PubMed ID: 22428910
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Initial autophagic protection switches to disruption of autophagic flux by lysosomal instability during cadmium stress accrual in renal NRK-52E cells.
    Lee WK; Probst S; Santoyo-Sánchez MP; Al-Hamdani W; Diebels I; von Sivers JK; Kerek E; Prenner EJ; Thévenod F
    Arch Toxicol; 2017 Oct; 91(10):3225-3245. PubMed ID: 28321485
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells.
    Huang Y; Hager ER; Phillips DL; Dunn VR; Hacker A; Frydman B; Kink JA; Valasinas AL; Reddy VK; Marton LJ; Casero RA; Davidson NE
    Clin Cancer Res; 2003 Jul; 9(7):2769-77. PubMed ID: 12855657
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino[1,2-a]indol-1(2H)-ones as potential anticancer agents effecting the reactive oxygen species production.
    Youssif BGM; Abdelrahman MH; Abdelazeem AH; Abdelgawad MA; Ibrahim HM; Salem OIA; Mohamed MFA; Treambleau L; Bukhari SNA
    Eur J Med Chem; 2018 Feb; 146():260-273. PubMed ID: 29407956
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Apoptotic signaling in polyamine analogue-treated SK-MEL-28 human melanoma cells.
    Chen Y; Kramer DL; Diegelman P; Vujcic S; Porter CW
    Cancer Res; 2001 Sep; 61(17):6437-44. PubMed ID: 11522638
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.