These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. In search of a catalytic bioscavenger for the prophylaxis of nerve agent toxicity. diTargiani RC; Chandrasekaran L; Belinskaya T; Saxena A Chem Biol Interact; 2010 Sep; 187(1-3):349-54. PubMed ID: 20176006 [TBL] [Abstract][Full Text] [Related]
6. In vitro evaluation of the catalytic activity of paraoxonases and phosphotriesterases predicts the enzyme circulatory levels required for in vivo protection against organophosphate intoxications. Ashani Y; Leader H; Aggarwal N; Silman I; Worek F; Sussman JL; Goldsmith M Chem Biol Interact; 2016 Nov; 259(Pt B):252-256. PubMed ID: 27163850 [TBL] [Abstract][Full Text] [Related]
7. Catalytic bioscavengers against toxic esters, an alternative approach for prophylaxis and treatments of poisonings. Masson P; Rochu D Acta Naturae; 2009 Apr; 1(1):68-79. PubMed ID: 22649587 [TBL] [Abstract][Full Text] [Related]
8. Organophosphate hydrolases as catalytic bioscavengers of organophosphorus nerve agents. Trovaslet-Leroy M; Musilova L; Renault F; Brazzolotto X; Misik J; Novotny L; Froment MT; Gillon E; Loiodice M; Verdier L; Masson P; Rochu D; Jun D; Nachon F Toxicol Lett; 2011 Sep; 206(1):14-23. PubMed ID: 21683774 [TBL] [Abstract][Full Text] [Related]
9. Catalytic efficiencies of directly evolved phosphotriesterase variants with structurally different organophosphorus compounds in vitro. Goldsmith M; Eckstein S; Ashani Y; Greisen P; Leader H; Sussman JL; Aggarwal N; Ovchinnikov S; Tawfik DS; Baker D; Thiermann H; Worek F Arch Toxicol; 2016 Nov; 90(11):2711-2724. PubMed ID: 26612364 [TBL] [Abstract][Full Text] [Related]
10. [Engineering of catalytic bioscavengers of organophosphorus compounds]. Masson P; Nachon F; Rochu D Bull Acad Natl Med; 2007 Jan; 191(1):95-111; discussion 112. PubMed ID: 17645110 [TBL] [Abstract][Full Text] [Related]
11. Bioscavengers for the protection of humans against organophosphate toxicity. Doctor BP; Saxena A Chem Biol Interact; 2005 Dec; 157-158():167-71. PubMed ID: 16293236 [TBL] [Abstract][Full Text] [Related]
12. Catalytic bioscavengers in nerve agent poisoning: A promising approach? Worek F; Thiermann H; Wille T Toxicol Lett; 2016 Feb; 244():143-148. PubMed ID: 26200600 [TBL] [Abstract][Full Text] [Related]
13. Enzymes and bioscavengers for prophylaxis and treatment of organophosphate poisoning. Bird SB; Dawson A; Ollis D Front Biosci (Schol Ed); 2010 Jan; 2(1):209-20. PubMed ID: 20036941 [TBL] [Abstract][Full Text] [Related]
14. Single treatment of VX poisoned guinea pigs with the phosphotriesterase mutant C23AL: Intraosseous versus intravenous injection. Wille T; Neumaier K; Koller M; Ehinger C; Aggarwal N; Ashani Y; Goldsmith M; Sussman JL; Tawfik DS; Thiermann H; Worek F Toxicol Lett; 2016 Sep; 258():198-206. PubMed ID: 27397758 [TBL] [Abstract][Full Text] [Related]
15. A catalytic bioscavenger with improved stability and reduced susceptibility to oxidation for treatment of acute poisoning with neurotoxic organophosphorus compounds. Job L; Köhler A; Escher B; Worek F; Skerra A Toxicol Lett; 2020 Mar; 321():138-145. PubMed ID: 31891759 [TBL] [Abstract][Full Text] [Related]
16. Is Human Paraoxonase 1 the Saviour Against the Persistent Threat of Organophosphorus Nerve Agents? Iyengar ARS; Pande AH Protein Pept Lett; 2019; 26(7):471-478. PubMed ID: 30942142 [TBL] [Abstract][Full Text] [Related]
17. Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers. Goldsmith M; Aggarwal N; Ashani Y; Jubran H; Greisen PJ; Ovchinnikov S; Leader H; Baker D; Sussman JL; Goldenzweig A; Fleishman SJ; Tawfik DS Protein Eng Des Sel; 2017 Apr; 30(4):333-345. PubMed ID: 28159998 [TBL] [Abstract][Full Text] [Related]
18. Organophosphate-Hydrolyzing Enzymes as First-Line of Defence Against Nerve Agent-Poisoning: Perspectives and the Road Ahead. Iyengar AR; Pande AH Protein J; 2016 Dec; 35(6):424-439. PubMed ID: 27830420 [TBL] [Abstract][Full Text] [Related]
19. Post-exposure treatment of VX poisoned guinea pigs with the engineered phosphotriesterase mutant C23: a proof-of-concept study. Worek F; Seeger T; Reiter G; Goldsmith M; Ashani Y; Leader H; Sussman JL; Aggarwal N; Thiermann H; Tawfik DS Toxicol Lett; 2014 Nov; 231(1):45-54. PubMed ID: 25195526 [TBL] [Abstract][Full Text] [Related]
20. The potential role of bioscavenger in the medical management of nerve-agent poisoned casualties. Rice H; Mann TM; Armstrong SJ; Price ME; Green AC; Tattersall JEH Chem Biol Interact; 2016 Nov; 259(Pt B):175-181. PubMed ID: 27144491 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]