BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

308 related articles for article (PubMed ID: 29991802)

  • 21. Functional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/Ref-1.
    Kelley MR; Luo M; Reed A; Su D; Delaplane S; Borch RF; Nyland RL; Gross ML; Georgiadis MM
    Antioxid Redox Signal; 2011 Apr; 14(8):1387-401. PubMed ID: 20874257
    [TBL] [Abstract][Full Text] [Related]  

  • 22. APE1 Upregulates MMP-14 via Redox-Sensitive ARF6-Mediated Recycling to Promote Cell Invasion of Esophageal Adenocarcinoma.
    Lu H; Bhat AA; Peng D; Chen Z; Zhu S; Hong J; Maacha S; Yan J; Robbins DJ; Washington MK; Belkhiri A; El-Rifai W
    Cancer Res; 2019 Sep; 79(17):4426-4438. PubMed ID: 31308045
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Cancer-related inflammation and Barrett's carcinogenesis: interleukin-6 and STAT3 mediate apoptotic resistance in transformed Barrett's cells.
    Zhang HY; Zhang Q; Zhang X; Yu C; Huo X; Cheng E; Wang DH; Spechler SJ; Souza RF
    Am J Physiol Gastrointest Liver Physiol; 2011 Mar; 300(3):G454-60. PubMed ID: 21148399
    [TBL] [Abstract][Full Text] [Related]  

  • 24. APE1 stimulates EGFR-TKI resistance by activating Akt signaling through a redox-dependent mechanism in lung adenocarcinoma.
    Lu GS; Li M; Xu CX; Wang D
    Cell Death Dis; 2018 Oct; 9(11):1111. PubMed ID: 30382076
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Activation of NOTCH signaling via DLL1 is mediated by APE1-redox-dependent NF-κB activation in oesophageal adenocarcinoma.
    Chen L; Lu H; Peng D; Cao LL; Ballout F; Srirmajayam K; Chen Z; Bhat A; Wang TC; Capobianco A; Que J; McDonald OG; Zaika A; Zhang S; El-Rifai W
    Gut; 2023 Mar; 72(3):421-432. PubMed ID: 35750470
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Upregulation of the oncogene c-myc in Barrett's adenocarcinoma: induction of c-myc by acidified bile acid in vitro.
    Tselepis C; Morris CD; Wakelin D; Hardy R; Perry I; Luong QT; Harper E; Harrison R; Attwood SE; Jankowski JA
    Gut; 2003 Feb; 52(2):174-80. PubMed ID: 12524396
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Regulation of signal transducer and activator of transcription 3 enhanceosome formation by apurinic/apyrimidinic endonuclease 1 in hepatic acute phase response.
    Ray S; Lee C; Hou T; Bhakat KK; Brasier AR
    Mol Endocrinol; 2010 Feb; 24(2):391-401. PubMed ID: 20032196
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Ape1 regulates WNT/β-catenin signaling through its redox functional domain in pancreatic cancer cells.
    Jiang S; Zhu L; Tang H; Zhang M; Chen Z; Fei J; Han B; Zou GM
    Int J Oncol; 2015 Aug; 47(2):610-20. PubMed ID: 26081414
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Acidic Bile Salts Induce Epithelial to Mesenchymal Transition via VEGF Signaling in Non-Neoplastic Barrett's Cells.
    Zhang Q; Agoston AT; Pham TH; Zhang W; Zhang X; Huo X; Peng S; Bajpai M; Das K; Odze RD; Spechler SJ; Souza RF
    Gastroenterology; 2019 Jan; 156(1):130-144.e10. PubMed ID: 30268789
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocarcinoma.
    Lu H; Cao LL; Ballout F; Belkhiri A; Peng D; Chen L; Chen Z; Soutto M; Wang TC; Que J; Giordano S; Washington MK; Chen S; McDonald OG; Zaika A; El-Rifai W
    Gut; 2023 Dec; 73(1):47-62. PubMed ID: 37734913
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models.
    Logsdon DP; Grimard M; Luo M; Shahda S; Jiang Y; Tong Y; Yu Z; Zyromski N; Schipani E; Carta F; Supuran CT; Korc M; Ivan M; Kelley MR; Fishel ML
    Mol Cancer Ther; 2016 Nov; 15(11):2722-2732. PubMed ID: 27535970
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Toll-like Receptor 2 Signalling and the Lysosomal Machinery in Barrett's Esophagus.
    Verbeek RE; Siersema PD; Vleggaar FP; Ten Kate FJ; Posthuma G; Souza RF; de Haan J; van Baal JW
    J Gastrointestin Liver Dis; 2016 Sep; 25(3):273-82. PubMed ID: 27689189
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Fatty acid synthase expression in Barrett's esophagus: implications for carcinogenesis.
    Ishimura N; Amano Y; Sanchez-Siles AA; Fukuhara H; Takahashi Y; Uno G; Tamagawa Y; Mishima Y; Yuki T; Ishihara S; Kinoshita Y
    J Clin Gastroenterol; 2011 Sep; 45(8):665-72. PubMed ID: 21325951
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival.
    Logsdon DP; Shah F; Carta F; Supuran CT; Kamocka M; Jacobsen MH; Sandusky GE; Kelley MR; Fishel ML
    Sci Rep; 2018 Sep; 8(1):13759. PubMed ID: 30214007
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Loss of glutathione peroxidase 7 promotes TNF-α-induced NF-κB activation in Barrett's carcinogenesis.
    Peng DF; Hu TL; Soutto M; Belkhiri A; El-Rifai W
    Carcinogenesis; 2014 Jul; 35(7):1620-8. PubMed ID: 24692067
    [TBL] [Abstract][Full Text] [Related]  

  • 36. NMR studies reveal an unexpected binding site for a redox inhibitor of AP endonuclease 1.
    Manvilla BA; Wauchope O; Seley-Radtke KL; Drohat AC
    Biochemistry; 2011 Dec; 50(48):10540-9. PubMed ID: 22032234
    [TBL] [Abstract][Full Text] [Related]  

  • 37. APE1/Ref-1 enhances DNA binding activity of mutant p53 in a redox-dependent manner.
    Cun Y; Dai N; Li M; Xiong C; Zhang Q; Sui J; Qian C; Wang D
    Oncol Rep; 2014 Feb; 31(2):901-9. PubMed ID: 24297337
    [TBL] [Abstract][Full Text] [Related]  

  • 38. NRF2 antioxidant response protects against acidic bile salts-induced oxidative stress and DNA damage in esophageal cells.
    Peng D; Lu H; Zhu S; Zhou Z; Hu T; Chen Z; Zaika A; El-Rifai W
    Cancer Lett; 2019 Aug; 458():46-55. PubMed ID: 31132430
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Characterization of squamous esophageal cells resistant to bile acids at acidic pH: implication for Barrett's esophagus pathogenesis.
    Goldman A; Chen HD; Roesly HB; Hill KA; Tome ME; Dvorak B; Bernstein H; Dvorak K
    Am J Physiol Gastrointest Liver Physiol; 2011 Feb; 300(2):G292-302. PubMed ID: 21127259
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Design and synthesis of novel quinone inhibitors targeted to the redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor-1 (Ape1/ref-1).
    Nyland RL; Luo M; Kelley MR; Borch RF
    J Med Chem; 2010 Feb; 53(3):1200-10. PubMed ID: 20067291
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.