BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 30003105)

  • 1. Human MLL-AF9 Overexpression Induces Aberrant Hematopoietic Expansion in Zebrafish.
    Tan J; Zhao L; Wang G; Li T; Li D; Xu Q; Chen X; Shang Z; Wang J; Zhou J
    Biomed Res Int; 2018; 2018():6705842. PubMed ID: 30003105
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Myeloid Targeted Human MLL-ENL and MLL-AF9 Induces cdk9 and bcl2 Expression in Zebrafish Embryos.
    Belt AJ; Grant S; Tombes RM; Rothschild SC
    PLoS Genet; 2024 Jun; 20(6):e1011308. PubMed ID: 38829886
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.
    Thiel AT; Blessington P; Zou T; Feather D; Wu X; Yan J; Zhang H; Liu Z; Ernst P; Koretzky GA; Hua X
    Cancer Cell; 2010 Feb; 17(2):148-59. PubMed ID: 20159607
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis.
    Tan J; Jones M; Koseki H; Nakayama M; Muntean AG; Maillard I; Hess JL
    Cancer Cell; 2011 Nov; 20(5):563-75. PubMed ID: 22094252
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ZNF521 Enhances MLL-AF9-Dependent Hematopoietic Stem Cell Transformation in Acute Myeloid Leukemias by Altering the Gene Expression Landscape.
    Chiarella E; Aloisio A; Scicchitano S; Todoerti K; Cosentino EG; Lico D; Neri A; Amodio N; Bond HM; Mesuraca M
    Int J Mol Sci; 2021 Oct; 22(19):. PubMed ID: 34639154
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MLL-AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny.
    Horton SJ; Jaques J; Woolthuis C; van Dijk J; Mesuraca M; Huls G; Morrone G; Vellenga E; Schuringa JJ
    Leukemia; 2013 Apr; 27(5):1116-26. PubMed ID: 23178754
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusion target expression and leukemic transformation.
    Ropa J; Saha N; Hu H; Peterson LF; Talpaz M; Muntean AG
    Haematologica; 2020 Sep; 105(9):2273-2285. PubMed ID: 33054052
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis.
    Dobson CL; Warren AJ; Pannell R; Forster A; Lavenir I; Corral J; Smith AJ; Rabbitts TH
    EMBO J; 1999 Jul; 18(13):3564-74. PubMed ID: 10393173
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.
    Jo SY; Granowicz EM; Maillard I; Thomas D; Hess JL
    Blood; 2011 May; 117(18):4759-68. PubMed ID: 21398221
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeted down-regulation of MLL-AF9 with antisense oligodeoxyribonucleotide reduces the expression of the HOXA7 and -A10 genes and induces apoptosis in a human leukemia cell line, THP-1.
    Kawagoe H; Kawagoe R; Sano K
    Leukemia; 2001 Nov; 15(11):1743-9. PubMed ID: 11681416
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model.
    Bergerson RJ; Collier LS; Sarver AL; Been RA; Lugthart S; Diers MD; Zuber J; Rappaport AR; Nixon MJ; Silverstein KA; Fan D; Lamblin AF; Wolff L; Kersey JH; Delwel R; Lowe SW; O'Sullivan MG; Kogan SC; Adams DJ; Largaespada DA
    Blood; 2012 May; 119(19):4512-23. PubMed ID: 22427200
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.
    Chen Y; Jones KL; Anastassiadis K; Kranz A; Stewart AF; Grembecka J; Meyerson M; Ernst P
    Exp Hematol; 2019 Jan; 69():37-42. PubMed ID: 30315824
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CRISPR Gene Editing of Murine Blood Stem and Progenitor Cells Induces MLL-AF9 Chromosomal Translocation and MLL-AF9 Leukaemogenesis.
    Sarrou E; Richmond L; Carmody RJ; Gibson B; Keeshan K
    Int J Mol Sci; 2020 Jun; 21(12):. PubMed ID: 32549410
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease.
    Li Z; Chen P; Su R; Hu C; Li Y; Elkahloun AG; Zuo Z; Gurbuxani S; Arnovitz S; Weng H; Wang Y; Li S; Huang H; Neilly MB; Wang GG; Jiang X; Liu PP; Jin J; Chen J
    Cancer Res; 2016 Feb; 76(3):619-29. PubMed ID: 26747896
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mouse Af9 is a controller of embryo patterning, like Mll, whose human homologue fuses with Af9 after chromosomal translocation in leukemia.
    Collins EC; Appert A; Ariza-McNaughton L; Pannell R; Yamada Y; Rabbitts TH
    Mol Cell Biol; 2002 Oct; 22(20):7313-24. PubMed ID: 12242306
    [TBL] [Abstract][Full Text] [Related]  

  • 16. EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs.
    Bindels EM; Havermans M; Lugthart S; Erpelinck C; Wocjtowicz E; Krivtsov AV; Rombouts E; Armstrong SA; Taskesen E; Haanstra JR; Beverloo HB; Döhner H; Hudson WA; Kersey JH; Delwel R; Kumar AR
    Blood; 2012 Jun; 119(24):5838-49. PubMed ID: 22553314
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The AAA+ ATPase RUVBL2 is a critical mediator of MLL-AF9 oncogenesis.
    Osaki H; Walf-Vorderwülbecke V; Mangolini M; Zhao L; Horton SJ; Morrone G; Schuringa JJ; de Boer J; Williams O
    Leukemia; 2013 Jul; 27(7):1461-8. PubMed ID: 23403462
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia.
    Germano G; Morello G; Aveic S; Pinazza M; Minuzzo S; Frasson C; Persano L; Bonvini P; Viola G; Bresolin S; Tregnago C; Paganin M; Pigazzi M; Indraccolo S; Basso G
    Oncotarget; 2017 Apr; 8(16):26129-26141. PubMed ID: 28412727
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hematopoietic transformation in the absence of MLL1/KMT2A: distinctions in target gene reactivation.
    Chen Y; Ernst P
    Cell Cycle; 2019 Jul; 18(14):1525-1531. PubMed ID: 31161857
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The PHD fingers of MLL block MLL fusion protein-mediated transformation.
    Muntean AG; Giannola D; Udager AM; Hess JL
    Blood; 2008 Dec; 112(12):4690-3. PubMed ID: 18796627
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.