These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 30003621)

  • 1. Orthogonal γPNA Dimerization Domains Empower DNA Binders with Cooperativity and Versatility Mimicking that of Transcription Factor Pairs.
    Yu Z; Hsieh WC; Asamitsu S; Hashiya K; Bando T; Ly DH; Sugiyama H
    Chemistry; 2018 Sep; 24(53):14183-14188. PubMed ID: 30003621
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pip-HoGu: An Artificial Assembly with Cooperative DNA Recognition Capable of Mimicking Transcription Factor Pairs.
    Yu Z; Guo C; Wei Y; Hashiya K; Bando T; Sugiyama H
    J Am Chem Soc; 2018 Feb; 140(7):2426-2429. PubMed ID: 29393635
    [TBL] [Abstract][Full Text] [Related]  

  • 3. G-Quadruplex Induction by the Hairpin Pyrrole-Imidazole Polyamide Dimer.
    Obata S; Asamitsu S; Hashiya K; Bando T; Sugiyama H
    Biochemistry; 2018 Feb; 57(5):498-502. PubMed ID: 29236465
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of the N-terminal acylamido group of imidazole- and pyrrole-containing polyamides on DNA sequence specificity and binding affinity.
    Westrate L; Mackay H; Brown T; Nguyen B; Kluza J; Wilson WD; Lee M; Hartley JA
    Biochemistry; 2009 Jun; 48(24):5679-88. PubMed ID: 19419200
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sequence specific and high affinity recognition of 5'-ACGCGT-3' by rationally designed pyrrole-imidazole H-pin polyamides: thermodynamic and structural studies.
    Mackay H; Brown T; Uthe PB; Westrate L; Sielaff A; Jones J; Lajiness JP; Kluza J; O'Hare C; Nguyen B; Davis Z; Bruce C; Wilson WD; Hartley JA; Lee M
    Bioorg Med Chem; 2008 Oct; 16(20):9145-53. PubMed ID: 18819814
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and DNA binding characteristics of a group of orthogonally positioned diamino, N-formamido, pyrrole- and imidazole-containing polyamides.
    Chavda S; Babu B; Patil P; Plaunt A; Ferguson A; Lee M; Tzou S; Sjoholm R; Rice T; Mackay H; Ramos J; Wang S; Lin S; Kiakos K; Wilson WD; Hartley JA; Lee M
    Bioorg Med Chem; 2013 Jul; 21(13):3907-18. PubMed ID: 23647824
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hx, a novel fluorescent, minor groove and sequence specific recognition element: design, synthesis, and DNA binding properties of p-anisylbenzimidazole-imidazole/pyrrole-containing polyamides.
    Chavda S; Liu Y; Babu B; Davis R; Sielaff A; Ruprich J; Westrate L; Tronrud C; Ferguson A; Franks A; Tzou S; Adkins C; Rice T; Mackay H; Kluza J; Tahir SA; Lin S; Kiakos K; Bruce CD; Wilson WD; Hartley JA; Lee M
    Biochemistry; 2011 Apr; 50(15):3127-36. PubMed ID: 21388229
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The application of fluorescence-conjugated pyrrole/imidazole polyamides in the characterization of protein-DNA complex formation.
    Han YW; Sugiyama H; Harada Y
    Biomater Sci; 2016 Mar; 4(3):391-9. PubMed ID: 26734690
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Next-generation sequencing studies guide the design of pyrrole-imidazole polyamides with improved binding specificity by the addition of β-alanine.
    Anandhakumar C; Li Y; Kizaki S; Pandian GN; Hashiya K; Bando T; Sugiyama H
    Chembiochem; 2014 Dec; 15(18):2647-51. PubMed ID: 25371287
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sequence-specific DNA recognition by cyclic pyrrole-imidazole cysteine-derived polyamide dimers.
    Yamamoto M; Bando T; Morinaga H; Kawamoto Y; Hashiya K; Sugiyama H
    Chemistry; 2014 Jan; 20(3):752-9. PubMed ID: 24339258
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-terminal Cationic Modification of Linear Pyrrole-Imidazole Polyamide Improves Its Binding to DNA.
    Hatanaka J; Hirose Y; Hashiya K; Bando T; Sugiyama H
    Chembiochem; 2022 Jul; 23(14):e202200124. PubMed ID: 35599232
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting the inverted CCAAT box 2 in the topoisomerase IIalpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: design, synthesis, molecular biology, and biophysical studies.
    Henry JA; Le NM; Nguyen B; Howard CM; Bailey SL; Horick SM; Buchmueller KL; Kotecha M; Hochhauser D; Hartley JA; Wilson WD; Lee M
    Biochemistry; 2004 Sep; 43(38):12249-57. PubMed ID: 15379563
    [TBL] [Abstract][Full Text] [Related]  

  • 13. On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides.
    White S; Baird EE; Dervan PB
    Chem Biol; 1997 Aug; 4(8):569-78. PubMed ID: 9281524
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chemical Approaches to the Development of Artificial Transcription Factors Based on Pyrrole-Imidazole Polyamides.
    Hidaka T; Sugiyama H
    Chem Rec; 2021 Jun; 21(6):1374-1384. PubMed ID: 33332727
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sequence recognition in the minor groove of DNA by covalently linked formamido imidazole-pyrrole-imidazole polyamides: effect of H-pin linkage and linker length on selectivity and affinity.
    O'Hare CC; Uthe P; Mackay H; Blackmon K; Jones J; Brown T; Nguyen B; Wilson WD; Lee M; Hartley JA
    Biochemistry; 2007 Oct; 46(42):11661-70. PubMed ID: 17910471
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Strand invasion of extended, mixed-sequence B-DNA by gammaPNAs.
    He G; Rapireddy S; Bahal R; Sahu B; Ly DH
    J Am Chem Soc; 2009 Sep; 131(34):12088-90. PubMed ID: 19663424
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Extending the language of DNA molecular recognition by polyamides: unexpected influence of imidazole and pyrrole arrangement on binding affinity and specificity.
    Buchmueller KL; Staples AM; Howard CM; Horick SM; Uthe PB; Le NM; Cox KK; Nguyen B; Pacheco KA; Wilson WD; Lee M
    J Am Chem Soc; 2005 Jan; 127(2):742-50. PubMed ID: 15643900
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pyrrole-imidazole polyamides distinguish between double-helical DNA and RNA.
    Chenoweth DM; Meier JL; Dervan PB
    Angew Chem Int Ed Engl; 2013 Jan; 52(1):415-8. PubMed ID: 22987334
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of single pyrrole replacement with β-alanine on DNA binding affinity and sequence specificity of hairpin pyrrole/imidazole polyamides targeting 5'-GCGC-3'.
    Han YW; Kashiwazaki G; Morinaga H; Matsumoto T; Hashiya K; Bando T; Harada Y; Sugiyama H
    Bioorg Med Chem; 2013 Sep; 21(17):5436-41. PubMed ID: 23810670
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Conjugation of peptide nucleic acid with a pyrrole/imidazole polyamide to specifically recognize and cleave DNA.
    Kameshima W; Ishizuka T; Minoshima M; Yamamoto M; Sugiyama H; Xu Y; Komiyama M
    Angew Chem Int Ed Engl; 2013 Dec; 52(51):13681-4. PubMed ID: 24155125
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.