BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

256 related articles for article (PubMed ID: 30007118)

  • 1. Small molecule targeting the Rac1-NOX2 interaction prevents collagen-related peptide and thrombin-induced reactive oxygen species generation and platelet activation.
    Akbar H; Duan X; Piatt R; Saleem S; Davis AK; Tandon NN; Bergmeier W; Zheng Y
    J Thromb Haemost; 2018 Oct; 16(10):2083-2096. PubMed ID: 30007118
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential Roles of the NADPH-Oxidase 1 and 2 in Platelet Activation and Thrombosis.
    Delaney MK; Kim K; Estevez B; Xu Z; Stojanovic-Terpo A; Shen B; Ushio-Fukai M; Cho J; Du X
    Arterioscler Thromb Vasc Biol; 2016 May; 36(5):846-54. PubMed ID: 26988594
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of Nox1 and Nox2 in GPVI-dependent platelet activation and thrombus formation.
    Walsh TG; Berndt MC; Carrim N; Cowman J; Kenny D; Metharom P
    Redox Biol; 2014; 2():178-86. PubMed ID: 24494191
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gene targeting implicates Cdc42 GTPase in GPVI and non-GPVI mediated platelet filopodia formation, secretion and aggregation.
    Akbar H; Shang X; Perveen R; Berryman M; Funk K; Johnson JF; Tandon NN; Zheng Y
    PLoS One; 2011; 6(7):e22117. PubMed ID: 21789221
    [TBL] [Abstract][Full Text] [Related]  

  • 5. NADPH oxidase 2 (NOX2): A key target of oxidative stress-mediated platelet activation and thrombosis.
    Fuentes E; Gibbins JM; Holbrook LM; Palomo I
    Trends Cardiovasc Med; 2018 Oct; 28(7):429-434. PubMed ID: 29661712
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Arachidonic acid induces direct interaction of the p67(phox)-Rac complex with the phagocyte oxidase Nox2, leading to superoxide production.
    Matono R; Miyano K; Kiyohara T; Sumimoto H
    J Biol Chem; 2014 Sep; 289(36):24874-84. PubMed ID: 25056956
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The anti-platelet effects of apocynin in mice are not mediated by inhibition of NADPH oxidase activity.
    Dharmarajah J; Arthur JF; Sobey CG; Drummond GR
    Naunyn Schmiedebergs Arch Pharmacol; 2010 Oct; 382(4):377-84. PubMed ID: 20809239
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetic and pharmacologic evidence that Rac1 GTPase is involved in regulation of platelet secretion and aggregation.
    Akbar H; Kim J; Funk K; Cancelas JA; Shang X; Chen L; Johnson JF; Williams DA; Zheng Y
    J Thromb Haemost; 2007 Aug; 5(8):1747-55. PubMed ID: 17663742
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TIAM1-RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy.
    Kowluru RA; Kowluru A; Veluthakal R; Mohammad G; Syed I; Santos JM; Mishra M
    Diabetologia; 2014 May; 57(5):1047-56. PubMed ID: 24554007
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RhoA and Rac1 GTPases Differentially Regulate Agonist-Receptor Mediated Reactive Oxygen Species Generation in Platelets.
    Akbar H; Duan X; Saleem S; Davis AK; Zheng Y
    PLoS One; 2016; 11(9):e0163227. PubMed ID: 27681226
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacologic targeting of Cdc42 GTPase by a small molecule Cdc42 activity-specific inhibitor prevents platelet activation and thrombosis.
    Duan X; Perveen R; Dandamudi A; Adili R; Johnson J; Funk K; Berryman M; Davis AK; Holinstat M; Zheng Y; Akbar H
    Sci Rep; 2021 Jun; 11(1):13170. PubMed ID: 34162972
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets.
    Dütting S; Heidenreich J; Cherpokova D; Amin E; Zhang SC; Ahmadian MR; Brakebusch C; Nieswandt B
    J Thromb Haemost; 2015 May; 13(5):827-38. PubMed ID: 25628054
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The molecular basis of Rac-GTP action-promoting binding of p67
    Bechor E; Zahavi A; Berdichevsky Y; Pick E
    J Leukoc Biol; 2021 Aug; 110(2):219-237. PubMed ID: 33857329
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation.
    Delaney MK; Liu J; Zheng Y; Berndt MC; Du X
    Arterioscler Thromb Vasc Biol; 2012 Nov; 32(11):2761-8. PubMed ID: 22995516
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reelin Amplifies Glycoprotein VI Activation and AlphaIIb Beta3 Integrin Outside-In Signaling via PLC Gamma 2 and Rho GTPases.
    Krueger I; Gremer L; Mangels L; Klier M; Jurk K; Willbold D; Bock HH; Elvers M
    Arterioscler Thromb Vasc Biol; 2020 Oct; 40(10):2391-2403. PubMed ID: 32787521
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nox2 NADPH oxidase is dispensable for platelet activation or arterial thrombosis in mice.
    Sonkar VK; Kumar R; Jensen M; Wagner BA; Sharathkumar AA; Miller FJ; Fasano M; Lentz SR; Buettner GR; Dayal S
    Blood Adv; 2019 Apr; 3(8):1272-1284. PubMed ID: 30995985
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The novel NOX inhibitor 2-acetylphenothiazine impairs collagen-dependent thrombus formation in a GPVI-dependent manner.
    Vara D; Campanella M; Pula G
    Br J Pharmacol; 2013 Jan; 168(1):212-24. PubMed ID: 22881838
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque.
    Dwivedi S; Pandey D; Khandoga AL; Brandl R; Siess W
    J Transl Med; 2010 Dec; 8():128. PubMed ID: 21134286
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rapid Upregulation of Orai1 Abundance in the Plasma Membrane of Platelets Following Activation with Thrombin and Collagen Related Peptide.
    Liu G; Liu G; Chen H; Alzoubi K; Umbach AT; Gawaz M; Stournaras C; Lang F
    Cell Physiol Biochem; 2015; 37(5):1759-66. PubMed ID: 26584277
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphatidylinositol 3-kinase-dependent membrane recruitment of Rac-1 and p47phox is critical for alpha-platelet-derived growth factor receptor-induced production of reactive oxygen species.
    Bäumer AT; Ten Freyhaus H; Sauer H; Wartenberg M; Kappert K; Schnabel P; Konkol C; Hescheler J; Vantler M; Rosenkranz S
    J Biol Chem; 2008 Mar; 283(12):7864-76. PubMed ID: 18070887
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.