BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 30008477)

  • 1. The MCL1-specific inhibitor S63845 acts synergistically with venetoclax/ABT-199 to induce apoptosis in T-cell acute lymphoblastic leukemia cells.
    Li Z; He S; Look AT
    Leukemia; 2019 Jan; 33(1):262-266. PubMed ID: 30008477
    [No Abstract]   [Full Text] [Related]  

  • 2. Pairing MCL-1 inhibition with venetoclax improves therapeutic efficiency of BH3-mimetics in AML.
    Hormi M; Birsen R; Belhadj M; Huynh T; Cantero Aguilar L; Grignano E; Haddaoui L; Guillonneau F; Mayeux P; Hunault M; Tamburini J; Kosmider O; Fontenay M; Bouscary D; Chapuis N
    Eur J Haematol; 2020 Nov; 105(5):588-596. PubMed ID: 32659848
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Venetoclax, bortezomib and S63845, an MCL1 inhibitor, in multiple myeloma.
    Wong KY; Chim CS
    J Pharm Pharmacol; 2020 May; 72(5):728-737. PubMed ID: 32066201
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss.
    He S; Zimmerman MW; Layden HM; Berezovskaya A; Etchin J; Martel MW; Thurston G; Jing CB; van Rooijen E; Kaufman CK; Rodig SJ; Zon LI; Patton EE; Mansour MR; Look AT
    Oncogene; 2021 Sep; 40(38):5718-5729. PubMed ID: 34331013
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cotargeting of BCL2 with Venetoclax and MCL1 with S63845 Is Synthetically Lethal
    Prukova D; Andera L; Nahacka Z; Karolova J; Svaton M; Klanova M; Havranek O; Soukup J; Svobodova K; Zemanova Z; Tuskova D; Pokorna E; Helman K; Forsterova K; Pacheco-Blanco M; Vockova P; Berkova A; Fronkova E; Trneny M; Klener P
    Clin Cancer Res; 2019 Jul; 25(14):4455-4465. PubMed ID: 31004002
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting BCL-2 and ABL/LYN in Philadelphia chromosome-positive acute lymphoblastic leukemia.
    Leonard JT; Rowley JS; Eide CA; Traer E; Hayes-Lattin B; Loriaux M; Spurgeon SE; Druker BJ; Tyner JW; Chang BH
    Sci Transl Med; 2016 Aug; 8(354):354ra114. PubMed ID: 27582059
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tumor-targeted nanoparticles improve the therapeutic index of BCL2 and MCL1 dual inhibition.
    Bala Tannan N; Manzari MT; Herviou L; Da Silva Ferreira M; Hagen C; Kiguchi H; Manova-Todorova K; Seshan V; de Stanchina E; Heller DA; Younes A
    Blood; 2021 Apr; 137(15):2057-2069. PubMed ID: 33067607
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Feasibility of the Combination of Venetoclax and Asparaginase-based Chemotherapy for Adult Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia.
    El-Cheikh J; Moukalled NM; El Darsa H; Massoud R; Kanj SS; Mahfouz R; Bazarbachi A
    Clin Lymphoma Myeloma Leuk; 2018 Oct; 18(10):e441-e444. PubMed ID: 30166258
    [No Abstract]   [Full Text] [Related]  

  • 9. Antitumor action of CDK inhibitor LS-007 as a single agent and in combination with ABT-199 against human acute leukemia cells.
    Xie S; Jiang H; Zhai XW; Wei F; Wang SD; Ding J; Chen Y
    Acta Pharmacol Sin; 2016 Nov; 37(11):1481-1489. PubMed ID: 27569395
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1.
    Teh TC; Nguyen NY; Moujalled DM; Segal D; Pomilio G; Rijal S; Jabbour A; Cummins K; Lackovic K; Blombery P; Thompson E; Ekert PG; Lessene G; Glaser SP; Huang DCS; Roberts AW; Guthridge MA; Wei AH
    Leukemia; 2018 Feb; 32(2):303-312. PubMed ID: 28751770
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibiting casein kinase 2 sensitizes acute lymphoblastic leukemia cells to venetoclax via MCL1 degradation.
    Lázaro-Navarro J; Pimentel-Gutiérrez HJ; Gauert A; Hagemann AIH; Eisenschmid J; Gökbuget N; Vick B; Jeremias I; Seyfried F; Meyer LH; Debatin KM; Richer K; Bultman M; Neumann M; Hänzelmann S; Serve H; Astrahantseff K; Rieger MA; Eckert C; Baldus CD; Bastian L
    Blood Adv; 2021 Dec; 5(24):5501-5506. PubMed ID: 34610112
    [No Abstract]   [Full Text] [Related]  

  • 12. A new chemotherapy-free regimen of olverembatinib in combination with venetoclax and dexamethasone for newly diagnosed Ph+ acute lymphoblastic leukemia: Preliminary outcomes of a prospective study.
    Tang H; Jia W; Jia S; Dong R; Gao S; Feng J; Dong H; Gu H; Zhang T; Yuan R; Liu X; Cheng L; Zhou S; Gao G
    Am J Hematol; 2024 Jun; 99(6):1177-1179. PubMed ID: 38482543
    [No Abstract]   [Full Text] [Related]  

  • 13. Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia.
    Peirs S; Frismantas V; Matthijssens F; Van Loocke W; Pieters T; Vandamme N; Lintermans B; Dobay MP; Berx G; Poppe B; Goossens S; Bornhauser BC; Bourquin JP; Van Vlierberghe P
    Leukemia; 2017 Oct; 31(10):2037-2047. PubMed ID: 28074072
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Flavopiridol enhances ABT-199 sensitivity in unfavourable-risk multiple myeloma cells in vitro and in vivo.
    Zhou L; Zhang Y; Sampath D; Leverson J; Dai Y; Kmieciak M; Nguyen M; Orlowski RZ; Grant S
    Br J Cancer; 2018 Feb; 118(3):388-397. PubMed ID: 29241222
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Superior anti-tumor activity of the MDM2 antagonist idasanutlin and the Bcl-2 inhibitor venetoclax in p53 wild-type acute myeloid leukemia models.
    Lehmann C; Friess T; Birzele F; Kiialainen A; Dangl M
    J Hematol Oncol; 2016 Jun; 9(1):50. PubMed ID: 27353420
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models.
    Kotschy A; Szlavik Z; Murray J; Davidson J; Maragno AL; Le Toumelin-Braizat G; Chanrion M; Kelly GL; Gong JN; Moujalled DM; Bruno A; Csekei M; Paczal A; Szabo ZB; Sipos S; Radics G; Proszenyak A; Balint B; Ondi L; Blasko G; Robertson A; Surgenor A; Dokurno P; Chen I; Matassova N; Smith J; Pedder C; Graham C; Studeny A; Lysiak-Auvity G; Girard AM; Gravé F; Segal D; Riffkin CD; Pomilio G; Galbraith LC; Aubrey BJ; Brennan MS; Herold MJ; Chang C; Guasconi G; Cauquil N; Melchiore F; Guigal-Stephan N; Lockhart B; Colland F; Hickman JA; Roberts AW; Huang DC; Wei AH; Strasser A; Lessene G; Geneste O
    Nature; 2016 Oct; 538(7626):477-482. PubMed ID: 27760111
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia.
    Iacovelli S; Ricciardi MR; Allegretti M; Mirabilii S; Licchetta R; Bergamo P; Rinaldo C; Zeuner A; Foà R; Milella M; McCubrey JA; Martelli AM; Tafuri A
    Oncotarget; 2015 Oct; 6(31):32089-103. PubMed ID: 26392332
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Venetoclax and Decitabine in Pediatric Refractory T-cell Lymphoblastic Lymphoma.
    Baig MU; Rytting M; Roth M; Morani AC; Nunez C; Lin P; Cuglievan B
    J Pediatr Hematol Oncol; 2021 Oct; 43(7):e991-e996. PubMed ID: 33480649
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Co-operation of ABT-199 and gemcitabine in impeding DNA damage repair and inducing cell apoptosis for synergistic therapy of T-cell acute lymphoblastic leukemia.
    Xiufeng Z; Haijun Z; Silei B; Manman D; Yong Z; Lian Y; Zhihong F; Bing X
    Anticancer Drugs; 2019 Feb; 30(2):138-148. PubMed ID: 30320607
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Venetoclax-ponatinib for T315I/compound-mutated Ph+ acute lymphoblastic leukemia.
    Wang H; Yang C; Shi T; Zhang Y; Qian J; Wang Y; Hu Y; Mao L; Ye X; Liu F; Xi Z; Shou L; Fu C; Naranmandura H; Jin J; Zhu HH
    Blood Cancer J; 2022 Jan; 12(1):20. PubMed ID: 35091541
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 13.