256 related articles for article (PubMed ID: 30009856)
21. Targeting pyruvate kinase M2 contributes to radiosensitivity of non-small cell lung cancer cells in vitro and in vivo.
Meng MB; Wang HH; Guo WH; Wu ZQ; Zeng XL; Zaorsky NG; Shi HS; Qian D; Niu ZM; Jiang B; Zhao LJ; Yuan ZY; Wang P
Cancer Lett; 2015 Jan; 356(2 Pt B):985-93. PubMed ID: 25444918
[TBL] [Abstract][Full Text] [Related]
22. Pyruvate kinase M2 facilitates colon cancer cell migration via the modulation of STAT3 signalling.
Yang P; Li Z; Fu R; Wu H; Li Z
Cell Signal; 2014 Sep; 26(9):1853-62. PubMed ID: 24686087
[TBL] [Abstract][Full Text] [Related]
23. Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth.
Hitosugi T; Kang S; Vander Heiden MG; Chung TW; Elf S; Lythgoe K; Dong S; Lonial S; Wang X; Chen GZ; Xie J; Gu TL; Polakiewicz RD; Roesel JL; Boggon TJ; Khuri FR; Gilliland DG; Cantley LC; Kaufman J; Chen J
Sci Signal; 2009 Nov; 2(97):ra73. PubMed ID: 19920251
[TBL] [Abstract][Full Text] [Related]
24. Protein kinase C epsilon promotes de novo lipogenesis and tumor growth in prostate cancer cells by regulating the phosphorylation and nuclear translocation of pyruvate kinase isoform M2.
Lai X; Liang Y; Jin J; Zhang H; Wu Z; Li G; Wang J; Zhang Z; Chen H; Zeng F; Deng F
Exp Cell Res; 2023 Jan; 422(1):113427. PubMed ID: 36400183
[TBL] [Abstract][Full Text] [Related]
25. Identification of Parthenolide Dimers as Activators of Pyruvate Kinase M2 in Xenografts of Glioblastoma Multiforme in Vivo.
Ding Y; Xue Q; Liu S; Hu K; Wang D; Wang T; Li Y; Guo H; Hao X; Ge W; Zhang Y; Li A; Li J; Chen Y; Zhang Q
J Med Chem; 2020 Feb; 63(4):1597-1611. PubMed ID: 31977207
[TBL] [Abstract][Full Text] [Related]
26. Pyruvate kinase M2 is a poor prognostic marker of and a therapeutic target in ovarian cancer.
Chao TK; Huang TS; Liao YP; Huang RL; Su PH; Shen HY; Lai HC; Wang YC
PLoS One; 2017; 12(7):e0182166. PubMed ID: 28753677
[TBL] [Abstract][Full Text] [Related]
27. Reciprocal regulation of protein kinase and pyruvate kinase activities of pyruvate kinase M2 by growth signals.
Gao X; Wang H; Yang JJ; Chen J; Jie J; Li L; Zhang Y; Liu ZR
J Biol Chem; 2013 May; 288(22):15971-9. PubMed ID: 23576436
[TBL] [Abstract][Full Text] [Related]
28. Pyruvate kinase type M2 is upregulated in colorectal cancer and promotes proliferation and migration of colon cancer cells.
Zhou CF; Li XB; Sun H; Zhang B; Han YS; Jiang Y; Zhuang QL; Fang J; Wu GH
IUBMB Life; 2012 Sep; 64(9):775-82. PubMed ID: 22807066
[TBL] [Abstract][Full Text] [Related]
29. Efficacy of RNAi targeting of pyruvate kinase M2 combined with cisplatin in a lung cancer model.
Guo W; Zhang Y; Chen T; Wang Y; Xue J; Zhang Y; Xiao W; Mo X; Lu Y
J Cancer Res Clin Oncol; 2011 Jan; 137(1):65-72. PubMed ID: 20336315
[TBL] [Abstract][Full Text] [Related]
30. New pyridin-3-ylmethyl carbamodithioic esters activate pyruvate kinase M2 and potential anticancer lead compounds.
Zhang Y; Liu B; Wu X; Li R; Ning X; Liu Y; Liu Z; Ge Z; Li R; Yin Y
Bioorg Med Chem; 2015 Aug; 23(15):4815-4823. PubMed ID: 26081759
[TBL] [Abstract][Full Text] [Related]
31. Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.
Lv L; Li D; Zhao D; Lin R; Chu Y; Zhang H; Zha Z; Liu Y; Li Z; Xu Y; Wang G; Huang Y; Xiong Y; Guan KL; Lei QY
Mol Cell; 2011 Jun; 42(6):719-30. PubMed ID: 21700219
[TBL] [Abstract][Full Text] [Related]
32. Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread.
Giannoni E; Taddei ML; Morandi A; Comito G; Calvani M; Bianchini F; Richichi B; Raugei G; Wong N; Tang D; Chiarugi P
Oncotarget; 2015 Sep; 6(27):24061-74. PubMed ID: 26183399
[TBL] [Abstract][Full Text] [Related]
33. Subcellular compartmentalization of PKM2 identifies anti-PKM2 therapy response in vitro and in vivo mouse model of human non-small-cell lung cancer.
Suzuki A; Puri S; Leland P; Puri A; Moudgil T; Fox BA; Puri RK; Joshi BH
PLoS One; 2019; 14(5):e0217131. PubMed ID: 31120964
[TBL] [Abstract][Full Text] [Related]
34. Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells.
Shin DS; Kim HN; Shin KD; Yoon YJ; Kim SJ; Han DC; Kwon BM
Cancer Res; 2009 Jan; 69(1):193-202. PubMed ID: 19118003
[TBL] [Abstract][Full Text] [Related]
35. Inhibition of Pyruvate Kinase M2 Markedly Reduces Chemoresistance of Advanced Bladder Cancer to Cisplatin.
Wang X; Zhang F; Wu XR
Sci Rep; 2017 Apr; 7():45983. PubMed ID: 28378811
[TBL] [Abstract][Full Text] [Related]
36. Pyruvate kinase M2 and cancer: an updated assessment.
Iqbal MA; Gupta V; Gopinath P; Mazurek S; Bamezai RN
FEBS Lett; 2014 Aug; 588(16):2685-92. PubMed ID: 24747424
[TBL] [Abstract][Full Text] [Related]
37. Succinylation-dependent mitochondrial translocation of PKM2 promotes cell survival in response to nutritional stress.
Qi H; Ning X; Yu C; Ji X; Jin Y; McNutt MA; Yin Y
Cell Death Dis; 2019 Feb; 10(3):170. PubMed ID: 30787272
[TBL] [Abstract][Full Text] [Related]
38. Knockdown of the M2 Isoform of Pyruvate Kinase (PKM2) with shRNA Enhances the Effect of Docetaxel in Human NSCLC Cell Lines In Vitro.
Yuan S; Qiao T; Zhuang X; Chen W; Xing N; Zhang Q
Yonsei Med J; 2016 Nov; 57(6):1312-23. PubMed ID: 27593857
[TBL] [Abstract][Full Text] [Related]
39. Synthesis and antitumor activity of novel 2, 3-didithiocarbamate substituted naphthoquinones as inhibitors of pyruvate kinase M2 isoform.
Ning X; Qi H; Li R; Jin Y; McNutt MA; Yin Y
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):126-129. PubMed ID: 29185365
[TBL] [Abstract][Full Text] [Related]
40. AKT2 contributes to increase ovarian cancer cell migration and invasion through the AKT2-PKM2-STAT3/NF-κB axis.
Zheng B; Geng L; Zeng L; Liu F; Huang Q
Cell Signal; 2018 May; 45():122-131. PubMed ID: 29374601
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
