BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

356 related articles for article (PubMed ID: 30011940)

  • 21. TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.
    Gómez-Herreros F; Romero-Granados R; Zeng Z; Alvarez-Quilón A; Quintero C; Ju L; Umans L; Vermeire L; Huylebroeck D; Caldecott KW; Cortés-Ledesma F
    PLoS Genet; 2013; 9(3):e1003226. PubMed ID: 23505375
    [TBL] [Abstract][Full Text] [Related]  

  • 22. TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage.
    Zeng Z; Cortés-Ledesma F; El Khamisy SF; Caldecott KW
    J Biol Chem; 2011 Jan; 286(1):403-9. PubMed ID: 21030584
    [TBL] [Abstract][Full Text] [Related]  

  • 23. SUMO-Targeted DNA Translocase Rrp2 Protects the Genome from Top2-Induced DNA Damage.
    Wei Y; Diao LX; Lu S; Wang HT; Suo F; Dong MQ; Du LL
    Mol Cell; 2017 Jun; 66(5):581-596.e6. PubMed ID: 28552615
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Novel TDP2-ubiquitin interactions and their importance for the repair of topoisomerase II-mediated DNA damage.
    Rao T; Gao R; Takada S; Al Abo M; Chen X; Walters KJ; Pommier Y; Aihara H
    Nucleic Acids Res; 2016 Dec; 44(21):10201-10215. PubMed ID: 27543075
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Proteasomal inhibition potentiates drugs targeting DNA topoisomerase II.
    Lee KC; Bramley RL; Cowell IG; Jackson GH; Austin CA
    Biochem Pharmacol; 2016 Mar; 103():29-39. PubMed ID: 26794000
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Physiological concentrations of glucocorticoids induce pathological DNA double-strand breaks.
    Akter S; Shimba A; Ikuta K; Mahmud MRA; Yamada S; Sasanuma H; Tsuda M; Sone M; Ago Y; Murai K; Tanaka H; Takeda S
    Genes Cells; 2023 Jan; 28(1):53-67. PubMed ID: 36415926
    [TBL] [Abstract][Full Text] [Related]  

  • 27. RAD54L2 counters TOP2-DNA adducts to promote genome stability.
    D'Alessandro G; Morales-Juarez DA; Richards SL; Nitiss KC; Serrano-Benitez A; Wang J; Thomas JC; Gupta V; Voigt A; Belotserkovskaya R; Goh CG; Bowden AR; Galanty Y; Beli P; Nitiss JL; Zagnoli-Vieira G; Jackson SP
    Sci Adv; 2023 Dec; 9(49):eadl2108. PubMed ID: 38055822
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Untangling trapped topoisomerases with tyrosyl-DNA phosphodiesterases.
    Zagnoli-Vieira G; Caldecott KW
    DNA Repair (Amst); 2020 Oct; 94():102900. PubMed ID: 32653827
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity.
    Sciascia N; Wu W; Zong D; Sun Y; Wong N; John S; Wangsa D; Ried T; Bunting SF; Pommier Y; Nussenzweig A
    Elife; 2020 Feb; 9():. PubMed ID: 32057297
    [TBL] [Abstract][Full Text] [Related]  

  • 30. TDP2, TOP2, and SUMO: what is ZATT about?
    Zagnoli-Vieira G; Caldecott KW
    Cell Res; 2017 Dec; 27(12):1405-1406. PubMed ID: 29160298
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage.
    Cortes Ledesma F; El Khamisy SF; Zuma MC; Osborn K; Caldecott KW
    Nature; 2009 Oct; 461(7264):674-8. PubMed ID: 19794497
    [TBL] [Abstract][Full Text] [Related]  

  • 32. TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.
    Zeng Z; Sharma A; Ju L; Murai J; Umans L; Vermeire L; Pommier Y; Takeda S; Huylebroeck D; Caldecott KW; El-Khamisy SF
    Nucleic Acids Res; 2012 Sep; 40(17):8371-80. PubMed ID: 22740648
    [TBL] [Abstract][Full Text] [Related]  

  • 33. MRN, CtIP, and BRCA1 mediate repair of topoisomerase II-DNA adducts.
    Aparicio T; Baer R; Gottesman M; Gautier J
    J Cell Biol; 2016 Feb; 212(4):399-408. PubMed ID: 26880199
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2.
    Schellenberg MJ; Appel CD; Riccio AA; Butler LR; Krahn JM; Liebermann JA; Cortés-Ledesma F; Williams RS
    Nucleic Acids Res; 2020 Jun; 48(11):6310-6325. PubMed ID: 32356875
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Differential and common DNA repair pathways for topoisomerase I- and II-targeted drugs in a genetic DT40 repair cell screen panel.
    Maede Y; Shimizu H; Fukushima T; Kogame T; Nakamura T; Miki T; Takeda S; Pommier Y; Murai J
    Mol Cancer Ther; 2014 Jan; 13(1):214-20. PubMed ID: 24130054
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Biochemical characterization of human tyrosyl-DNA phosphodiesterase 2 (TDP2/TTRAP): a Mg(2+)/Mn(2+)-dependent phosphodiesterase specific for the repair of topoisomerase cleavage complexes.
    Gao R; Huang SY; Marchand C; Pommier Y
    J Biol Chem; 2012 Aug; 287(36):30842-52. PubMed ID: 22822062
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Deazaflavin Inhibitors of TDP2 with Cellular Activity Can Affect Etoposide Influx and/or Efflux.
    Komulainen E; Pennicott L; Le Grand D; Caldecott KW
    ACS Chem Biol; 2019 Jun; 14(6):1110-1114. PubMed ID: 31091068
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Inactivating TDP2 missense mutation in siblings with congenital abnormalities reminiscent of fanconi anemia.
    Zagnoli-Vieira G; Brazina J; Van Den Bogaert K; Huybrechts W; Molenaers G; Caldecott KW; Van Esch H
    Hum Genet; 2023 Sep; 142(9):1417-1427. PubMed ID: 37558815
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The retinoblastoma tumor suppressor protein is required for efficient processing and repair of trapped topoisomerase II-DNA-cleavable complexes.
    Xiao H; Goodrich DW
    Oncogene; 2005 Dec; 24(55):8105-13. PubMed ID: 16091739
    [TBL] [Abstract][Full Text] [Related]  

  • 40. DNA double-strand breaks with 5' adducts are efficiently channeled to the DNA2-mediated resection pathway.
    Tammaro M; Liao S; Beeharry N; Yan H
    Nucleic Acids Res; 2016 Jan; 44(1):221-31. PubMed ID: 26420828
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 18.