319 related articles for article (PubMed ID: 30014490)
1. Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma.
Bárcena-Varela M; Caruso S; Llerena S; Álvarez-Sola G; Uriarte I; Latasa MU; Urtasun R; Rebouissou S; Alvarez L; Jimenez M; Santamaría E; Rodriguez-Ortigosa C; Mazza G; Rombouts K; San José-Eneriz E; Rabal O; Agirre X; Iraburu M; Santos-Laso A; Banales JM; Zucman-Rossi J; Prósper F; Oyarzabal J; Berasain C; Ávila MA; Fernández-Barrena MG
Hepatology; 2019 Feb; 69(2):587-603. PubMed ID: 30014490
[TBL] [Abstract][Full Text] [Related]
2. Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma.
Colyn L; Bárcena-Varela M; Álvarez-Sola G; Latasa MU; Uriarte I; Santamaría E; Herranz JM; Santos-Laso A; Arechederra M; Ruiz de Gauna M; Aspichueta P; Canale M; Casadei-Gardini A; Francesconi M; Carotti S; Morini S; Nelson LJ; Iraburu MJ; Chen C; Sangro B; Marin JJG; Martinez-Chantar ML; Banales JM; Arnes-Benito R; Huch M; Patino JM; Dar AA; Nosrati M; Oyarzábal J; Prósper F; Urman J; Cubero FJ; Trautwein C; Berasain C; Fernandez-Barrena MG; Avila MA
Hepatology; 2021 Jun; 73(6):2380-2396. PubMed ID: 33222246
[TBL] [Abstract][Full Text] [Related]
3. Histone methyltransferase G9a promotes liver cancer development by epigenetic silencing of tumor suppressor gene RARRES3.
Wei L; Chiu DK; Tsang FH; Law CT; Cheng CL; Au SL; Lee JM; Wong CC; Ng IO; Wong CM
J Hepatol; 2017 Oct; 67(4):758-769. PubMed ID: 28532996
[TBL] [Abstract][Full Text] [Related]
4. Circ ubiquitin-like-containing plant homeodomain and RING finger domains protein 1 increases the stability of G9a and ubiquitin-like-containing plant homeodomain and RING finger domains protein 1 messenger RNA through recruiting eukaryotic translation initiation factor 4A3, transcriptionally inhibiting PDZ and homeobox protein domain protein 1, and promotes the metastasis of hepatocellular carcinoma.
Huang X; Zhou LZ; Feng WJ; Liu YQ; Chen M; Tang LY; Gan ZY; Zhang P
J Gastroenterol Hepatol; 2024 Mar; 39(3):596-607. PubMed ID: 38059880
[TBL] [Abstract][Full Text] [Related]
5. Targeting G9a/DNMT1 methyltransferase activity impedes IGF2-mediated survival in hepatoblastoma.
Demir S; Razizadeh N; Indersie E; Branchereau S; Cairo S; Kappler R
Hepatol Commun; 2024 Feb; 8(2):. PubMed ID: 38285887
[TBL] [Abstract][Full Text] [Related]
6. Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis.
Barcena-Varela M; Paish H; Alvarez L; Uriarte I; Latasa MU; Santamaria E; Recalde M; Garate M; Claveria A; Colyn L; Arechederra M; Iraburu MJ; Milkiewicz M; Milkiewicz P; Sangro B; Robinson SM; French J; Pardo-Saganta A; Oyarzabal J; Prosper F; Rombouts K; Oakley F; Mann J; Berasain C; Avila MA; G Fernandez-Barrena M
Gut; 2021 Feb; 70(2):388-400. PubMed ID: 32327527
[TBL] [Abstract][Full Text] [Related]
7. Histone lysine methyltransferase G9a is a novel epigenetic target for the treatment of hepatocellular carcinoma.
Yokoyama M; Chiba T; Zen Y; Oshima M; Kusakabe Y; Noguchi Y; Yuki K; Koide S; Tara S; Saraya A; Aoyama K; Mimura N; Miyagi S; Inoue M; Wakamatsu T; Saito T; Ogasawara S; Suzuki E; Ooka Y; Tawada A; Otsuka M; Miyazaki M; Yokosuka O; Iwama A
Oncotarget; 2017 Mar; 8(13):21315-21326. PubMed ID: 28423509
[TBL] [Abstract][Full Text] [Related]
8. Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with
Rabal O; San José-Enériz E; Agirre X; Sánchez-Arias JA; de Miguel I; Ordoñez R; Garate L; Miranda E; Sáez E; Vilas-Zornoza A; Pineda-Lucena A; Estella A; Zhang F; Wu W; Xu M; Prosper F; Oyarzabal J
J Med Chem; 2021 Mar; 64(6):3392-3426. PubMed ID: 33661013
[TBL] [Abstract][Full Text] [Related]
9. Cross-talk Between Histone and DNA Methylation Mediates Bone Loss in Hind Limb Unloading.
Li B; Zhao J; Ma J; Chen W; Zhou C; Wei W; Li S; Li G; Xin G; Zhang Y; Liu J; Wang Y; Ma X
J Bone Miner Res; 2021 May; 36(5):956-967. PubMed ID: 33465813
[TBL] [Abstract][Full Text] [Related]
10. UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells.
Kim JK; Estève PO; Jacobsen SE; Pradhan S
Nucleic Acids Res; 2009 Feb; 37(2):493-505. PubMed ID: 19056828
[TBL] [Abstract][Full Text] [Related]
11. Thymoquinone Is a Multitarget Single Epidrug That Inhibits the UHRF1 Protein Complex.
Abdullah O; Omran Z; Hosawi S; Hamiche A; Bronner C; Alhosin M
Genes (Basel); 2021 Apr; 12(5):. PubMed ID: 33922029
[TBL] [Abstract][Full Text] [Related]
12. The novel mTOR inhibitor Torin-2 induces autophagy and downregulates the expression of UHRF1 to suppress hepatocarcinoma cell growth.
Wang C; Wang X; Su Z; Fei H; Liu X; Pan Q
Oncol Rep; 2015 Oct; 34(4):1708-16. PubMed ID: 26239364
[TBL] [Abstract][Full Text] [Related]
13. Transcription factor LSF-DNMT1 complex dissociation by FQI1 leads to aberrant DNA methylation and gene expression.
Chin HG; Ponnaluri VK; Zhang G; Estève PO; Schaus SE; Hansen U; Pradhan S
Oncotarget; 2016 Dec; 7(50):83627-83640. PubMed ID: 27845898
[TBL] [Abstract][Full Text] [Related]
14. The aberrant expression of MEG3 regulated by UHRF1 predicts the prognosis of hepatocellular carcinoma.
Zhuo H; Tang J; Lin Z; Jiang R; Zhang X; Ji J; Wang P; Sun B
Mol Carcinog; 2016 Feb; 55(2):209-19. PubMed ID: 25641194
[TBL] [Abstract][Full Text] [Related]
15. UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer.
Jin W; Chen L; Chen Y; Xu SG; Di GH; Yin WJ; Wu J; Shao ZM
Breast Cancer Res Treat; 2010 Sep; 123(2):359-73. PubMed ID: 19943104
[TBL] [Abstract][Full Text] [Related]
16. Targeting histone methyltransferase G9a inhibits growth and Wnt signaling pathway by epigenetically regulating HP1α and APC2 gene expression in non-small cell lung cancer.
Zhang K; Wang J; Yang L; Yuan YC; Tong TR; Wu J; Yun X; Bonner M; Pangeni R; Liu Z; Yuchi T; Kim JY; Raz DJ
Mol Cancer; 2018 Oct; 17(1):153. PubMed ID: 30348169
[TBL] [Abstract][Full Text] [Related]
17. Histone-lysine N-methyltransferase EHMT2 (G9a) inhibition mitigates tumorigenicity in Myc-driven liver cancer.
Thng DKH; Hooi L; Toh CCM; Lim JJ; Rajagopalan D; Syariff IQC; Tan ZM; Rashid MBMA; Zhou L; Kow AWC; Bonney GK; Goh BKP; Kam JH; Jha S; Dan YY; Chow PKH; Toh TB; Chow EK
Mol Oncol; 2023 Nov; 17(11):2275-2294. PubMed ID: 36896891
[TBL] [Abstract][Full Text] [Related]
18. LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex.
Duvall-Noelle N; Karwandyar A; Richmond A; Raman D
Oncogene; 2016 Mar; 35(9):1122-33. PubMed ID: 25982273
[TBL] [Abstract][Full Text] [Related]
19. The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence.
Jung HJ; Byun HO; Jee BA; Min S; Jeoun UW; Lee YK; Seo Y; Woo HG; Yoon G
J Biol Chem; 2017 Mar; 292(9):3729-3739. PubMed ID: 28100769
[TBL] [Abstract][Full Text] [Related]
20. SET8 prevents excessive DNA methylation by methylation-mediated degradation of UHRF1 and DNMT1.
Zhang H; Gao Q; Tan S; You J; Lyu C; Zhang Y; Han M; Chen Z; Li J; Wang H; Liao L; Qin J; Li J; Wong J
Nucleic Acids Res; 2019 Sep; 47(17):9053-9068. PubMed ID: 31400111
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
