BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

269 related articles for article (PubMed ID: 30016076)

  • 1. Analyzing 2000 in Vivo Drug Delivery Data Points Reveals Cholesterol Structure Impacts Nanoparticle Delivery.
    Paunovska K; Gil CJ; Lokugamage MP; Sago CD; Sato M; Lando GN; Gamboa Castro M; Bryksin AV; Dahlman JE
    ACS Nano; 2018 Aug; 12(8):8341-8349. PubMed ID: 30016076
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation.
    Paunovska K; Sago CD; Monaco CM; Hudson WH; Castro MG; Rudoltz TG; Kalathoor S; Vanover DA; Santangelo PJ; Ahmed R; Bryksin AV; Dahlman JE
    Nano Lett; 2018 Mar; 18(3):2148-2157. PubMed ID: 29489381
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nanoparticles That Deliver RNA to Bone Marrow Identified by in Vivo Directed Evolution.
    Sago CD; Lokugamage MP; Islam FZ; Krupczak BR; Sato M; Dahlman JE
    J Am Chem Soc; 2018 Dec; 140(49):17095-17105. PubMed ID: 30394729
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nanoparticles Containing Oxidized Cholesterol Deliver mRNA to the Liver Microenvironment at Clinically Relevant Doses.
    Paunovska K; Da Silva Sanchez AJ; Sago CD; Gan Z; Lokugamage MP; Islam FZ; Kalathoor S; Krupczak BR; Dahlman JE
    Adv Mater; 2019 Apr; 31(14):e1807748. PubMed ID: 30748040
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Constrained Nanoparticles Deliver siRNA and sgRNA to T Cells In Vivo without Targeting Ligands.
    Lokugamage MP; Sago CD; Gan Z; Krupczak BR; Dahlman JE
    Adv Mater; 2019 Oct; 31(41):e1902251. PubMed ID: 31465135
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing.
    Sago CD; Lokugamage MP; Paunovska K; Vanover DA; Monaco CM; Shah NN; Gamboa Castro M; Anderson SE; Rudoltz TG; Lando GN; Munnilal Tiwari P; Kirschman JL; Willett N; Jang YC; Santangelo PJ; Bryksin AV; Dahlman JE
    Proc Natl Acad Sci U S A; 2018 Oct; 115(42):E9944-E9952. PubMed ID: 30275336
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Universal Barcoding Predicts
    Da Silva Sanchez AJ; Dobrowolski C; Cristian A; Echeverri ES; Zhao K; Hatit MZC; Loughrey D; Paunovska K; Dahlman JE
    Nano Lett; 2022 Jun; 22(12):4822-4830. PubMed ID: 35671473
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design of Peptidomimetic Functionalized Cholesterol Based Lipid Nanoparticles for Efficient Delivery of Therapeutic Nucleic Acids.
    Ehexige E; Ganbold T; Yu X; Han S; Baigude H
    Molecules; 2019 Sep; 24(18):. PubMed ID: 31546908
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantitation of physiological and biochemical barriers to siRNA liver delivery via lipid nanoparticle platform.
    Xu Y; Ou M; Keough E; Roberts J; Koeplinger K; Lyman M; Fauty S; Carlini E; Stern M; Zhang R; Yeh S; Mahan E; Wang Y; Slaughter D; Gindy M; Raab C; Thompson C; Hochman J
    Mol Pharm; 2014 May; 11(5):1424-34. PubMed ID: 24588618
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening.
    Guimaraes PPG; Zhang R; Spektor R; Tan M; Chung A; Billingsley MM; El-Mayta R; Riley RS; Wang L; Wilson JM; Mitchell MJ
    J Control Release; 2019 Dec; 316():404-417. PubMed ID: 31678653
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modifying a Commonly Expressed Endocytic Receptor Retargets Nanoparticles in Vivo.
    Sago CD; Lokugamage MP; Lando GN; Djeddar N; Shah NN; Syed C; Bryksin AV; Dahlman JE
    Nano Lett; 2018 Dec; 18(12):7590-7600. PubMed ID: 30216729
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of a Microfluidic-Based Post-Treatment Process for Size-Controlled Lipid Nanoparticles and Application to siRNA Delivery.
    Kimura N; Maeki M; Sato Y; Ishida A; Tani H; Harashima H; Tokeshi M
    ACS Appl Mater Interfaces; 2020 Jul; 12(30):34011-34020. PubMed ID: 32667806
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative analysis of lipid Nanoparticle-Mediated delivery of CRISPR-Cas9 RNP versus mRNA/sgRNA for gene editing in vitro and in vivo.
    Walther J; Porenta D; Wilbie D; Seinen C; Benne N; Yang Q; de Jong OG; Lei Z; Mastrobattista E
    Eur J Pharm Biopharm; 2024 Mar; 196():114207. PubMed ID: 38325664
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure, activity and uptake mechanism of siRNA-lipid nanoparticles with an asymmetric ionizable lipid.
    Suzuki Y; Ishihara H
    Int J Pharm; 2016 Aug; 510(1):350-8. PubMed ID: 27374199
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lipid Nanoparticle (LNP) Chemistry Can Endow Unique
    Johnson LT; Zhang D; Zhou K; Lee SM; Liu S; Dilliard SA; Farbiak L; Chatterjee S; Lin YH; Siegwart DJ
    Mol Pharm; 2022 Nov; 19(11):3973-3986. PubMed ID: 36154076
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lipid Nanoparticle Formulations for Enhanced Co-delivery of siRNA and mRNA.
    Ball RL; Hajj KA; Vizelman J; Bajaj P; Whitehead KA
    Nano Lett; 2018 Jun; 18(6):3814-3822. PubMed ID: 29694050
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Extent to Which Lipid Nanoparticles Require Apolipoprotein E and Low-Density Lipoprotein Receptor for Delivery Changes with Ionizable Lipid Structure.
    Paunovska K; Da Silva Sanchez AJ; Lokugamage MP; Loughrey D; Echeverri ES; Cristian A; Hatit MZC; Santangelo PJ; Zhao K; Dahlman JE
    Nano Lett; 2022 Dec; 22(24):10025-10033. PubMed ID: 36521071
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Helper lipid structure influences protein adsorption and delivery of lipid nanoparticles to spleen and liver.
    Zhang R; El-Mayta R; Murdoch TJ; Warzecha CC; Billingsley MM; Shepherd SJ; Gong N; Wang L; Wilson JM; Lee D; Mitchell MJ
    Biomater Sci; 2021 Feb; 9(4):1449-1463. PubMed ID: 33404020
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Highly specific delivery of siRNA to hepatocytes circumvents endothelial cell-mediated lipid nanoparticle-associated toxicity leading to the safe and efficacious decrease in the hepatitis B virus.
    Sato Y; Matsui H; Yamamoto N; Sato R; Munakata T; Kohara M; Harashima H
    J Control Release; 2017 Nov; 266():216-225. PubMed ID: 28986168
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Substituting racemic ionizable lipids with stereopure ionizable lipids can increase mRNA delivery.
    Da Silva Sanchez AJ; Zhao K; Huayamares SG; Hatit MZC; Lokugamage MP; Loughrey D; Dobrowolski C; Wang S; Kim H; Paunovska K; Kuzminich Y; Dahlman JE
    J Control Release; 2023 Jan; 353():270-277. PubMed ID: 36423872
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.