290 related articles for article (PubMed ID: 30018141)
1. GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3Kγ/PREX1 signaling and T cell cytokine secretion.
Dinkel BA; Kremer KN; Rollins MR; Medlyn MJ; Hedin KE
J Biol Chem; 2018 Sep; 293(36):14022-14039. PubMed ID: 30018141
[TBL] [Abstract][Full Text] [Related]
2. TCR-CXCR4 signaling stabilizes cytokine mRNA transcripts via a PREX1-Rac1 pathway: implications for CTCL.
Kremer KN; Dinkel BA; Sterner RM; Osborne DG; Jevremovic D; Hedin KE
Blood; 2017 Aug; 130(8):982-994. PubMed ID: 28694325
[TBL] [Abstract][Full Text] [Related]
3. Stromal cell-derived factor-1 signaling via the CXCR4-TCR heterodimer requires phospholipase C-β3 and phospholipase C-γ1 for distinct cellular responses.
Kremer KN; Clift IC; Miamen AG; Bamidele AO; Qian NX; Humphreys TD; Hedin KE
J Immunol; 2011 Aug; 187(3):1440-7. PubMed ID: 21705626
[TBL] [Abstract][Full Text] [Related]
4. PREX1 Protein Function Is Negatively Regulated Downstream of Receptor Tyrosine Kinase Activation by p21-activated Kinases (PAKs).
Barrows D; He JZ; Parsons R
J Biol Chem; 2016 Sep; 291(38):20042-54. PubMed ID: 27481946
[TBL] [Abstract][Full Text] [Related]
5. Identification of upregulated phosphoinositide 3-kinase γ as a target to suppress breast cancer cell migration and invasion.
Xie Y; Abel PW; Kirui JK; Deng C; Sharma P; Wolff DW; Toews ML; Tu Y
Biochem Pharmacol; 2013 May; 85(10):1454-62. PubMed ID: 23500535
[TBL] [Abstract][Full Text] [Related]
6. Endocytosis is required for C
English EJ; Mahn SA; Marchese A
J Biol Chem; 2018 Jul; 293(29):11470-11480. PubMed ID: 29899118
[TBL] [Abstract][Full Text] [Related]
7. Atypical Chemokine Receptor 3 "Senses" CXC Chemokine Receptor 4 Activation Through GPCR Kinase Phosphorylation.
Schafer CT; Chen Q; Tesmer JJG; Handel TM
Mol Pharmacol; 2023 Oct; 104(4):174-186. PubMed ID: 37474305
[TBL] [Abstract][Full Text] [Related]
8. Physiological changes in GRK2 regulate CCL2-induced signaling to ERK1/2 and Akt but not to MEK1/2 and calcium.
Kleibeuker W; Jurado-Pueyo M; Murga C; Eijkelkamp N; Mayor F; Heijnen CJ; Kavelaars A
J Neurochem; 2008 Feb; 104(4):979-92. PubMed ID: 17971124
[TBL] [Abstract][Full Text] [Related]
9. TCR activation inhibits chemotaxis toward stromal cell-derived factor-1: evidence for reciprocal regulation between CXCR4 and the TCR.
Peacock JW; Jirik FR
J Immunol; 1999 Jan; 162(1):215-23. PubMed ID: 9886389
[TBL] [Abstract][Full Text] [Related]
10. TCR and CD28 are coupled via ZAP-70 to the activation of the Vav/Rac-1-/PAK-1/p38 MAPK signaling pathway.
Salojin KV; Zhang J; Delovitch TL
J Immunol; 1999 Jul; 163(2):844-53. PubMed ID: 10395678
[TBL] [Abstract][Full Text] [Related]
11. PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling.
Liu HJ; Ooms LM; Srijakotre N; Man J; Vieusseux J; Waters JE; Feng Y; Bailey CG; Rasko JE; Price JT; Mitchell CA
J Biol Chem; 2016 Aug; 291(33):17258-70. PubMed ID: 27358402
[TBL] [Abstract][Full Text] [Related]
12. Paeoniflorin-6'-O-benzene sulfonate down-regulates CXCR4-Gβγ-PI3K/AKT mediated migration in fibroblast-like synoviocytes of rheumatoid arthritis by inhibiting GRK2 translocation.
Wang DD; Jiang MY; Wang W; Zhou WJ; Zhang YW; Yang M; Chen JY; Wei W
Biochem Biophys Res Commun; 2020 Jun; 526(3):805-812. PubMed ID: 32268958
[TBL] [Abstract][Full Text] [Related]
13. CXCR4 physically associates with the T cell receptor to signal in T cells.
Kumar A; Humphreys TD; Kremer KN; Bramati PS; Bradfield L; Edgar CE; Hedin KE
Immunity; 2006 Aug; 25(2):213-24. PubMed ID: 16919488
[TBL] [Abstract][Full Text] [Related]
14. The endosomal sorting complex required for transport pathway mediates chemokine receptor CXCR4-promoted lysosomal degradation of the mammalian target of rapamycin antagonist DEPTOR.
Verma R; Marchese A
J Biol Chem; 2015 Mar; 290(11):6810-24. PubMed ID: 25605718
[TBL] [Abstract][Full Text] [Related]
15. Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling.
Busillo JM; Armando S; Sengupta R; Meucci O; Bouvier M; Benovic JL
J Biol Chem; 2010 Mar; 285(10):7805-17. PubMed ID: 20048153
[TBL] [Abstract][Full Text] [Related]
16. G alpha i2 and ZAP-70 mediate RasGRP1 membrane localization and activation of SDF-1-induced T cell functions.
Kremer KN; Kumar A; Hedin KE
J Immunol; 2011 Sep; 187(6):3177-85. PubMed ID: 21856938
[TBL] [Abstract][Full Text] [Related]
17. PI3Kγ kinase activity is required for optimal T-cell activation and differentiation.
Ladygina N; Gottipati S; Ngo K; Castro G; Ma JY; Banie H; Rao TS; Fung-Leung WP
Eur J Immunol; 2013 Dec; 43(12):3183-96. PubMed ID: 24030559
[TBL] [Abstract][Full Text] [Related]
18. G protein-coupled receptor kinase 2 negatively regulates chemokine signaling at a level downstream from G protein subunits.
Jiménez-Sainz MC; Murga C; Kavelaars A; Jurado-Pueyo M; Krakstad BF; Heijnen CJ; Mayor F; Aragay AM
Mol Biol Cell; 2006 Jan; 17(1):25-31. PubMed ID: 16221891
[TBL] [Abstract][Full Text] [Related]
19. G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton.
Cant SH; Pitcher JA
Mol Biol Cell; 2005 Jul; 16(7):3088-99. PubMed ID: 15843435
[TBL] [Abstract][Full Text] [Related]
20. G protein βγ translocation to the Golgi apparatus activates MAPK via p110γ-p101 heterodimers.
Khater M; Wei Z; Xu X; Huang W; Lokeshwar BL; Lambert NA; Wu G
J Biol Chem; 2021; 296():100325. PubMed ID: 33493514
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
