189 related articles for article (PubMed ID: 30023819)
1. Drug-Clinical Agent Molecular Hybrid: Synthesis of Diaryl(trifluoromethyl)pyrazoles as Tubulin Targeting Anticancer Agents.
Hura N; Naaz A; Prassanawar SS; Guchhait SK; Panda D
ACS Omega; 2018 Feb; 3(2):1955-1969. PubMed ID: 30023819
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors.
Romagnoli R; Oliva P; Salvador MK; Camacho ME; Padroni C; Brancale A; Ferla S; Hamel E; Ronca R; Grillo E; Bortolozzi R; Rruga F; Mariotto E; Viola G
Eur J Med Chem; 2019 Nov; 181():111577. PubMed ID: 31400707
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and Biological Evaluation of 3-Alkyl-1,5-Diaryl-1H-Pyrazoles as Rigid Analogues of Combretastatin A-4 with Potent Antiproliferative Activity.
Xu Q; Qi H; Sun M; Zuo D; Jiang X; Wen Z; Wang Z; Wu Y; Zhang W
PLoS One; 2015; 10(6):e0128710. PubMed ID: 26061410
[TBL] [Abstract][Full Text] [Related]
4. Novel Combretastatin-2-aminoimidazole Analogues as Potent Tubulin Assembly Inhibitors: Exploration of Unique Pharmacophoric Impact of Bridging Skeleton and Aryl Moiety.
Chaudhary V; Venghateri JB; Dhaked HP; Bhoyar AS; Guchhait SK; Panda D
J Med Chem; 2016 Apr; 59(7):3439-51. PubMed ID: 26938120
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of New N
Elmeligie S; Khalil NA; Ahmed EM; Emam SH; Zaitone SA
Biol Pharm Bull; 2016; 39(10):1611-1622. PubMed ID: 27725438
[TBL] [Abstract][Full Text] [Related]
6. Combretastatin-Inspired Heterocycles as Antitubulin Anticancer Agents.
Hura N; Sawant AV; Kumari A; Guchhait SK; Panda D
ACS Omega; 2018 Aug; 3(8):9754-9769. PubMed ID: 31459105
[TBL] [Abstract][Full Text] [Related]
7. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
Romagnoli R; Kimatrai Salvador M; Schiaffino Ortega S; Baraldi PG; Oliva P; Baraldi S; Lopez-Cara LC; Brancale A; Ferla S; Hamel E; Balzarini J; Liekens S; Mattiuzzo E; Basso G; Viola G
Eur J Med Chem; 2018 Jan; 143():683-698. PubMed ID: 29220790
[TBL] [Abstract][Full Text] [Related]
8. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
Liu YN; Wang JJ; Ji YT; Zhao GD; Tang LQ; Zhang CM; Guo XL; Liu ZP
J Med Chem; 2016 Jun; 59(11):5341-55. PubMed ID: 27172319
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
Lai Q; Wang Y; Wang R; Lai W; Tang L; Tao Y; Liu Y; Zhang R; Huang L; Xiang H; Zeng S; Gou L; Chen H; Yao Y; Yang J
Eur J Med Chem; 2018 Aug; 156():162-179. PubMed ID: 30006162
[TBL] [Abstract][Full Text] [Related]
10. Hybridization of the Pharmacophoric Features of Discoipyrrole C and Combretastatin A-4 toward New Anticancer Leads.
Kurian J; Ashtam A; Kesavan A; Chaluvalappil SV; Panda D; Manheri MK
ChemMedChem; 2023 Aug; 18(16):e202300081. PubMed ID: 37256820
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
Zhou P; Liang Y; Zhang H; Jiang H; Feng K; Xu P; Wang J; Wang X; Ding K; Luo C; Liu M; Wang Y
Eur J Med Chem; 2018 Jan; 144():817-842. PubMed ID: 29306206
[TBL] [Abstract][Full Text] [Related]
12. Chemical synthesis, pharmacological evaluation and in silico analysis of new 2,3,3a,4,5,6-hexahydrocyclopenta[c]pyrazole derivatives as potential anti-mitotic agents.
Minu M; Singh D; Mahaddalkar T; Lopus M; Winter P; Ayoub AT; Missiaen K; Tilli TM; Pasdar M; Tuszynski J
Bioorg Med Chem Lett; 2016 Aug; 26(16):3855-61. PubMed ID: 27449957
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, cytotoxic evaluation and molecular docking study of 2-alkylthio-4-(2,3,4-trimethoxyphenyl)-5-aryl-thiazoles as tubulin polymerization inhibitors.
Salehi M; Amini M; Ostad SN; Riazi GH; Assadieskandar A; Shafiei B; Shafiee A
Bioorg Med Chem; 2013 Dec; 21(24):7648-54. PubMed ID: 24238904
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
Stefański T; Mikstacka R; Kurczab R; Dutkiewicz Z; Kucińska M; Murias M; Zielińska-Przyjemska M; Cichocki M; Teubert A; Kaczmarek M; Hogendorf A; Sobiak S
Eur J Med Chem; 2018 Jan; 144():797-816. PubMed ID: 29291446
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and Antiproliferative Evaluation of 3-Chloroazetidin-2-ones with Antimitotic Activity: Heterocyclic Bridged Analogues of Combretastatin A-4.
Malebari AM; Wang S; Greene TF; O'Boyle NM; Fayne D; Khan MF; Nathwani SM; Twamley B; McCabe T; Zisterer DM; Meegan MJ
Pharmaceuticals (Basel); 2021 Oct; 14(11):. PubMed ID: 34832901
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
Cushman M; Nagarathnam D; Gopal D; Chakraborti AK; Lin CM; Hamel E
J Med Chem; 1991 Aug; 34(8):2579-88. PubMed ID: 1875350
[TBL] [Abstract][Full Text] [Related]
17. Copper-Catalyzed Syntheses of Pyrene-Pyrazole Pharmacophores and Structure Activity Studies for Tubulin Polymerization.
Sar D; Srivastava I; Misra SK; Ostadhossein F; Fathi P; Pan D
ACS Omega; 2018 Jun; 3(6):6378-6387. PubMed ID: 30221233
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and Bioevaluation of 3,6-Diaryl-[1,2,4]triazolo[4,3-
Xu Q; Wang Y; Xu J; Sun M; Tian H; Zuo D; Guan Q; Bao K; Wu Y; Zhang W
ACS Med Chem Lett; 2016 Dec; 7(12):1202-1206. PubMed ID: 27994764
[TBL] [Abstract][Full Text] [Related]
19. Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study.
Lin CM; Singh SB; Chu PS; Dempcy RO; Schmidt JM; Pettit GR; Hamel E
Mol Pharmacol; 1988 Aug; 34(2):200-8. PubMed ID: 3412321
[TBL] [Abstract][Full Text] [Related]
20. Identification of novel 1-indolyl acetate-5-nitroimidazole derivatives of combretastatin A-4 as potential tubulin polymerization inhibitors.
Yao YF; Wang ZC; Wu SY; Li QF; Yu C; Liang XY; Lv PC; Duan YT; Zhu HL
Biochem Pharmacol; 2017 Aug; 137():10-28. PubMed ID: 28456516
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
