BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 30024282)

  • 1. Patterns of sensitivity to a panel of drugs are highly individualised for undifferentiated/unclassified soft tissue sarcoma (USTS) in patient-derived orthotopic xenograft (PDOX) nude-mouse models.
    Kawaguchi K; Igarashi K; Miyake K; Kiyuna T; Miyake M; Singh AS; Chmielowski B; Nelson SD; Russell TA; Dry SM; Li Y; Unno M; Singh SR; Eilber FC; Hoffman RM
    J Drug Target; 2019 Feb; 27(2):211-216. PubMed ID: 30024282
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Individualized doxorubicin sensitivity testing of undifferentiated soft tissue sarcoma (USTS) in a patient-derived orthotopic xenograft (PDOX) model demonstrates large differences between patients.
    Kawaguchi K; Igarashi K; Kiyuna T; Miyake K; Miyake M; Murakami T; Chmielowski B; Nelson SD; Russell TA; Dry SM; Li Y; Singh AS; Unno M; Eilber FC; Hoffman RM
    Cell Cycle; 2018; 17(5):627-633. PubMed ID: 29384032
    [TBL] [Abstract][Full Text] [Related]  

  • 3. High Efficacy of Pazopanib on an Undifferentiated Spindle-Cell Sarcoma Resistant to First-Line Therapy Is Identified With a Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model.
    Igarashi K; Kawaguchi K; Murakami T; Kiyuna T; Miyake K; Singh AS; Nelson SD; Dry SM; Li Y; Yamamoto N; Hayashi K; Kimura H; Miwa S; Tsuchiya H; Eilber FC; Hoffman RM
    J Cell Biochem; 2017 Sep; 118(9):2739-2743. PubMed ID: 28176365
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The combination of gemcitabine and nab-paclitaxel as a novel effective treatment strategy for undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.
    Higuchi T; Kawaguchi K; Miyake K; Oshiro H; Zhang Z; Razmjooei S; Wangsiricharoen S; Igarashi K; Yamamoto N; Hayashi K; Kimura H; Miwa S; Nelson SD; Dry SM; Li Y; Chawla SP; Eilber FC; Singh SR; Tsuchiya H; Hoffman RM
    Biomed Pharmacother; 2019 Mar; 111():835-840. PubMed ID: 30616082
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The combination of olaratumab with gemcitabine and docetaxel arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft mouse model.
    Higuchi T; Miyake K; Sugisawa N; Oshiro H; Zhang Z; Razmjooei S; Yamamoto N; Hayashi K; Kimura H; Miwa S; Igarashi K; Bouvet M; Singh SR; Tsuchiya H; Hoffman RM
    Cancer Chemother Pharmacol; 2019 Jun; 83(6):1075-1082. PubMed ID: 30929053
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Temozolomide targets and arrests a doxorubicin-resistant follicular dendritic-cell sarcoma patient-derived orthotopic xenograft mouse model.
    Oshiro H; Tome Y; Kiyuna T; Miyake K; Kawaguchi K; Higuchi T; Miyake M; Zang Z; Razmjooei S; Barangi M; Wangsiricharoen S; Nelson SD; Li Y; Bouvet M; Singh SR; Kanaya F; Hoffman RM
    Tissue Cell; 2019 Jun; 58():17-23. PubMed ID: 31133242
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Olaratumab combined with doxorubicin and ifosfamide overcomes individual doxorubicin and olaratumab resistance of an undifferentiated soft-tissue sarcoma in a PDOX mouse model.
    Higuchi T; Miyake K; Sugisawa N; Oshiro H; Zhang Z; Razmjooei S; Yamamoto N; Hayashi K; Kimura H; Miwa S; Igarashi K; Bouvet M; Singh SR; Tsuchiya H; Hoffman RM
    Cancer Lett; 2019 Jun; 451():122-127. PubMed ID: 30867142
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tumor-targeting Salmonella typhimurium A1-R is a highly effective general therapeutic for undifferentiated soft tissue sarcoma patient-derived orthotopic xenograft nude-mouse models.
    Igarashi K; Kawaguchi K; Kiyuna T; Miyake K; Miyake M; Singh AS; Eckardt MA; Nelson SD; Russell TA; Dry SM; Li Y; Yamamoto N; Hayashi K; Kimura H; Miwa S; Tsuchiya H; Singh SR; Eilber FC; Hoffman RM
    Biochem Biophys Res Commun; 2018 Mar; 497(4):1055-1061. PubMed ID: 29481803
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A patient-derived orthotopic xenograft (PDOX) nude-mouse model precisely identifies effective and ineffective therapies for recurrent leiomyosarcoma.
    Zhang Z; Hu K; Kiyuna T; Miyake K; Kawaguchi K; Igarashi K; Nelson SD; Li Y; Singh SR; Hoffman RM
    Pharmacol Res; 2019 Apr; 142():169-175. PubMed ID: 30807865
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recombinant methioninase in combination with doxorubicin (DOX) overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of undifferentiated spindle-cell sarcoma.
    Igarashi K; Kawaguchi K; Li S; Han Q; Tan Y; Murakami T; Kiyuna T; Miyake K; Miyake M; Singh AS; Eckardt MA; Nelson SD; Russell TA; Dry SM; Li Y; Yamamoto N; Hayashi K; Kimura H; Miwa S; Tsuchiya H; Singh SR; Eilber FC; Hoffman RM
    Cancer Lett; 2018 Mar; 417():168-173. PubMed ID: 29306021
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model.
    Igarashi K; Kawaguchi K; Kiyuna T; Miyake K; Miyake M; Nelson SD; Russell TA; Dry SM; Li Y; Yamamoto N; Hayashi K; Kimura H; Miwa S; Higuchi T; Singh SR; Tsuchiya H; Hoffman RM
    Tissue Cell; 2019 Jun; 58():107-111. PubMed ID: 31133237
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Combination of oral recombinant methioninase and decitabine arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma patient-derived orthotopic xenograft mouse model.
    Higuchi T; Han Q; Miyake K; Oshiro H; Sugisawa N; Tan Y; Yamamoto N; Hayashi K; Kimura H; Miwa S; Igarashi K; Bouvet M; Singh SR; Tsuchiya H; Hoffman RM
    Biochem Biophys Res Commun; 2020 Feb; 523(1):135-139. PubMed ID: 31839218
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Doxorubicin-resistant pleomorphic liposarcoma with PDGFRA gene amplification is targeted and regressed by pazopanib in a patient-derived orthotopic xenograft mouse model.
    Kiyuna T; Murakami T; Tome Y; Igarashi K; Kawaguchi K; Miyake K; Miyake M; Li Y; Nelson SD; Dry SM; Singh AS; Russell TA; Singh SR; Kanaya F; Eilber FC; Hoffman RM
    Tissue Cell; 2018 Aug; 53():30-36. PubMed ID: 30060824
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Temozolomide regresses a doxorubicin-resistant undifferentiated spindle-cell sarcoma patient-derived orthotopic xenograft (PDOX): precision-oncology nude-mouse model matching the patient with effective therapy.
    Igarashi K; Kawaguchi K; Kiyuna T; Miyake K; Miyake M; Li Y; Nelson SD; Dry SM; Singh AS; Elliott IA; Russell TA; Eckardt MA; Yamamoto N; Hayashi K; Kimura H; Miwa S; Tsuchiya H; Eilber FC; Hoffman RM
    J Cell Biochem; 2018 Aug; 119(8):6598-6603. PubMed ID: 29737543
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Growth of doxorubicin-resistant undifferentiated spindle-cell sarcoma PDOX is arrested by metabolic targeting with recombinant methioninase.
    Igarashi K; Li S; Han Q; Tan Y; Kawaguchi K; Murakami T; Kiyuna T; Miyake K; Li Y; Nelson SD; Dry SM; Singh AS; Elliott IA; Russell TA; Eckardt MA; Yamamoto N; Hayashi K; Kimura H; Miwa S; Tsuchiya H; Eilber FC; Hoffman RM
    J Cell Biochem; 2018 Apr; 119(4):3537-3544. PubMed ID: 29143983
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Combination of gemcitabine and docetaxel regresses both gastric leiomyosarcoma proliferation and invasion in an imageable patient-derived orthotopic xenograft (iPDOX) model.
    Kawaguchi K; Igarashi K; Murakami T; Kiyuna T; Nelson SD; Dry SM; Li Y; Russell TA; Singh AS; Chmielowski B; Unno M; Eilber FC; Hoffman RM
    Cell Cycle; 2017 Jun; 16(11):1063-1069. PubMed ID: 28426279
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Eribulin Regresses a Doxorubicin-resistant Dedifferentiated Liposarcoma in a Patient-derived Orthotopic Xenograft Mouse Model.
    Igarashi K; Kawaguchi K; Kiyuna T; Miyake K; Higuchi T; Yamamoto N; Hayashi K; Kimura H; Miwa S; Singh SR; Tsuchiya H; Hoffman RM
    Cancer Genomics Proteomics; 2020; 17(4):351-358. PubMed ID: 32576580
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regorafenib regressed a doxorubicin-resistant Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude mouse model.
    Miyake K; Kiyuna T; Kawaguchi K; Higuchi T; Oshiro H; Zhang Z; Wangsiricharoen S; Razmjooei S; Li Y; Nelson SD; Murakami T; Hiroshima Y; Matsuyama R; Bouvet M; Chawla SP; Singh SR; Endo I; Hoffman RM
    Cancer Chemother Pharmacol; 2019 May; 83(5):809-815. PubMed ID: 30758647
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Eribulin regresses a doxorubicin-resistant Ewing's sarcoma with a FUS-ERG fusion and CDKN2A-deletion in a patient-derived orthotopic xenograft (PDOX) nude mouse model.
    Miyake K; Murakami T; Kiyuna T; Igarashi K; Kawaguchi K; Li Y; Singh AS; Dry SM; Eckardt MA; Hiroshima Y; Momiyama M; Matsuyama R; Chishima T; Endo I; Eilber FC; Hoffman RM
    J Cell Biochem; 2018 Jan; 119(1):967-972. PubMed ID: 28681998
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Labeling the Stroma of a Patient-Derived Orthotopic Xenograft (PDOX) Mouse Model of Undifferentiated Pleomorphic Soft-Tissue Sarcoma With Red Fluorescent Protein for Rapid Non-Invasive Imaging for Drug Screening.
    Kiyuna T; Murakami T; Tome Y; Igarashi K; Kawaguchi K; Russell T; Eckardt MA; Crompton J; Singh A; Bernthal N; Bukata S; Federman N; Kanaya F; Eilber FC; Hoffman RM
    J Cell Biochem; 2017 Feb; 118(2):361-365. PubMed ID: 27357060
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.