157 related articles for article (PubMed ID: 30025350)
1. Design, synthesis and screening of 1, 2, 4-triazinone derivatives as potential antitumor agents with apoptosis inducing activity on MCF-7 breast cancer cell line.
Zaki I; Abdelhameid MK; El-Deen IM; Abdel Wahab AHA; Ashmawy AM; Mohamed KO
Eur J Med Chem; 2018 Aug; 156():563-579. PubMed ID: 30025350
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis, and cytotoxicity screening of 5-aryl-3-(2-(pyrrolyl) thiophenyl)-1, 2, 4-oxadiazoles as potential antitumor molecules on breast cancer MCF-7 cells.
Abd El Hameid MK; Mohammed MR
Bioorg Chem; 2019 May; 86():609-623. PubMed ID: 30807934
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents.
Wang ZZ; Sun WX; Wang X; Zhang YH; Qiu HY; Qi JL; Pang YJ; Lu GH; Wang XM; Yu FG; Yang YH
Chem Biol Drug Des; 2017 Aug; 90(2):236-243. PubMed ID: 28079286
[TBL] [Abstract][Full Text] [Related]
4. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
Kassab AE; Gedawy EM
Eur J Med Chem; 2018 Apr; 150():403-418. PubMed ID: 29547830
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and biological evaluation of chromenopyrimidines as potential cytotoxic agents.
El-Bakhshawangy NM; El-Nassan HB; Kassab AE; Taher AT
Future Med Chem; 2018 Jun; 10(12):1465-1481. PubMed ID: 29779400
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
Qin YJ; Li YJ; Jiang AQ; Yang MR; Zhu QZ; Dong H; Zhu HL
Eur J Med Chem; 2015 Apr; 94():447-57. PubMed ID: 25828827
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of a terphenyl substituted 4-aza-2,3-didehydropodophyllotoxin analogues as inhibitors of tubulin polymerization and apoptosis inducers.
Kamal A; Tamboli JR; Nayak VL; Adil SF; Vishnuvardhan MV; Ramakrishna S
Bioorg Med Chem; 2014 May; 22(9):2714-23. PubMed ID: 24721832
[TBL] [Abstract][Full Text] [Related]
8. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.
Zhao W; Chen L; Li HM; Wang DJ; Li DS; Chen T; Yuan ZP; Tang YJ
Bioorg Med Chem; 2014 Jun; 22(11):2998-3007. PubMed ID: 24775914
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis and molecular modeling of new 4-phenylcoumarin derivatives as tubulin polymerization inhibitors targeting MCF-7 breast cancer cells.
Batran RZ; Kassem AF; Abbas EMH; Elseginy SA; Mounier MM
Bioorg Med Chem; 2018 Jul; 26(12):3474-3490. PubMed ID: 29793751
[TBL] [Abstract][Full Text] [Related]
10. 4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
Reddy VG; Bonam SR; Reddy TS; Akunuri R; Naidu VGM; Nayak VL; Bhargava SK; Kumar HMS; Srihari P; Kamal A
Eur J Med Chem; 2018 Jan; 144():595-611. PubMed ID: 29289884
[TBL] [Abstract][Full Text] [Related]
11. Investigation of podophyllotoxin esters as potential anticancer agents: synthesis, biological studies and tubulin inhibition properties.
Shareef MA; Duscharla D; Ramasatyaveni G; Dhoke NR; Das A; Ummanni R; Srivastava AK
Eur J Med Chem; 2015 Jan; 89():128-37. PubMed ID: 25462233
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
Stefański T; Mikstacka R; Kurczab R; Dutkiewicz Z; Kucińska M; Murias M; Zielińska-Przyjemska M; Cichocki M; Teubert A; Kaczmarek M; Hogendorf A; Sobiak S
Eur J Med Chem; 2018 Jan; 144():797-816. PubMed ID: 29291446
[TBL] [Abstract][Full Text] [Related]
13. Design and synthesis of silicon-containing tubulin polymerization inhibitors: replacement of the ethylene moiety of combretastatin A-4 with a silicon linker.
Nakamura M; Kajita D; Matsumoto Y; Hashimoto Y
Bioorg Med Chem; 2013 Dec; 21(23):7381-91. PubMed ID: 24139940
[TBL] [Abstract][Full Text] [Related]
14. Design and synthesis of thienopyrimidine urea derivatives with potential cytotoxic and pro-apoptotic activity against breast cancer cell line MCF-7.
Abdelhaleem EF; Abdelhameid MK; Kassab AE; Kandeel MM
Eur J Med Chem; 2018 Jan; 143():1807-1825. PubMed ID: 29133058
[TBL] [Abstract][Full Text] [Related]
15. Design, Synthesis and Screening of 4,6-Diaryl Pyridine and Pyrimidine Derivatives as Potential Cytotoxic Molecules.
Abd Elhameid MK; Ryad N; Al-Shorbagy MY; Mohammed MR; Ismail MM; El Meligie S
Chem Pharm Bull (Tokyo); 2018 Oct; 66(10):939-952. PubMed ID: 30111667
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and screening of benzimidazole containing compounds with methoxylated aryl radicals as cytotoxic molecules on (HCT-116) colon cancer cells.
Noha RM; Abdelhameid MK; Ismail MM; Mohammed MR; Salwa E
Eur J Med Chem; 2021 Jan; 209():112870. PubMed ID: 33158579
[TBL] [Abstract][Full Text] [Related]
17. Methyl 5-[(1H-indol-3-yl)selanyl]-1H-benzoimidazol-2-ylcarbamate (M-24), a novel tubulin inhibitor, causes G2/M arrest and cell apoptosis by disrupting tubulin polymerization in human cervical and breast cancer cells.
Zuo D; Jiang X; Han M; Shen J; Lang B; Guan Q; Bai Z; Han C; Li Z; Zhang W; Wu Y
Toxicol In Vitro; 2017 Aug; 42():139-149. PubMed ID: 28412508
[TBL] [Abstract][Full Text] [Related]
18. Design, Synthesis, and Screening of 5-Aryl-3-(2-(pyrrolyl)thiophenyl)-1,2,4-oxadiazoles as Potential Antitumor Molecules on Breast Cancer MCF-7 Cell Line.
Abd El Hameid MK
Chem Pharm Bull (Tokyo); 2018 Dec; 66(12):1181-1195. PubMed ID: 30298827
[TBL] [Abstract][Full Text] [Related]
19. New promising levofloxacin derivatives: Design, synthesis, cytotoxic activity screening, Topo2β polymerase inhibition assay, cell cycle apoptosis profile analysis.
El-Malah A; Youssef A; Ismail M; Kamel M; Mahmoud Z
Bioorg Chem; 2021 Aug; 113():105029. PubMed ID: 34091290
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of quinoline analogues of flavones as potential anticancer agents and tubulin polymerization inhibitors.
Shobeiri N; Rashedi M; Mosaffa F; Zarghi A; Ghandadi M; Ghasemi A; Ghodsi R
Eur J Med Chem; 2016 May; 114():14-23. PubMed ID: 26974371
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
