BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

277 related articles for article (PubMed ID: 30026309)

  • 1. Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling.
    Hrdinka M; Schlicher L; Dai B; Pinkas DM; Bufton JC; Picaud S; Ward JA; Rogers C; Suebsuwong C; Nikhar S; Cuny GD; Huber KV; Filippakopoulos P; Bullock AN; Degterev A; Gyrd-Hansen M
    EMBO J; 2018 Sep; 37(17):. PubMed ID: 30026309
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A regulatory region on RIPK2 is required for XIAP binding and NOD signaling activity.
    Heim VJ; Dagley LF; Stafford CA; Hansen FM; Clayer E; Bankovacki A; Webb AI; Lucet IS; Silke J; Nachbur U
    EMBO Rep; 2020 Nov; 21(11):e50400. PubMed ID: 32954645
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling.
    Goncharov T; Hedayati S; Mulvihill MM; Izrael-Tomasevic A; Zobel K; Jeet S; Fedorova AV; Eidenschenk C; deVoss J; Yu K; Shaw AS; Kirkpatrick DS; Fairbrother WJ; Deshayes K; Vucic D
    Mol Cell; 2018 Feb; 69(4):551-565.e7. PubMed ID: 29452636
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity.
    Damgaard RB; Nachbur U; Yabal M; Wong WW; Fiil BK; Kastirr M; Rieser E; Rickard JA; Bankovacki A; Peschel C; Ruland J; Bekker-Jensen S; Mailand N; Kaufmann T; Strasser A; Walczak H; Silke J; Jost PJ; Gyrd-Hansen M
    Mol Cell; 2012 Jun; 46(6):746-58. PubMed ID: 22607974
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors.
    Canning P; Ruan Q; Schwerd T; Hrdinka M; Maki JL; Saleh D; Suebsuwong C; Ray S; Brennan PE; Cuny GD; Uhlig HH; Gyrd-Hansen M; Degterev A; Bullock AN
    Chem Biol; 2015 Sep; 22(9):1174-84. PubMed ID: 26320862
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling.
    Damgaard RB; Fiil BK; Speckmann C; Yabal M; zur Stadt U; Bekker-Jensen S; Jost PJ; Ehl S; Mailand N; Gyrd-Hansen M
    EMBO Mol Med; 2013 Aug; 5(8):1278-95. PubMed ID: 23818254
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design of pyrido[2,3-d]pyrimidin-7-one inhibitors of receptor interacting protein kinase-2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling.
    Nikhar S; Siokas I; Schlicher L; Lee S; Gyrd-Hansen M; Degterev A; Cuny GD
    Eur J Med Chem; 2021 Apr; 215():113252. PubMed ID: 33601309
    [TBL] [Abstract][Full Text] [Related]  

  • 8. XIAP mediates NOD signaling via interaction with RIP2.
    Krieg A; Correa RG; Garrison JB; Le Negrate G; Welsh K; Huang Z; Knoefel WT; Reed JC
    Proc Natl Acad Sci U S A; 2009 Aug; 106(34):14524-9. PubMed ID: 19667203
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease.
    Schwerd T; Pandey S; Yang HT; Bagola K; Jameson E; Jung J; Lachmann RH; Shah N; Patel SY; Booth C; Runz H; Düker G; Bettels R; Rohrbach M; Kugathasan S; Chapel H; Keshav S; Elkadri A; Platt N; Muise AM; Koletzko S; Xavier RJ; Marquardt T; Powrie F; Wraith JE; Gyrd-Hansen M; Platt FM; Uhlig HH
    Gut; 2017 Jun; 66(6):1060-1073. PubMed ID: 26953272
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 14-3-3 and erlin proteins differentially interact with RIPK2 complexes.
    Steinle H; Ellwanger K; Mirza N; Briese S; Kienes I; Pfannstiel J; Kufer TA
    J Cell Sci; 2021 Jun; 134(12):. PubMed ID: 34152391
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RIPK2 NODs to XIAP and IBD.
    Topal Y; Gyrd-Hansen M
    Semin Cell Dev Biol; 2021 Jan; 109():144-150. PubMed ID: 32631784
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of Cell Death and Immunity by XIAP.
    Jost PJ; Vucic D
    Cold Spring Harb Perspect Biol; 2020 Aug; 12(8):. PubMed ID: 31843992
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.
    Bertrand MJ; Doiron K; Labbé K; Korneluk RG; Barker PA; Saleh M
    Immunity; 2009 Jun; 30(6):789-801. PubMed ID: 19464198
    [TBL] [Abstract][Full Text] [Related]  

  • 14. XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures.
    Ellwanger K; Briese S; Arnold C; Kienes I; Heim V; Nachbur U; Kufer TA
    Life Sci Alliance; 2019 Aug; 2(4):. PubMed ID: 31350258
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Postbiotics for NOD2 require nonhematopoietic RIPK2 to improve blood glucose and metabolic inflammation in mice.
    Cavallari JF; Barra NG; Foley KP; Lee A; Duggan BM; Henriksbo BD; Anhê FF; Ashkar AA; Schertzer JD
    Am J Physiol Endocrinol Metab; 2020 Apr; 318(4):E579-E585. PubMed ID: 32101030
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transcription of NOD1 and NOD2 and their interaction with CARD9 and RIPK2 in IFN signaling in a perciform fish, the Chinese perch,
    Peng XY; Wang KL; Li L; Li B; Wu XY; Zhang ZW; Li N; Liu LH; Nie P; Chen SN
    Front Immunol; 2024; 15():1374368. PubMed ID: 38715616
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The potent and selective RIPK2 inhibitor BI 706039 improves intestinal inflammation in the TRUC mouse model of inflammatory bowel disease.
    Ermann J; Matmusaev M; Haley EK; Braun C; Jost F; Mayer-Wrangowski S; Hsiao P; Ting N; Li L; Terenzio D; Chime J; Lukas S; Patnaude L; Panzenbeck M; Csordas D; Zheng J; Mierz D; Simpson T; King FJ; Klimowicz AP; Mbow ML; Fine JS; Miller CA; Fogal SE; Byrne FR
    Am J Physiol Gastrointest Liver Physiol; 2021 Nov; 321(5):G500-G512. PubMed ID: 34494462
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RIPK2 Dictates Insulin Responses to Tyrosine Kinase Inhibitors in Obese Male Mice.
    Duggan BM; Cavallari JF; Foley KP; Barra NG; Schertzer JD
    Endocrinology; 2020 Aug; 161(8):. PubMed ID: 32473019
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Receptor Interacting Ser/Thr-Protein Kinase 2 as a New Therapeutic Target.
    Rivoal M; Dubuquoy L; Millet R; Leleu-Chavain N
    J Med Chem; 2023 Nov; 66(21):14391-14410. PubMed ID: 37857324
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vivo inhibition of RIPK2 kinase alleviates inflammatory disease.
    Tigno-Aranjuez JT; Benderitter P; Rombouts F; Deroose F; Bai X; Mattioli B; Cominelli F; Pizarro TT; Hoflack J; Abbott DW
    J Biol Chem; 2014 Oct; 289(43):29651-64. PubMed ID: 25213858
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.