BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

297 related articles for article (PubMed ID: 30037754)

  • 1. Antiprotozoal and cysteine proteases inhibitory activity of dipeptidyl enoates.
    Royo S; Schirmeister T; Kaiser M; Jung S; Rodríguez S; Bautista JM; González FV
    Bioorg Med Chem; 2018 Sep; 26(16):4624-4634. PubMed ID: 30037754
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dipeptidyl Enoates As Potent Rhodesain Inhibitors That Display a Dual Mode of Action.
    Royo S; Rodríguez S; Schirmeister T; Kesselring J; Kaiser M; González FV
    ChemMedChem; 2015 Sep; 10(9):1484-7. PubMed ID: 26179752
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gold compounds as cysteine protease inhibitors: perspectives for pharmaceutical application as antiparasitic agents.
    Massai L; Messori L; Micale N; Schirmeister T; Maes L; Fregona D; Cinellu MA; Gabbiani C
    Biometals; 2017 Apr; 30(2):313-320. PubMed ID: 28283781
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors.
    Micale N; Ettari R; Schirmeister T; Evers A; Gelhaus C; Leippe M; Zappalà M; Grasso S
    Bioorg Med Chem; 2009 Sep; 17(18):6505-11. PubMed ID: 19709887
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of novel dipeptide-like rhodesain inhibitors containing the 3-bromoisoxazoline warhead in a constrained conformation.
    Ettari R; Pinto A; Previti S; Tamborini L; Angelo IC; La Pietra V; Marinelli L; Novellino E; Schirmeister T; Zappalà M; Grasso S; De Micheli C; Conti P
    Bioorg Med Chem; 2015 Nov; 23(21):7053-60. PubMed ID: 26432608
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dipeptidyl-alpha,beta-epoxyesters as potent irreversible inhibitors of the cysteine proteases cruzain and rhodesain.
    González FV; Izquierdo J; Rodríguez S; McKerrow JH; Hansell E
    Bioorg Med Chem Lett; 2007 Dec; 17(24):6697-700. PubMed ID: 17977725
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents.
    Yang PY; Wang M; Li L; Wu H; He CY; Yao SQ
    Chemistry; 2012 May; 18(21):6528-41. PubMed ID: 22488888
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of Novel Peptide-Based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs).
    Previti S; Ettari R; Cosconati S; Amendola G; Chouchene K; Wagner A; Hellmich UA; Ulrich K; Krauth-Siegel RL; Wich PR; Schmid I; Schirmeister T; Gut J; Rosenthal PJ; Grasso S; Zappalà M
    J Med Chem; 2017 Aug; 60(16):6911-6923. PubMed ID: 28763614
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Allicin and derivates are cysteine protease inhibitors with antiparasitic activity.
    Waag T; Gelhaus C; Rath J; Stich A; Leippe M; Schirmeister T
    Bioorg Med Chem Lett; 2010 Sep; 20(18):5541-3. PubMed ID: 20692829
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluation of dipeptide nitriles as inhibitors of rhodesain, a major cysteine protease of Trypanosoma brucei.
    Schirmeister T; Schmitz J; Jung S; Schmenger T; Krauth-Siegel RL; Gütschow M
    Bioorg Med Chem Lett; 2017 Jan; 27(1):45-50. PubMed ID: 27890381
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of quinoline derivatives as potential cysteine protease inhibitors.
    Andrade MM; Martins LC; Marques GV; Silva CA; Faria G; Caldas S; Dos Santos JS; Leclercq SY; Maltarollo VG; Ferreira RS; Oliveira RB
    Future Med Chem; 2020 Apr; 12(7):571-581. PubMed ID: 32116030
    [No Abstract]   [Full Text] [Related]  

  • 12. On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences.
    Machon U; Büchold C; Stempka M; Schirmeister T; Gelhaus C; Leippe M; Gut J; Rosenthal PJ; Kisker C; Leyh M; Schmuck C
    J Med Chem; 2009 Sep; 52(18):5662-72. PubMed ID: 19715342
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB.
    Mott BT; Ferreira RS; Simeonov A; Jadhav A; Ang KK; Leister W; Shen M; Silveira JT; Doyle PS; Arkin MR; McKerrow JH; Inglese J; Austin CP; Thomas CJ; Shoichet BK; Maloney DJ
    J Med Chem; 2010 Jan; 53(1):52-60. PubMed ID: 19908842
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of papain-family cathepsin L-like cysteine protease inhibitors containing a 1,4-benzodiazepine scaffold as antiprotozoal agents.
    Ettari R; Pinto A; Tamborini L; Angelo IC; Grasso S; Zappalà M; Capodicasa N; Yzeiraj L; Gruber E; Aminake MN; Pradel G; Schirmeister T; De Micheli C; Conti P
    ChemMedChem; 2014 Aug; 9(8):1817-25. PubMed ID: 24919925
    [TBL] [Abstract][Full Text] [Related]  

  • 15. α-ketoheterocycles as inhibitors of Leishmania mexicana cysteine protease CPB.
    Steert K; Berg M; Mottram JC; Westrop GD; Coombs GH; Cos P; Maes L; Joossens J; Van der Veken P; Haemers A; Augustyns K
    ChemMedChem; 2010 Oct; 5(10):1734-48. PubMed ID: 20799311
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, biological evaluation, hydration site thermodynamics, and chemical reactivity analysis of α-keto substituted peptidomimetics for the inhibition of Plasmodium falciparum.
    Weldon DJ; Shah F; Chittiboyina AG; Sheri A; Chada RR; Gut J; Rosenthal PJ; Shivakumar D; Sherman W; Desai P; Jung JC; Avery MA
    Bioorg Med Chem Lett; 2014 Mar; 24(5):1274-9. PubMed ID: 24507921
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1.
    Fonseca NC; da Cruz LF; da Silva Villela F; do Nascimento Pereira GA; de Siqueira-Neto JL; Kellar D; Suzuki BM; Ray D; de Souza TB; Alves RJ; Sales Júnior PA; Romanha AJ; Murta SM; McKerrow JH; Caffrey CR; de Oliveira RB; Ferreira RS
    Antimicrob Agents Chemother; 2015 May; 59(5):2666-77. PubMed ID: 25712353
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi.
    Greenbaum DC; Mackey Z; Hansell E; Doyle P; Gut J; Caffrey CR; Lehrman J; Rosenthal PJ; McKerrow JH; Chibale K
    J Med Chem; 2004 Jun; 47(12):3212-9. PubMed ID: 15163200
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antitrypanosomal and cysteine protease inhibitory activities of alkyldiamine cryptolepine derivatives.
    Lavrado J; Mackey Z; Hansell E; McKerrow JH; Paulo A; Moreira R
    Bioorg Med Chem Lett; 2012 Oct; 22(19):6256-60. PubMed ID: 22926067
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development of rhodesain inhibitors with a 3-bromoisoxazoline warhead.
    Ettari R; Tamborini L; Angelo IC; Grasso S; Schirmeister T; Lo Presti L; De Micheli C; Pinto A; Conti P
    ChemMedChem; 2013 Dec; 8(12):2070-6. PubMed ID: 24243827
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.