BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

375 related articles for article (PubMed ID: 30045877)

  • 1. Structural insights into oxidation of medium-chain fatty acids and flavanone by myxobacterial cytochrome P450 CYP267B1.
    Jóźwik IK; Litzenburger M; Khatri Y; Schifrin A; Girhard M; Urlacher V; Thunnissen AWH; Bernhardt R
    Biochem J; 2018 Sep; 475(17):2801-2817. PubMed ID: 30045877
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A natural heme-signature variant of CYP267A1 from Sorangium cellulosum So ce56 executes diverse ω-hydroxylation.
    Khatri Y; Hannemann F; Girhard M; Kappl R; Hutter M; Urlacher VB; Bernhardt R
    FEBS J; 2015 Jan; 282(1):74-88. PubMed ID: 25302415
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective oxidation of carotenoid-derived aroma compounds by CYP260B1 and CYP267B1 from Sorangium cellulosum So ce56.
    Litzenburger M; Bernhardt R
    Appl Microbiol Biotechnol; 2016 May; 100(10):4447-57. PubMed ID: 26767988
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural characterization of CYP260A1 from Sorangium cellulosum to investigate the 1α-hydroxylation of a mineralocorticoid.
    Khatri Y; Carius Y; Ringle M; Lancaster CR; Bernhardt R
    FEBS Lett; 2016 Dec; 590(24):4638-4648. PubMed ID: 27878817
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone.
    Khatri Y; Jóźwik IK; Ringle M; Ionescu IA; Litzenburger M; Hutter MC; Thunnissen AWH; Bernhardt R
    ACS Chem Biol; 2018 Apr; 13(4):1021-1028. PubMed ID: 29509407
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The CYPome of Sorangium cellulosum So ce56 and identification of CYP109D1 as a new fatty acid hydroxylase.
    Khatri Y; Hannemann F; Ewen KM; Pistorius D; Perlova O; Kagawa N; Brachmann AO; Müller R; Bernhardt R
    Chem Biol; 2010 Dec; 17(12):1295-305. PubMed ID: 21168765
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regioselective hydroxylation of norisoprenoids by CYP109D1 from Sorangium cellulosum So ce56.
    Khatri Y; Girhard M; Romankiewicz A; Ringle M; Hannemann F; Urlacher VB; Hutter MC; Bernhardt R
    Appl Microbiol Biotechnol; 2010 Sep; 88(2):485-95. PubMed ID: 20645086
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New Sesquiterpene Oxidations with CYP260A1 and CYP264B1 from Sorangium cellulosum So ce56.
    Schifrin A; Litzenburger M; Ringle M; Ly TT; Bernhardt R
    Chembiochem; 2015 Dec; 16(18):2624-32. PubMed ID: 26449371
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biochemical Characterization of CYP505D6, a Self-Sufficient Cytochrome P450 from the White-Rot Fungus Phanerochaete chrysosporium.
    Sakai K; Matsuzaki F; Wise L; Sakai Y; Jindou S; Ichinose H; Takaya N; Kato M; Wariishi H; Shimizu M
    Appl Environ Microbiol; 2018 Nov; 84(22):. PubMed ID: 30171007
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium.
    Jóźwik IK; Kiss FM; Gricman Ł; Abdulmughni A; Brill E; Zapp J; Pleiss J; Bernhardt R; Thunnissen AW
    FEBS J; 2016 Nov; 283(22):4128-4148. PubMed ID: 27686671
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insights into regioselective metabolism of mefenamic acid by cytochrome P450 BM3 mutants through crystallography, docking, molecular dynamics, and free energy calculations.
    Capoferri L; Leth R; ter Haar E; Mohanty AK; Grootenhuis PD; Vottero E; Commandeur JN; Vermeulen NP; Jørgensen FS; Olsen L; Geerke DP
    Proteins; 2016 Mar; 84(3):383-96. PubMed ID: 26757175
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel family members of CYP109 from Sorangium cellulosum So ce56 exhibit characteristic biochemical and biophysical properties.
    Khatri Y; Hannemann F; Girhard M; Kappl R; Même A; Ringle M; Janocha S; Leize-Wagner E; Urlacher VB; Bernhardt R
    Biotechnol Appl Biochem; 2013; 60(1):18-29. PubMed ID: 23586989
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium.
    Gustafsson MC; Roitel O; Marshall KR; Noble MA; Chapman SK; Pessegueiro A; Fulco AJ; Cheesman MR; von Wachenfeldt C; Munro AW
    Biochemistry; 2004 May; 43(18):5474-87. PubMed ID: 15122913
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus.
    Girvan HM; Poddar H; McLean KJ; Nelson DR; Hollywood KA; Levy CW; Leys D; Munro AW
    J Inorg Biochem; 2018 Nov; 188():18-28. PubMed ID: 30119014
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterisation of two self-sufficient CYP102 family monooxygenases from Ktedonobacter racemifer DSM44963 which have new fatty acid alcohol product profiles.
    Munday SD; Maddigan NK; Young RJ; Bell SG
    Biochim Biophys Acta; 2016 Jun; 1860(6):1149-62. PubMed ID: 26825771
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytochrome P450 2A6 and other human P450 enzymes in the oxidation of flavone and flavanone.
    Kakimoto K; Murayama N; Takenaka S; Nagayoshi H; Lim YR; Kim V; Kim D; Yamazaki H; Komori M; Guengerich FP; Shimada T
    Xenobiotica; 2019 Feb; 49(2):131-142. PubMed ID: 29310511
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CYP267A1 and CYP267B1 from Sorangium cellulosum So ce56 are Highly Versatile Drug Metabolizers.
    Kern F; Khatri Y; Litzenburger M; Bernhardt R
    Drug Metab Dispos; 2016 Apr; 44(4):495-504. PubMed ID: 26842594
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regioselective hydroxylation of C(12)-C(15) fatty acids with fluorinated substituents by cytochrome P450 BM3.
    Chiang CH; Ramu R; Tu YJ; Yang CL; Ng KY; Luo WI; Chen CH; Lu YY; Liu CL; Yu SS
    Chemistry; 2013 Oct; 19(41):13680-91. PubMed ID: 24092541
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
    Cryle MJ; Schlichting I
    Proc Natl Acad Sci U S A; 2008 Oct; 105(41):15696-701. PubMed ID: 18838690
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oxidative biotransformation of fatty acids by cytochromes P450: predicted key structural elements orchestrating substrate specificity, regioselectivity and catalytic efficiency.
    Hlavica P; Lehnerer M
    Curr Drug Metab; 2010 Jan; 11(1):85-104. PubMed ID: 20302567
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.