643 related articles for article (PubMed ID: 30047829)
1. Probing the "fingers" domain binding pocket of Hepatitis C virus NS5B RdRp and D559G resistance mutation via molecular docking, molecular dynamics simulation and binding free energy calculations.
Manjula S; Sivanandam M; Kumaradhas P
J Biomol Struct Dyn; 2019 Jun; 37(9):2440-2456. PubMed ID: 30047829
[TBL] [Abstract][Full Text] [Related]
2. Evaluating the suitability of RNA intervention mechanism exerted by some flavonoid molecules against dengue virus MTase RNA capping site: a molecular docking, molecular dynamics simulation, and binding free energy study.
Manjula S; Kumaradhas P
J Biomol Struct Dyn; 2020 Aug; 38(12):3533-3543. PubMed ID: 31514688
[TBL] [Abstract][Full Text] [Related]
3. Molecular modeling and residue interaction network studies on the mechanism of binding and resistance of the HCV NS5B polymerase mutants to VX-222 and ANA598.
Xue W; Jiao P; Liu H; Yao X
Antiviral Res; 2014 Apr; 104():40-51. PubMed ID: 24462692
[TBL] [Abstract][Full Text] [Related]
4. Computational study on the drug resistance mechanism of HCV NS5B RNA-dependent RNA polymerase mutants V494I, V494A, M426A, and M423T to Filibuvir.
Wang H; Guo C; Chen BZ; Ji M
Antiviral Res; 2015 Jan; 113():79-92. PubMed ID: 25449363
[TBL] [Abstract][Full Text] [Related]
5. Understanding the drug resistance mechanism of hepatitis C virus NS5B to PF-00868554 due to mutations of the 423 site: a computational study.
Jiao P; Xue W; Shen Y; Jin N; Liu H
Mol Biosyst; 2014 Apr; 10(4):767-77. PubMed ID: 24452008
[TBL] [Abstract][Full Text] [Related]
6. Interference of HCV replication by cell penetrable human monoclonal scFv specific to NS5B polymerase.
Thueng-in K; Thanongsaksrikul J; Jittavisutthikul S; Seesuay W; Chulanetra M; Sakolvaree Y; Srimanote P; Chaicumpa W
MAbs; 2014; 6(5):1327-39. PubMed ID: 25517317
[TBL] [Abstract][Full Text] [Related]
7. Discovery of novel natural flavonoids as potent antiviral candidates against hepatitis C virus NS5B polymerase.
Akher FB; Farrokhzadeh A; Ramharack P; Shunmugam L; Van Heerden FR; Soliman MES
Med Hypotheses; 2019 Nov; 132():109359. PubMed ID: 31466018
[TBL] [Abstract][Full Text] [Related]
8. Combined 3D-QSAR, molecular docking, molecular dynamics simulation, and binding free energy calculation studies on the 5-hydroxy-2H-pyridazin-3-one derivatives as HCV NS5B polymerase inhibitors.
Yu H; Fang Y; Lu X; Liu Y; Zhang H
Chem Biol Drug Des; 2014 Jan; 83(1):89-105. PubMed ID: 23941500
[TBL] [Abstract][Full Text] [Related]
9. NMR reveals the intrinsically disordered domain 2 of NS5A protein as an allosteric regulator of the hepatitis C virus RNA polymerase NS5B.
Bessa LM; Launay H; Dujardin M; Cantrelle FX; Lippens G; Landrieu I; Schneider R; Hanoulle X
J Biol Chem; 2017 Nov; 292(44):18024-18043. PubMed ID: 28912275
[TBL] [Abstract][Full Text] [Related]
10. Phosphorylation at the N-terminal finger subdomain of a viral RNA-dependent RNA polymerase.
Hernández S; Figueroa D; Correa S; Díaz A; Aguayo D; Villanueva RA
Biochem Biophys Res Commun; 2015 Oct; 466(1):21-7. PubMed ID: 26301630
[TBL] [Abstract][Full Text] [Related]
11. Functional characterization of fingers subdomain-specific monoclonal antibodies inhibiting the hepatitis C virus RNA-dependent RNA polymerase.
Nikonov A; Juronen E; Ustav M
J Biol Chem; 2008 Aug; 283(35):24089-102. PubMed ID: 18574240
[TBL] [Abstract][Full Text] [Related]
12. Thumb inhibitor binding eliminates functionally important dynamics in the hepatitis C virus RNA polymerase.
Davis BC; Thorpe IF
Proteins; 2013 Jan; 81(1):40-52. PubMed ID: 22855387
[TBL] [Abstract][Full Text] [Related]
13. Phosphorylation of hepatitis C virus RNA polymerases ser29 and ser42 by protein kinase C-related kinase 2 regulates viral RNA replication.
Han SH; Kim SJ; Kim EJ; Kim TE; Moon JS; Kim GW; Lee SH; Cho K; Yoo JS; Son WS; Rhee JK; Han SH; Oh JW
J Virol; 2014 Oct; 88(19):11240-52. PubMed ID: 25031343
[TBL] [Abstract][Full Text] [Related]
14. Allosteric mechanism of cyclopropylindolobenzazepine inhibitors for HCV NS5B RdRp via dynamic correlation network analysis.
Rahman MU; Liu H; Wadood A; Chen HF
Mol Biosyst; 2016 Oct; 12(11):3280-3293. PubMed ID: 27528077
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of RNA binding to hepatitis C virus RNA-dependent RNA polymerase: a new mechanism for antiviral intervention.
Ahmed-Belkacem A; Guichou JF; Brillet R; Ahnou N; Hernandez E; Pallier C; Pawlotsky JM
Nucleic Acids Res; 2014 Aug; 42(14):9399-409. PubMed ID: 25053847
[TBL] [Abstract][Full Text] [Related]
16. Repositioning of RdRp Inhibitors Against HCV NS5B Polymerase Utilizing Structure-Based Molecular Docking.
Tarannum H; Nandi S
Comb Chem High Throughput Screen; 2022; 25(4):702-719. PubMed ID: 33475069
[TBL] [Abstract][Full Text] [Related]
17. Ligand-induced changes in hepatitis C virus NS5B polymerase structure.
Rigat K; Wang Y; Hudyma TW; Ding M; Zheng X; Gentles RG; Beno BR; Gao M; Roberts SB
Antiviral Res; 2010 Nov; 88(2):197-206. PubMed ID: 20813137
[TBL] [Abstract][Full Text] [Related]
18. Computational study on the drug resistance mechanism against HCV NS3/4A protease inhibitors vaniprevir and MK-5172 by the combination use of molecular dynamics simulation, residue interaction network, and substrate envelope analysis.
Xue W; Ban Y; Liu H; Yao X
J Chem Inf Model; 2014 Feb; 54(2):621-33. PubMed ID: 23745769
[TBL] [Abstract][Full Text] [Related]
19. Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors.
Biswal BK; Cherney MM; Wang M; Chan L; Yannopoulos CG; Bilimoria D; Nicolas O; Bedard J; James MN
J Biol Chem; 2005 May; 280(18):18202-10. PubMed ID: 15746101
[TBL] [Abstract][Full Text] [Related]
20. Discovery of novel Hepatitis C virus inhibitor targeting multiple allosteric sites of NS5B polymerase.
Khalid H; Landry KB; Ijaz B; Ashfaq UA; Ahmed M; Kanwal A; Froeyen M; Mirza MU
Infect Genet Evol; 2020 Oct; 84():104371. PubMed ID: 32485331
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
