348 related articles for article (PubMed ID: 30050002)
1. VKORC1L1, An Enzyme Mediating the Effect of Vitamin K in Liver and Extrahepatic Tissues.
Lacombe J; Ferron M
Nutrients; 2018 Jul; 10(8):. PubMed ID: 30050002
[TBL] [Abstract][Full Text] [Related]
2. VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo.
Lacombe J; Rishavy MA; Berkner KL; Ferron M
JCI Insight; 2018 Jan; 3(1):. PubMed ID: 29321368
[TBL] [Abstract][Full Text] [Related]
3. VKORC1L1, an enzyme rescuing the vitamin K 2,3-epoxide reductase activity in some extrahepatic tissues during anticoagulation therapy.
Hammed A; Matagrin B; Spohn G; Prouillac C; Benoit E; Lattard V
J Biol Chem; 2013 Oct; 288(40):28733-42. PubMed ID: 23928358
[TBL] [Abstract][Full Text] [Related]
4. VKORC1 and VKORC1L1 have distinctly different oral anticoagulant dose-response characteristics and binding sites.
Czogalla KJ; Liphardt K; Höning K; Hornung V; Biswas A; Watzka M; Oldenburg J
Blood Adv; 2018 Mar; 2(6):691-702. PubMed ID: 29581108
[TBL] [Abstract][Full Text] [Related]
5. Two enzymes catalyze vitamin K 2,3-epoxide reductase activity in mouse: VKORC1 is highly expressed in exocrine tissues while VKORC1L1 is highly expressed in brain.
Caspers M; Czogalla KJ; Liphardt K; Müller J; Westhofen P; Watzka M; Oldenburg J
Thromb Res; 2015 May; 135(5):977-83. PubMed ID: 25747820
[TBL] [Abstract][Full Text] [Related]
6. Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase.
Rishavy MA; Hallgren KW; Wilson L; Singh S; Runge KW; Berkner KL
Blood; 2018 Jun; 131(25):2826-2835. PubMed ID: 29592891
[TBL] [Abstract][Full Text] [Related]
7. Conserved loop cysteines of vitamin K epoxide reductase complex subunit 1-like 1 (VKORC1L1) are involved in its active site regeneration.
Tie JK; Jin DY; Stafford DW
J Biol Chem; 2014 Mar; 289(13):9396-407. PubMed ID: 24532791
[TBL] [Abstract][Full Text] [Related]
8. The vitamin K oxidoreductase is a multimer that efficiently reduces vitamin K epoxide to hydroquinone to allow vitamin K-dependent protein carboxylation.
Rishavy MA; Hallgren KW; Wilson LA; Usubalieva A; Runge KW; Berkner KL
J Biol Chem; 2013 Nov; 288(44):31556-66. PubMed ID: 23918929
[TBL] [Abstract][Full Text] [Related]
9. Avian interspecific differences in VKOR activity and inhibition: Insights from amino acid sequence and mRNA expression ratio of VKORC1 and VKORC1L1.
Nakayama SMM; Morita A; Ikenaka Y; Kawai YK; Watanabe KP; Ishii C; Mizukawa H; Yohannes YB; Saito K; Watanabe Y; Ito M; Ohsawa N; Ishizuka M
Comp Biochem Physiol C Toxicol Pharmacol; 2020 Feb; 228():108635. PubMed ID: 31639498
[TBL] [Abstract][Full Text] [Related]
10. Stabilization of warfarin-binding pocket of VKORC1 and VKORL1 by a peripheral region determines their different sensitivity to warfarin inhibition.
Shen G; Li S; Cui W; Liu S; Liu Q; Yang Y; Gross M; Li W
J Thromb Haemost; 2018 Jun; 16(6):1164-1175. PubMed ID: 29665197
[TBL] [Abstract][Full Text] [Related]
11. Structural Insights into Phylloquinone (Vitamin K1), Menaquinone (MK4, MK7), and Menadione (Vitamin K3) Binding to VKORC1.
Chatron N; Hammed A; Benoît E; Lattard V
Nutrients; 2019 Jan; 11(1):. PubMed ID: 30609653
[TBL] [Abstract][Full Text] [Related]
12. Site-directed mutagenesis of coumarin-type anticoagulant-sensitive VKORC1: evidence that highly conserved amino acids define structural requirements for enzymatic activity and inhibition by warfarin.
Rost S; Fregin A; Hünerberg M; Bevans CG; Müller CR; Oldenburg J
Thromb Haemost; 2005 Oct; 94(4):780-6. PubMed ID: 16270630
[TBL] [Abstract][Full Text] [Related]
13. Regulation of VKORC1L1 is critical for p53-mediated tumor suppression through vitamin K metabolism.
Yang X; Wang Z; Zandkarimi F; Liu Y; Duan S; Li Z; Kon N; Zhang Z; Jiang X; Stockwell BR; Gu W
Cell Metab; 2023 Aug; 35(8):1474-1490.e8. PubMed ID: 37467745
[TBL] [Abstract][Full Text] [Related]
14. Mechanism of VKORC1 and VKORC1L1 signaling in the effects of sodium dehydroacetate on coagulation factors in rat hepatocytes.
Zhou Z; Chen B; Zhang M; Chen X; Zhang Y
Toxicol In Vitro; 2023 Mar; 87():105518. PubMed ID: 36403723
[TBL] [Abstract][Full Text] [Related]
15. VKORC1: a warfarin-sensitive enzyme in vitamin K metabolism and biosynthesis of vitamin K-dependent blood coagulation factors.
Wallin R; Wajih N; Hutson SM
Vitam Horm; 2008; 78():227-46. PubMed ID: 18374197
[TBL] [Abstract][Full Text] [Related]
16. Polymorphisms of vitamin K-related genes (EPHX1 and VKORC1L1) and stable warfarin doses.
Chung JE; Lee KE; Chang BC; Gwak HS
Gene; 2018 Jan; 641():68-73. PubMed ID: 29054760
[TBL] [Abstract][Full Text] [Related]
17. Disulfide-dependent protein folding is linked to operation of the vitamin K cycle in the endoplasmic reticulum. A protein disulfide isomerase-VKORC1 redox enzyme complex appears to be responsible for vitamin K1 2,3-epoxide reduction.
Wajih N; Hutson SM; Wallin R
J Biol Chem; 2007 Jan; 282(4):2626-35. PubMed ID: 17124179
[TBL] [Abstract][Full Text] [Related]
18. Structural Investigation of the Vitamin K Epoxide Reductase (VKORC1) Binding Site with Vitamin K.
Chatron N; Abi Khalil R; Benoit E; Lattard V
Biochemistry; 2020 Apr; 59(13):1351-1360. PubMed ID: 32182040
[TBL] [Abstract][Full Text] [Related]
19. Engineering of a recombinant vitamin K-dependent gamma-carboxylation system with enhanced gamma-carboxyglutamic acid forming capacity: evidence for a functional CXXC redox center in the system.
Wajih N; Sane DC; Hutson SM; Wallin R
J Biol Chem; 2005 Mar; 280(11):10540-7. PubMed ID: 15640149
[TBL] [Abstract][Full Text] [Related]
20. New Insights on Vitamin K Metabolism in Senegalese sole (
Beato S; Marques C; Laizé V; Gavaia PJ; Fernández I
Int J Mol Sci; 2020 May; 21(10):. PubMed ID: 32429051
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
