BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

406 related articles for article (PubMed ID: 30051592)

  • 1. Computational Approaches to Develop Isoquinoline Based Antibiotics through DNA Gyrase Inhibition Mechanisms Unveiled through Antibacterial Evaluation and Molecular Docking.
    Alagumuthu M; Muralidharan VP; Andrew M; Ahmed MH; Iyer SK; Arumugam S
    Mol Inform; 2018 Dec; 37(12):e1800048. PubMed ID: 30051592
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular docking, discovery, synthesis, and pharmacological properties of new 6-substituted-2-(3-phenoxyphenyl)-4-phenyl quinoline derivatives; an approach to developing potent DNA gyrase inhibitors/antibacterial agents.
    Alagumuthu M; Arumugam S
    Bioorg Med Chem; 2017 Feb; 25(4):1448-1455. PubMed ID: 28094220
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Drug efficacy of novel 3-O-methoxy-4-halo disubstituted 5,7-dimethoxy chromans; evaluated via DNA gyrase inhibition, bacterial cell wall lesion and antibacterial prospective.
    Ponnusamy T; Alagumuthu M; Thamaraiselvi S
    Bioorg Med Chem; 2018 Jul; 26(12):3438-3452. PubMed ID: 29803359
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study.
    Ibrahim TS; Almalki AJ; Moustafa AH; Allam RM; Abuo-Rahma GEA; El Subbagh HI; Mohamed MFA
    Bioorg Chem; 2021 Jun; 111():104885. PubMed ID: 33838559
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antibacterial Evaluation and Virtual Screening of New Thiazolyl-Triazole Schiff Bases as Potential DNA-Gyrase Inhibitors.
    Nastasă C; Vodnar DC; Ionuţ I; Stana A; Benedec D; Tamaian R; Oniga O; Tiperciuc B
    Int J Mol Sci; 2018 Jan; 19(1):. PubMed ID: 29324679
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of novel multi-substituted benzo-indole pyrazole schiff base derivatives with antibacterial activity targeting DNA gyrase.
    Liu H; Chu ZW; Xia DG; Cao HQ; Lv XH
    Bioorg Chem; 2020 Jun; 99():103807. PubMed ID: 32272364
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, antimicrobial activity and molecular modeling study of substituted 5-aryl-pyrimido[5,4-c]quinoline-2,4-diones.
    Ismail MA; Al-Shihry S; Arafa RK; El-Ayaan U
    J Enzyme Inhib Med Chem; 2013 Jun; 28(3):530-8. PubMed ID: 22397395
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, antimicrobial evaluation, DNA gyrase inhibition, and in silico pharmacokinetic studies of novel quinoline derivatives.
    El-Shershaby MH; El-Gamal KM; Bayoumi AH; El-Adl K; Ahmed HEA; Abulkhair HS
    Arch Pharm (Weinheim); 2021 Feb; 354(2):e2000277. PubMed ID: 33078877
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, antimicrobial activity and molecular modeling study of 3-(5-amino-(2H)-1,2,4-triazol-3-yl]-naphthyridinones as potential DNA-gyrase inhibitors.
    Mohamed NG; Sheha MM; Hassan HY; Abdel-Hafez LJM; Omar FA
    Bioorg Chem; 2018 Dec; 81():599-611. PubMed ID: 30248511
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, green one-pot synthesis and molecular docking study of novel N,N-bis(cyanoacetyl)hydrazines and bis-coumarins as effective inhibitors of DNA gyrase and topoisomerase IV.
    Metwally NH; Abdallah SO; Mohsen MMA
    Bioorg Chem; 2020 Apr; 97():103672. PubMed ID: 32145481
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity.
    Hassan AS; Askar AA; Naglah AM; Almehizia AA; Ragab A
    Molecules; 2020 Jun; 25(11):. PubMed ID: 32498469
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, in vitro antimicrobial evaluation and molecular docking studies of indol-2-one tagged with morpholinosulfonyl moiety as DNA gyrase inhibitors.
    Salem MA; Ragab A; El-Khalafawy A; Makhlouf AH; Askar AA; Ammar YA
    Bioorg Chem; 2020 Mar; 96():103619. PubMed ID: 32036161
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dual inhibition of Staphylococcus aureus DNA gyrase and topoisomerase IV activity by phenylalanine-derived (Z)-5-arylmethylidene rhodanines.
    Werner MM; Patel BA; Talele TT; Ashby CR; Li Z; Zauhar RJ
    Bioorg Med Chem; 2015 Sep; 23(18):6125-37. PubMed ID: 26320664
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure based design and synthesis of 3-(7-nitro-3-oxo-3,4-dihydroquinoxalin-2-yl)propanehydrazide derivatives as novel bacterial DNA-gyrase inhibitors: In-vitro, In-vivo, In-silico and SAR studies.
    Saleh MA; Elmaaty AA; El Saeed HS; Saleh MM; Salah M; Ezz Eldin RR
    Bioorg Chem; 2022 Dec; 129():106186. PubMed ID: 36215786
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and molecular docking of new N4-piperazinyl ciprofloxacin hybrids as antimicrobial DNA gyrase inhibitors.
    Mohammed HHH; Ali DME; Badr M; Habib AGK; Mahmoud AM; Farhan SM; Gany SSHAE; Mohamad SA; Hayallah AM; Abbas SH; Abuo-Rahma GEA
    Mol Divers; 2023 Aug; 27(4):1751-1765. PubMed ID: 36152132
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, Docking Studies, and In Vitro Evaluation of Some Novel Thienopyridines and Fused Thienopyridine-Quinolines as Antibacterial Agents and DNA Gyrase Inhibitors.
    Mohi El-Deen EM; Abd El-Meguid EA; Hasabelnaby S; Karam EA; Nossier ES
    Molecules; 2019 Oct; 24(20):. PubMed ID: 31658631
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development and radiosterilization of new hydrazono-quinoline hybrids as DNA gyrase and topoisomerase IV inhibitors: Antimicrobial and hemolytic activities against uropathogenic isolates with molecular docking study.
    Ammar YA; Micky JA; Aboul-Magd DS; Abd El-Hafez SMA; Hessein SA; Ali AM; Ragab A
    Chem Biol Drug Des; 2023 Feb; 101(2):245-270. PubMed ID: 36305722
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and In Silico Molecular Docking Studies on Substituted Piperic Acid Derivatives as Inhibitors of Bacterial DNA Gyrase.
    Chopra B; Dhingra AK; Prasad DN; Bhardwaj S; Dubey S
    Curr Comput Aided Drug Des; 2020; 16(3):281-294. PubMed ID: 31288729
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, and antibacterial activity of novel 4,5-dihydro-1H-pyrazole derivatives as DNA gyrase inhibitors.
    Liu JJ; Sun J; Fang YB; Yang YA; Jiao RH; Zhu HL
    Org Biomol Chem; 2014 Feb; 12(6):998-1008. PubMed ID: 24382549
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV.
    Hofny HA; Mohamed MFA; Gomaa HAM; Abdel-Aziz SA; Youssif BGM; El-Koussi NA; Aboraia AS
    Bioorg Chem; 2021 Jul; 112():104920. PubMed ID: 33910078
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.