These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 30055887)

  • 1. Design and synthesis of novel thiadiazole-thiazolone hybrids as potential inhibitors of the human mitotic kinesin Eg5.
    Khathi SP; Chandrasekaran B; Karunanidhi S; Tham CL; Kozielski F; Sayyad N; Karpoormath R
    Bioorg Med Chem Lett; 2018 Sep; 28(17):2930-2938. PubMed ID: 30055887
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors.
    Talapatra SK; Tham CL; Guglielmi P; Cirilli R; Chandrasekaran B; Karpoormath R; Carradori S; Kozielski F
    Eur J Med Chem; 2018 Aug; 156():641-651. PubMed ID: 30031975
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New chemical tools for investigating human mitotic kinesin Eg5.
    Klein E; DeBonis S; Thiede B; Skoufias DA; Kozielski F; Lebeau L
    Bioorg Med Chem; 2007 Oct; 15(19):6474-88. PubMed ID: 17587586
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel photochromic inhibitor for mitotic kinesin Eg5 which forms multiple isomerization states.
    Alrazi IM; Sadakane K; Maruta S
    J Biochem; 2021 Oct; 170(2):229-237. PubMed ID: 33752234
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-activity relationship of pyrazolo pyrimidine derivatives as inhibitors of mitotic kinesin Eg5 and anticancer agents.
    Muthuraja P; Veeramani V; Prakash S; Himesh M; Venkatasubramanian U; Manisankar P
    Bioorg Chem; 2019 Mar; 84():493-504. PubMed ID: 30594885
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Highly efficient photocontrol of mitotic kinesin Eg5 ATPase activity using a novel photochromic compound composed of two azobenzene derivatives.
    Sadakane K; Alrazi IMD; Maruta S
    J Biochem; 2018 Oct; 164(4):295-301. PubMed ID: 29860530
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthetic studies on mitotic kinesin Eg5 inhibitors: synthesis and structure-activity relationships of novel 2,4,5-substituted-1,3,4-thiadiazoline derivatives.
    Yamamoto J; Amishiro N; Kato K; Ohta Y; Ino Y; Araki M; Tsujita T; Okamoto S; Takahashi T; Kusaka H; Akinaga S; Yamashita Y; Nakai R; Murakata C
    Bioorg Med Chem Lett; 2014 Aug; 24(16):3961-3. PubMed ID: 25001485
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design of new phenothiazine-thiadiazole hybrids via molecular hybridization approach for the development of potent antitubercular agents.
    Ramprasad J; Nayak N; Dalimba U
    Eur J Med Chem; 2015 Dec; 106():75-84. PubMed ID: 26520841
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, anticancer screening, docking studies and in silico ADME prediction of some β-carboline derivatives.
    Abdelsalam MA; AboulWafa OM; M Badawey EA; El-Shoukrofy MS; El-Miligy MM; Gouda N; Elaasser MM
    Future Med Chem; 2018 May; 10(10):1159-1175. PubMed ID: 29787297
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Kinesin Eg5 Targeting Inhibitors as a New Strategy for Gastric Adenocarcinoma Treatment.
    Marconi GD; Carradori S; Ricci A; Guglielmi P; Cataldi A; Zara S
    Molecules; 2019 Oct; 24(21):. PubMed ID: 31683688
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Morelloflavone as a novel inhibitor of mitotic kinesin Eg5.
    Ogunwa TH; Taii K; Sadakane K; Kawata Y; Maruta S; Miyanishi T
    J Biochem; 2019 Aug; 166(2):129-137. PubMed ID: 30785183
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Drug-1,3,4-Thiadiazole Conjugates as Novel Mixed-Type Inhibitors of Acetylcholinesterase: Synthesis, Molecular Docking, Pharmacokinetics, and ADMET Evaluation.
    Ujan R; Saeed A; Channar PA; Larik FA; Abbas Q; Alajmi MF; El-Seedi HR; Rind MA; Hassan M; Raza H; Seo SY
    Molecules; 2019 Feb; 24(5):. PubMed ID: 30823444
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds.
    Romagnoli R; Baraldi PG; Prencipe F; Balzarini J; Liekens S; Estévez F
    Eur J Med Chem; 2015 Aug; 101():205-17. PubMed ID: 26141911
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Photo-control of the mitotic kinesin Eg5 using a novel photochromic inhibitor composed of a spiropyran derivative.
    Sadakane K; Takaichi M; Maruta S
    J Biochem; 2018 Sep; 164(3):239-246. PubMed ID: 29718428
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of some new pyrazole-based 1,3-thiazoles and 1,3,4-thiadiazoles as anticancer agents.
    Dawood KM; Eldebss TM; El-Zahabi HS; Yousef MH; Metz P
    Eur J Med Chem; 2013; 70():740-9. PubMed ID: 24231309
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interaction of the mitotic inhibitor monastrol with human kinesin Eg5.
    DeBonis S; Simorre JP; Crevel I; Lebeau L; Skoufias DA; Blangy A; Ebel C; Gans P; Cross R; Hackney DD; Wade RH; Kozielski F
    Biochemistry; 2003 Jan; 42(2):338-49. PubMed ID: 12525161
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-activity relationship and multidrug resistance study of new S-trityl-L-cysteine derivatives as inhibitors of Eg5.
    Kaan HY; Weiss J; Menger D; Ulaganathan V; Tkocz K; Laggner C; Popowycz F; Joseph B; Kozielski F
    J Med Chem; 2011 Mar; 54(6):1576-86. PubMed ID: 21344920
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of the protein binding region of S-trityl-L-cysteine, a new potent inhibitor of the mitotic kinesin Eg5.
    Brier S; Lemaire D; Debonis S; Forest E; Kozielski F
    Biochemistry; 2004 Oct; 43(41):13072-82. PubMed ID: 15476401
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The marine natural product adociasulfate-2 as a tool to identify the MT-binding region of kinesins.
    Brier S; Carletti E; DeBonis S; Hewat E; Lemaire D; Kozielski F
    Biochemistry; 2006 Dec; 45(51):15644-53. PubMed ID: 17176086
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Corrigendum to "Design and synthesis of novel thiadiazole-thiazolone hybrids as potential inhibitors of the human mitotic kinesin Eg5 [Bioorg Med Chem Lett 28 (17) (2018) 2930-2938]".
    Khathi SP; Chandrasekaran B; Karunanidhi S; Tham CL; Kozielski F; Sayyad N; Karpoormath R
    Bioorg Med Chem Lett; 2018 Nov; 28(21):3489. PubMed ID: 30279037
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 7.