BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 30066088)

  • 21. Analysis of acute leukemias with MLL/ENL fusion transcripts: identification of two novel breakpoints in ENL.
    Fu JF; Liang DC; Shih LY
    Am J Clin Pathol; 2007 Jan; 127(1):24-30. PubMed ID: 17145626
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth.
    Wu F; Nie S; Yao Y; Huo T; Li X; Wu X; Zhao J; Lin YL; Zhang Y; Mo Q; Song Y
    Theranostics; 2021; 11(17):8172-8184. PubMed ID: 34373735
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The interaction of ENL with PAF1 mitigates polycomb silencing and facilitates murine leukemogenesis.
    Hetzner K; Garcia-Cuellar MP; Büttner C; Slany RK
    Blood; 2018 Feb; 131(6):662-673. PubMed ID: 29217648
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
    Song L; Yao X; Li H; Peng B; Boka AP; Liu Y; Chen G; Liu Z; Mathias KM; Xia L; Li Q; Mir M; Li Y; Li H; Wan L
    Mol Cell; 2022 Nov; 82(21):4080-4098.e12. PubMed ID: 36272410
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia.
    Garnar-Wortzel L; Bishop TR; Kitamura S; Milosevich N; Asiaban JN; Zhang X; Zheng Q; Chen E; Ramos AR; Ackerman CJ; Hampton EN; Chatterjee AK; Young TS; Hull MV; Sharpless KB; Cravatt BF; Wolan DW; Erb MA
    ACS Cent Sci; 2021 May; 7(5):815-830. PubMed ID: 34079898
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.
    Nie Z; Yan Z; Chen EH; Sechi S; Ling C; Zhou S; Xue Y; Yang D; Murray D; Kanakubo E; Cleary ML; Wang W
    Mol Cell Biol; 2003 Apr; 23(8):2942-52. PubMed ID: 12665591
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Condensate-promoting ENL mutation drives tumorigenesis in vivo through dynamic regulation of histone modifications and gene expression.
    Liu Y; Li Q; Song L; Gong C; Tang S; Budinich KA; Vanderbeck A; Mathias KM; Wertheim GB; Nguyen SC; Outen R; Joyce EF; Maillard I; Wan L
    Cancer Discov; 2024 Apr; ():. PubMed ID: 38655899
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The efficiency of murine MLL-ENL-driven leukemia initiation changes with age and peaks during neonatal development.
    Okeyo-Owuor T; Li Y; Patel RM; Yang W; Casey EB; Cluster AS; Porter SN; Bryder D; Magee JA
    Blood Adv; 2019 Aug; 3(15):2388-2399. PubMed ID: 31405949
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable
    Michino M; Khan TA; Miller MW; Fukase Y; Vendome J; Adura C; Glickman JF; Liu Y; Wan L; Allis CD; Stamford AW; Meinke PT; Renzetti LM; Kargman S; Liverton NJ; Huggins DJ
    ACS Med Chem Lett; 2024 Apr; 15(4):524-532. PubMed ID: 38628784
    [TBL] [Abstract][Full Text] [Related]  

  • 30. MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours.
    Perlman EJ; Gadd S; Arold ST; Radhakrishnan A; Gerhard DS; Jennings L; Huff V; Guidry Auvil JM; Davidsen TM; Dome JS; Meerzaman D; Hsu CH; Nguyen C; Anderson J; Ma Y; Mungall AJ; Moore RA; Marra MA; Mullighan CG; Ma J; Wheeler DA; Hampton OA; Gastier-Foster JM; Ross N; Smith MA
    Nat Commun; 2015 Dec; 6():10013. PubMed ID: 26635203
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Tet1 is not required for myeloid leukemogenesis by MLL-ENL in novel mouse models.
    Ono R; Masuya M; Inoue N; Shinmei M; Ishii S; Maegawa Y; Maharjan BD; Katayama N; Nosaka T
    PLoS One; 2021; 16(3):e0248425. PubMed ID: 33705482
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC.
    Guo S; Jia T; Xu X; Yang F; Xiao S; Hou Z; Xu H; Ma S; Liu X; Luo C; Jiang H; Chen H; Chen S
    Eur J Med Chem; 2023 Feb; 248():115093. PubMed ID: 36645983
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Disordered epigenetic regulation in MLL-related leukemia.
    Zhang Y; Chen A; Yan XM; Huang G
    Int J Hematol; 2012 Oct; 96(4):428-37. PubMed ID: 23054645
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The AML1 gene: a transcription factor involved in the pathogenesis of myeloid and lymphoid leukemias.
    Lo Coco F; Pisegna S; Diverio D
    Haematologica; 1997; 82(3):364-70. PubMed ID: 9234595
    [TBL] [Abstract][Full Text] [Related]  

  • 35. ENL, the gene fused with HRX in t(11;19) leukemias, encodes a nuclear protein with transcriptional activation potential in lymphoid and myeloid cells.
    Rubnitz JE; Morrissey J; Savage PA; Cleary ML
    Blood; 1994 Sep; 84(6):1747-52. PubMed ID: 8080983
    [TBL] [Abstract][Full Text] [Related]  

  • 36. CTCF boundary remodels chromatin domain and drives aberrant
    Luo H; Wang F; Zha J; Li H; Yan B; Du Q; Yang F; Sobh A; Vulpe C; Drusbosky L; Cogle C; Chepelev I; Xu B; Nimer SD; Licht J; Qiu Y; Chen B; Xu M; Huang S
    Blood; 2018 Aug; 132(8):837-848. PubMed ID: 29760161
    [No Abstract]   [Full Text] [Related]  

  • 37. Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells.
    Kawagoe H; Humphries RK; Blair A; Sutherland HJ; Hogge DE
    Leukemia; 1999 May; 13(5):687-98. PubMed ID: 10374871
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A New Complex Karyotype Involving a KMT2A-r Variant Three-Way Translocation in a Rare Clinical Presentation of a Pediatric Patient with Acute Myeloid Leukemia.
    Capela de Matos RR; Ney Garcia DR; Othman MAK; Moura Ferreira G; Melo JB; Carreira IM; Meyer C; Marschalek R; Costa ES; Land MGP; Liehr T; Ribeiro RC; Silva MLM
    Cytogenet Genome Res; 2019; 157(4):213-219. PubMed ID: 30974445
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Recognition of histone acetylation by the GAS41 YEATS domain promotes H2A.Z deposition in non-small cell lung cancer.
    Hsu CC; Shi J; Yuan C; Zhao D; Jiang S; Lyu J; Wang X; Li H; Wen H; Li W; Shi X
    Genes Dev; 2018 Jan; 32(1):58-69. PubMed ID: 29437725
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells.
    Arai S; Yoshimi A; Shimabe M; Ichikawa M; Nakagawa M; Imai Y; Goyama S; Kurokawa M
    Blood; 2011 Jun; 117(23):6304-14. PubMed ID: 21190993
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.