172 related articles for article (PubMed ID: 30066931)
1. NSD2 is downregulated in T2DM and promotes β cell proliferation and insulin secretion through the transcriptionally regulation of PDX1.
Shi S; Zhao L; Zheng L
Mol Med Rep; 2018 Sep; 18(3):3513-3520. PubMed ID: 30066931
[TBL] [Abstract][Full Text] [Related]
2. Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9.
Maganti AV; Maier B; Tersey SA; Sampley ML; Mosley AL; Özcan S; Pachaiyappan B; Woster PM; Hunter CS; Stein R; Mirmira RG
J Biol Chem; 2015 Apr; 290(15):9812-22. PubMed ID: 25713082
[TBL] [Abstract][Full Text] [Related]
3. Tshz1 Regulates Pancreatic β-Cell Maturation.
Raum JC; Soleimanpour SA; Groff DN; Coré N; Fasano L; Garratt AN; Dai C; Powers AC; Stoffers DA
Diabetes; 2015 Aug; 64(8):2905-14. PubMed ID: 25918232
[TBL] [Abstract][Full Text] [Related]
4. Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.
Wang X; Sterr M; Burtscher I; Chen S; Hieronimus A; Machicao F; Staiger H; Häring HU; Lederer G; Meitinger T; Cernilogar FM; Schotta G; Irmler M; Beckers J; Hrabě de Angelis M; Ray M; Wright CVE; Bakhti M; Lickert H
Mol Metab; 2018 Mar; 9():57-68. PubMed ID: 29396371
[TBL] [Abstract][Full Text] [Related]
5. Suppression of free fatty acid receptor 1 expression in pancreatic β-cells in obese type 2 diabetic db/db mice: a potential role of pancreatic and duodenal homeobox factor 1.
Kohara K; Obata A; Kimura T; Shimoda M; Moriuchi S; Okauchi S; Hirukawa H; Mune T; Kaku K; Kaneto H
Endocr J; 2019 Jan; 66(1):43-50. PubMed ID: 30333365
[TBL] [Abstract][Full Text] [Related]
6. Acarbose ameliorates spontaneous type‑2 diabetes in db/db mice by inhibiting PDX‑1 methylation.
Zhou D; Chen L; Mou X
Mol Med Rep; 2021 Jan; 23(1):. PubMed ID: 33236139
[TBL] [Abstract][Full Text] [Related]
7. Differentiation of Mouse Embryonic Stem Cells toward Functional Pancreatic β-Cell Surrogates through Epigenetic Regulation of Pdx1 by Nitric Oxide.
Salguero-Aranda C; Tapia-Limonchi R; Cahuana GM; Hitos AB; Diaz I; Hmadcha A; Fraga M; Martín F; Soria B; Tejedo JR; Bedoya FJ
Cell Transplant; 2016 Oct; 25(10):1879-1892. PubMed ID: 26980118
[TBL] [Abstract][Full Text] [Related]
8. miR-765 targeting PDX1 impairs pancreatic β-cell function to induce type 2 diabetes.
Zheng L; Wang Y; Li Y; Li L; Wang X; Li Y
Arch Physiol Biochem; 2023 Dec; 129(6):1279-1288. PubMed ID: 34357821
[TBL] [Abstract][Full Text] [Related]
9. RNA m6A reader IMP2/IGF2BP2 promotes pancreatic β-cell proliferation and insulin secretion by enhancing PDX1 expression.
Regué L; Zhao L; Ji F; Wang H; Avruch J; Dai N
Mol Metab; 2021 Jun; 48():101209. PubMed ID: 33705986
[TBL] [Abstract][Full Text] [Related]
10. Dracorhodin perchlorate protects pancreatic β-cells against glucotoxicity- or lipotoxicity-induced dysfunction and apoptosis in vitro and in vivo.
Liu L; Liang C; Mei P; Zhu H; Hou M; Yu C; Song Z; Bao Y; Huang Y; Yi J; Wang S; Wu Y; Zheng L; Sun Y; Wang G; Huo M; Yang S; Sun L; Li Y
FEBS J; 2019 Sep; 286(18):3718-3736. PubMed ID: 31349381
[TBL] [Abstract][Full Text] [Related]
11. A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin.
Sankaran SM; Wilkinson AW; Elias JE; Gozani O
J Biol Chem; 2016 Apr; 291(16):8465-74. PubMed ID: 26912663
[TBL] [Abstract][Full Text] [Related]
12. Coxsackievirus B Type 4 Infection in β Cells Downregulates the Chaperone Prefoldin URI to Induce a MODY4-like Diabetes via
Bernard H; Teijeiro A; Chaves-Pérez A; Perna C; Satish B; Novials A; Wang JP; Djouder N
Cell Rep Med; 2020 Oct; 1(7):100125. PubMed ID: 33205075
[TBL] [Abstract][Full Text] [Related]
13. Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes.
Wang J; Duan Z; Nugent Z; Zou JX; Borowsky AD; Zhang Y; Tepper CG; Li JJ; Fiehn O; Xu J; Kung HJ; Murphy LC; Chen HW
Cancer Lett; 2016 Aug; 378(2):69-79. PubMed ID: 27164560
[TBL] [Abstract][Full Text] [Related]
14. NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming.
Kuo AJ; Cheung P; Chen K; Zee BM; Kioi M; Lauring J; Xi Y; Park BH; Shi X; Garcia BA; Li W; Gozani O
Mol Cell; 2011 Nov; 44(4):609-20. PubMed ID: 22099308
[TBL] [Abstract][Full Text] [Related]
15. Impact of Pdx1-associated chromatin modifiers on islet β-cells.
Spaeth JM; Walker EM; Stein R
Diabetes Obes Metab; 2016 Sep; 18 Suppl 1(Suppl 1):123-7. PubMed ID: 27615141
[TBL] [Abstract][Full Text] [Related]
16. Effect of Silymarin in Pdx-1 expression and the proliferation of pancreatic β-cells in a pancreatectomy model.
Soto C; Raya L; Juárez J; Pérez J; González I
Phytomedicine; 2014 Feb; 21(3):233-9. PubMed ID: 24176839
[TBL] [Abstract][Full Text] [Related]
17. Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress.
Sachdeva MM; Claiborn KC; Khoo C; Yang J; Groff DN; Mirmira RG; Stoffers DA
Proc Natl Acad Sci U S A; 2009 Nov; 106(45):19090-5. PubMed ID: 19855005
[TBL] [Abstract][Full Text] [Related]
18. The histone methyltransferase, NSD2, enhances androgen receptor-mediated transcription.
Kang HB; Choi Y; Lee JM; Choi KC; Kim HC; Yoo JY; Lee YH; Yoon HG
FEBS Lett; 2009 Jun; 583(12):1880-6. PubMed ID: 19481544
[TBL] [Abstract][Full Text] [Related]
19. Dynamic regulation of pancreatic β cell function and gene expression by the SND1 coregulator
Kanojia S; Davidson RK; Conley JM; Xu J; Osmulski M; Sims EK; Ren H; Spaeth JM
Islets; 2023 Dec; 15(1):2267725. PubMed ID: 37838950
[TBL] [Abstract][Full Text] [Related]
20. Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes.
Fu Z; Gilbert ER; Liu D
Curr Diabetes Rev; 2013 Jan; 9(1):25-53. PubMed ID: 22974359
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
