222 related articles for article (PubMed ID: 30067827)
1. NorUDCA promotes degradation of α1-antitrypsin mutant Z protein by inducing autophagy through AMPK/ULK1 pathway.
Tang Y; Blomenkamp KS; Fickert P; Trauner M; Teckman JH
PLoS One; 2018; 13(8):e0200897. PubMed ID: 30067827
[TBL] [Abstract][Full Text] [Related]
2. Autophagy induced by exogenous bile acids is therapeutic in a model of α-1-AT deficiency liver disease.
Tang Y; Fickert P; Trauner M; Marcus N; Blomenkamp K; Teckman J
Am J Physiol Gastrointest Liver Physiol; 2016 Jul; 311(1):G156-65. PubMed ID: 27102560
[TBL] [Abstract][Full Text] [Related]
3. Accumulation of mutant alpha1-antitrypsin Z in the endoplasmic reticulum activates caspases-4 and -12, NFkappaB, and BAP31 but not the unfolded protein response.
Hidvegi T; Schmidt BZ; Hale P; Perlmutter DH
J Biol Chem; 2005 Nov; 280(47):39002-15. PubMed ID: 16183649
[TBL] [Abstract][Full Text] [Related]
4. Quantitative isolation of alphalAT mutant Z protein polymers from human and mouse livers and the effect of heat.
An JK; Blomenkamp K; Lindblad D; Teckman JH
Hepatology; 2005 Jan; 41(1):160-7. PubMed ID: 15619240
[TBL] [Abstract][Full Text] [Related]
5. Tris (1, 3-dichloro-2-propyl) phosphate induces apoptosis and autophagy in SH-SY5Y cells: Involvement of ROS-mediated AMPK/mTOR/ULK1 pathways.
Li R; Zhou P; Guo Y; Lee JS; Zhou B
Food Chem Toxicol; 2017 Feb; 100():183-196. PubMed ID: 28025121
[TBL] [Abstract][Full Text] [Related]
6. Lack of effect of oral 4-phenylbutyrate on serum alpha-1-antitrypsin in patients with alpha-1-antitrypsin deficiency: a preliminary study.
Teckman JH
J Pediatr Gastroenterol Nutr; 2004 Jul; 39(1):34-7. PubMed ID: 15187777
[TBL] [Abstract][Full Text] [Related]
7. Ubiquitin ligase SYVN1/HRD1 facilitates degradation of the SERPINA1 Z variant/α-1-antitrypsin Z variant via SQSTM1/p62-dependent selective autophagy.
Feng L; Zhang J; Zhu N; Ding Q; Zhang X; Yu J; Qiang W; Zhang Z; Ma Y; Huang D; Shen Y; Fang S; Yu Y; Wang H; Shen Y
Autophagy; 2017 Apr; 13(4):686-702. PubMed ID: 28121484
[TBL] [Abstract][Full Text] [Related]
8. α-amanitin induces autophagy through AMPK-mTOR-ULK1 signaling pathway in hepatocytes.
Xu Y; Wang S; Leung CK; Chen H; Wang C; Zhang H; Zhang S; Tan Y; Wang H; Miao L; Li Y; Huang Y; Zhang X; Yang G; Zhang R; Zeng X
Toxicol Lett; 2023 Jul; 383():89-97. PubMed ID: 37329965
[TBL] [Abstract][Full Text] [Related]
9. Baicalein induces autophagic cell death through AMPK/ULK1 activation and downregulation of mTORC1 complex components in human cancer cells.
Aryal P; Kim K; Park PH; Ham S; Cho J; Song K
FEBS J; 2014 Oct; 281(20):4644-58. PubMed ID: 25132405
[TBL] [Abstract][Full Text] [Related]
10. An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis.
Hidvegi T; Ewing M; Hale P; Dippold C; Beckett C; Kemp C; Maurice N; Mukherjee A; Goldbach C; Watkins S; Michalopoulos G; Perlmutter DH
Science; 2010 Jul; 329(5988):229-32. PubMed ID: 20522742
[TBL] [Abstract][Full Text] [Related]
11. ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis.
Chung SJ; Nagaraju GP; Nagalingam A; Muniraj N; Kuppusamy P; Walker A; Woo J; Győrffy B; Gabrielson E; Saxena NK; Sharma D
Autophagy; 2017 Aug; 13(8):1386-1403. PubMed ID: 28696138
[TBL] [Abstract][Full Text] [Related]
12. Energy metabolism disorder mediated ammonia gas-induced autophagy via AMPK/mTOR/ULK1-Beclin1 pathway in chicken livers.
Li Z; Miao Z; Ding L; Teng X; Bao J
Ecotoxicol Environ Saf; 2021 Jul; 217():112219. PubMed ID: 33853017
[TBL] [Abstract][Full Text] [Related]
13. Intracellular inclusions containing mutant alpha1-antitrypsin Z are propagated in the absence of autophagic activity.
Kamimoto T; Shoji S; Hidvegi T; Mizushima N; Umebayashi K; Perlmutter DH; Yoshimori T
J Biol Chem; 2006 Feb; 281(7):4467-76. PubMed ID: 16365039
[TBL] [Abstract][Full Text] [Related]
14. Induction of autophagy improves hepatic lipid metabolism in glucose-6-phosphatase deficiency.
Farah BL; Landau DJ; Sinha RA; Brooks ED; Wu Y; Fung SYS; Tanaka T; Hirayama M; Bay BH; Koeberl DD; Yen PM
J Hepatol; 2016 Feb; 64(2):370-379. PubMed ID: 26462884
[TBL] [Abstract][Full Text] [Related]
15. Rapamycin reduces intrahepatic alpha-1-antitrypsin mutant Z protein polymers and liver injury in a mouse model.
Kaushal S; Annamali M; Blomenkamp K; Rudnick D; Halloran D; Brunt EM; Teckman JH
Exp Biol Med (Maywood); 2010 Jun; 235(6):700-9. PubMed ID: 20511674
[TBL] [Abstract][Full Text] [Related]
16. Targeting intracellular degradation pathways for treatment of liver disease caused by α1-antitrypsin deficiency.
Wang Y; Perlmutter DH
Pediatr Res; 2014 Jan; 75(1-2):133-9. PubMed ID: 24226634
[TBL] [Abstract][Full Text] [Related]
17. AMPK-mTOR-ULK1 axis activation-dependent autophagy promotes hydroxycamptothecin-induced apoptosis in human bladder cancer cells.
Wang F; Cao M; Fan M; Wu H; Huang W; Zhang Y; Hu Z; Jin X
J Cell Physiol; 2020 May; 235(5):4302-4315. PubMed ID: 31621074
[TBL] [Abstract][Full Text] [Related]
18. The serine/threonine kinase ULK1 is a target of multiple phosphorylation events.
Bach M; Larance M; James DE; Ramm G
Biochem J; 2011 Dec; 440(2):283-91. PubMed ID: 21819378
[TBL] [Abstract][Full Text] [Related]
19. Alpha-1 antitrypsin and liver disease: mechanisms of injury and novel interventions.
Teckman JH; Mangalat N
Expert Rev Gastroenterol Hepatol; 2015 Feb; 9(2):261-8. PubMed ID: 25066184
[TBL] [Abstract][Full Text] [Related]
20. Indomethacin increases liver damage in a murine model of liver injury from alpha-1-antitrypsin deficiency.
Rudnick DA; Shikapwashya O; Blomenkamp K; Teckman JH
Hepatology; 2006 Oct; 44(4):976-82. PubMed ID: 17006946
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
