BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

339 related articles for article (PubMed ID: 30082494)

  • 1. PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival.
    Lu X; Fernando TM; Lossos C; Yusufova N; Liu F; Fontán L; Durant M; Geng H; Melnick J; Luo Y; Vega F; Moy V; Inghirami G; Nimer S; Melnick AM; Lossos IS
    Blood; 2018 Nov; 132(19):2026-2039. PubMed ID: 30082494
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Histone Arginine Methylation by PRMT7 Controls Germinal Center Formation via Regulating Bcl6 Transcription.
    Ying Z; Mei M; Zhang P; Liu C; He H; Gao F; Bao S
    J Immunol; 2015 Aug; 195(4):1538-47. PubMed ID: 26179907
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/β-catenin and AKT/GSK3β proliferative signaling.
    Chung J; Karkhanis V; Baiocchi RA; Sif S
    J Biol Chem; 2019 May; 294(19):7692-7710. PubMed ID: 30885941
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis.
    Hatzi K; Geng H; Doane AS; Meydan C; LaRiviere R; Cardenas M; Duy C; Shen H; Vidal MNC; Baslan T; Mohammad HP; Kruger RG; Shaknovich R; Haberman AM; Inghirami G; Lowe SW; Melnick AM
    Nat Immunol; 2019 Jan; 20(1):86-96. PubMed ID: 30538335
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Roles of BCL6 in normal and transformed germinal center B cells.
    Basso K; Dalla-Favera R
    Immunol Rev; 2012 May; 247(1):172-83. PubMed ID: 22500840
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Determining the Origin of Human Germinal Center B Cell-Derived Malignancies.
    Seifert M; Küppers R
    Methods Mol Biol; 2017; 1623():253-279. PubMed ID: 28589362
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MEF2B is a member of the BCL6 gene transcriptional complex and induces its expression in diffuse large B-cell lymphoma of the germinal center B-cell-like type.
    El Jamal SM; Grada Z; El Dinali MH; Zhou H; Hassan SY; Saad AG; Gibson B; Zhou X; Abulsayen HA; Khadra HS; Friedman J; Shalaby H; Kadi A; Megahed M; Emberesh M; Teruya-Feldstein J; Firpo-Betancourt A; Haikel Y; Fraig M; Hassan M
    Lab Invest; 2019 Apr; 99(4):539-550. PubMed ID: 30446717
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PRMT5 is upregulated by B-cell receptor signaling and forms a positive-feedback loop with PI3K/AKT in lymphoma cells.
    Zhu F; Guo H; Bates PD; Zhang S; Zhang H; Nomie KJ; Li Y; Lu L; Seibold KR; Wang F; Rumball I; Cameron H; Hoang NM; Yang DT; Xu W; Zhang L; Wang M; Capitini CM; Rui L
    Leukemia; 2019 Dec; 33(12):2898-2911. PubMed ID: 31123343
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kaiso is a key regulator of spleen germinal center formation by repressing Bcl6 expression in splenocytes.
    Koh DI; Yoon JH; Kim MK; An H; Kim MY; Hur MW
    Biochem Biophys Res Commun; 2013 Dec; 442(3-4):177-82. PubMed ID: 24269670
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PRMT5 is essential for B cell development and germinal center dynamics.
    Litzler LC; Zahn A; Meli AP; Hébert S; Patenaude AM; Methot SP; Sprumont A; Bois T; Kitamura D; Costantino S; King IL; Kleinman CL; Richard S; Di Noia JM
    Nat Commun; 2019 Jan; 10(1):22. PubMed ID: 30604754
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor complex 2 (PRC2) silencing.
    Chung J; Karkhanis V; Tae S; Yan F; Smith P; Ayers LW; Agostinelli C; Pileri S; Denis GV; Baiocchi RA; Sif S
    J Biol Chem; 2013 Dec; 288(49):35534-47. PubMed ID: 24189068
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BCL6-Mediated Silencing of PD-1 Ligands in Germinal Center B Cells Maintains Follicular T Cell Population.
    Peng C; Hu Q; Yang F; Zhang H; Li F; Huang C
    J Immunol; 2019 Feb; 202(3):704-713. PubMed ID: 30567732
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanisms of action of BCL6 during germinal center B cell development.
    Huang C; Melnick A
    Sci China Life Sci; 2015 Dec; 58(12):1226-32. PubMed ID: 26566802
    [TBL] [Abstract][Full Text] [Related]  

  • 14. BCL6 as a therapeutic target for lymphoma.
    Leeman-Neill RJ; Bhagat G
    Expert Opin Ther Targets; 2018 Feb; 22(2):143-152. PubMed ID: 29262721
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation.
    Sun D; Stopka-Farooqui U; Barry S; Aksoy E; Parsonage G; Vossenkämper A; Capasso M; Wan X; Norris S; Marshall JL; Clear A; Gribben J; MacDonald TT; Buckley CD; Korbonits M; Haworth O
    Cell Rep; 2019 Apr; 27(5):1461-1471.e4. PubMed ID: 31042473
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling.
    Haniuda K; Fukao S; Kitamura D
    Cell Rep; 2020 Nov; 33(5):108333. PubMed ID: 33147467
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation.
    Alinari L; Mahasenan KV; Yan F; Karkhanis V; Chung JH; Smith EM; Quinion C; Smith PL; Kim L; Patton JT; Lapalombella R; Yu B; Wu Y; Roy S; De Leo A; Pileri S; Agostinelli C; Ayers L; Bradner JE; Chen-Kiang S; Elemento O; Motiwala T; Majumder S; Byrd JC; Jacob S; Sif S; Li C; Baiocchi RA
    Blood; 2015 Apr; 125(16):2530-43. PubMed ID: 25742700
    [TBL] [Abstract][Full Text] [Related]  

  • 18. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.
    Béguelin W; Teater M; Gearhart MD; Calvo Fernández MT; Goldstein RL; Cárdenas MG; Hatzi K; Rosen M; Shen H; Corcoran CM; Hamline MY; Gascoyne RD; Levine RL; Abdel-Wahab O; Licht JD; Shaknovich R; Elemento O; Bardwell VJ; Melnick AM
    Cancer Cell; 2016 Aug; 30(2):197-213. PubMed ID: 27505670
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BCL6: master regulator of the germinal center reaction and key oncogene in B cell lymphomagenesis.
    Basso K; Dalla-Favera R
    Adv Immunol; 2010; 105():193-210. PubMed ID: 20510734
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells.
    Basso K; Saito M; Sumazin P; Margolin AA; Wang K; Lim WK; Kitagawa Y; Schneider C; Alvarez MJ; Califano A; Dalla-Favera R
    Blood; 2010 Feb; 115(5):975-84. PubMed ID: 19965633
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.