242 related articles for article (PubMed ID: 30086184)
1. Two mutations at different positions in the CNBH domain of the hERG channel accelerate deactivation and impair the interaction with the EAG domain.
Kume S; Shimomura T; Tateyama M; Kubo Y
J Physiol; 2018 Oct; 596(19):4629-4650. PubMed ID: 30086184
[TBL] [Abstract][Full Text] [Related]
2. Direct interaction of eag domains and cyclic nucleotide-binding homology domains regulate deactivation gating in hERG channels.
Gianulis EC; Liu Q; Trudeau MC
J Gen Physiol; 2013 Oct; 142(4):351-66. PubMed ID: 24043860
[TBL] [Abstract][Full Text] [Related]
3. Conformation-sensitive antibody reveals an altered cytosolic PAS/CNBh assembly during hERG channel gating.
Harley CA; Bernardo-Seisdedos G; Stevens-Sostre WA; Jones DK; Azevedo MM; Sampaio P; Lorga-Gomes M; Trudeau MC; Millet O; Robertson GA; Morais-Cabral JH
Proc Natl Acad Sci U S A; 2021 Nov; 118(44):. PubMed ID: 34716268
[TBL] [Abstract][Full Text] [Related]
4. A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels.
Gustina AS; Trudeau MC
Proc Natl Acad Sci U S A; 2009 Aug; 106(31):13082-7. PubMed ID: 19651618
[TBL] [Abstract][Full Text] [Related]
5. Investigation of PAS and CNBH domain interactions in hERG channels and effects of long-QT syndrome-causing mutations with surface plasmon resonance.
Soohoo SM; Tiwari PB; Suzuki YJ; Brelidze TI
J Biol Chem; 2022 Jan; 298(1):101433. PubMed ID: 34801551
[TBL] [Abstract][Full Text] [Related]
6. hERG potassium channel gating is mediated by N- and C-terminal region interactions.
Gustina AS; Trudeau MC
J Gen Physiol; 2011 Mar; 137(3):315-25. PubMed ID: 21357734
[TBL] [Abstract][Full Text] [Related]
7. The eag domain regulates hERG channel inactivation gating via a direct interaction.
Gustina AS; Trudeau MC
J Gen Physiol; 2013 Feb; 141(2):229-41. PubMed ID: 23319729
[TBL] [Abstract][Full Text] [Related]
8. Voltage-dependent activation in EAG channels follows a ligand-receptor rather than a mechanical-lever mechanism.
Malak OA; Gluhov GS; Grizel AV; Kudryashova KS; Sokolova OS; Loussouarn G
J Biol Chem; 2019 Apr; 294(16):6506-6521. PubMed ID: 30808709
[TBL] [Abstract][Full Text] [Related]
9. Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels.
Ng CA; Phan K; Hill AP; Vandenberg JI; Perry MD
J Biol Chem; 2014 Sep; 289(37):25822-32. PubMed ID: 25074935
[TBL] [Abstract][Full Text] [Related]
10. Mechanistic insight into human ether-à-go-go-related gene (hERG) K+ channel deactivation gating from the solution structure of the EAG domain.
Muskett FW; Thouta S; Thomson SJ; Bowen A; Stansfeld PJ; Mitcheson JS
J Biol Chem; 2011 Feb; 286(8):6184-91. PubMed ID: 21135103
[TBL] [Abstract][Full Text] [Related]
11. Molecular determinants of interactions between the N-terminal domain and the transmembrane core that modulate hERG K+ channel gating.
Fernández-Trillo J; Barros F; Machín A; Carretero L; Domínguez P; de la Peña P
PLoS One; 2011; 6(9):e24674. PubMed ID: 21935437
[TBL] [Abstract][Full Text] [Related]
12. The hERG potassium channel intrinsic ligand regulates N- and C-terminal interactions and channel closure.
Codding SJ; Trudeau MC
J Gen Physiol; 2019 Apr; 151(4):478-488. PubMed ID: 30425124
[TBL] [Abstract][Full Text] [Related]
13. Chlorpromazine binding to the PAS domains uncovers the effect of ligand modulation on EAG channel activity.
Wang ZJ; Soohoo SM; Tiwari PB; Piszczek G; Brelidze TI
J Biol Chem; 2020 Mar; 295(13):4114-4123. PubMed ID: 32047112
[TBL] [Abstract][Full Text] [Related]
14. Differences between ion binding to eag and HERG voltage sensors contribute to differential regulation of activation and deactivation gating.
Lin MC; Papazian DM
Channels (Austin); 2007; 1(6):429-37. PubMed ID: 18690045
[TBL] [Abstract][Full Text] [Related]
15. Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels.
Clarke CE; Hill AP; Zhao J; Kondo M; Subbiah RN; Campbell TJ; Vandenberg JI
J Physiol; 2006 Jun; 573(Pt 2):291-304. PubMed ID: 16556651
[TBL] [Abstract][Full Text] [Related]
16. Identification of undecylenic acid as EAG channel inhibitor using surface plasmon resonance-based screen of KCNH channels.
Wang ZJ; Tiwari PB; Üren A; Brelidze TI
BMC Pharmacol Toxicol; 2019 Jul; 20(1):42. PubMed ID: 31315662
[TBL] [Abstract][Full Text] [Related]
17. Differential effects of amino-terminal distal and proximal domains in the regulation of human erg K(+) channel gating.
Viloria CG; Barros F; Giráldez T; Gómez-Varela D; de la Peña P
Biophys J; 2000 Jul; 79(1):231-46. PubMed ID: 10866950
[TBL] [Abstract][Full Text] [Related]
18. Eag Domains Regulate LQT Mutant hERG Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Liu QN; Trudeau MC
PLoS One; 2015; 10(4):e0123951. PubMed ID: 25923442
[TBL] [Abstract][Full Text] [Related]
19. HERG potassium channel regulation by the N-terminal eag domain.
Gustina AS; Trudeau MC
Cell Signal; 2012 Aug; 24(8):1592-8. PubMed ID: 22522181
[TBL] [Abstract][Full Text] [Related]
20. Structure of the Cyclic Nucleotide-Binding Homology Domain of the hERG Channel and Its Insight into Type 2 Long QT Syndrome.
Li Y; Ng HQ; Li Q; Kang C
Sci Rep; 2016 Mar; 6():23712. PubMed ID: 27025590
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]