BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

275 related articles for article (PubMed ID: 30086232)

  • 1. Amyloidogenicity, Cytotoxicity, and Receptor Activity of Bovine Amylin: Implications for Xenobiotic Transplantation and the Design of Nontoxic Amylin Variants.
    Akter R; Bower RL; Abedini A; Schmidt AM; Hay DL; Raleigh DP
    ACS Chem Biol; 2018 Sep; 13(9):2747-2757. PubMed ID: 30086232
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analysis of Amylin Consensus Sequences Suggests That Human Amylin Is Not Optimized to Minimize Amyloid Formation and Provides Clues to Factors That Modulate Amyloidogenicity.
    Noh D; Bower RL; Hay DL; Zhyvoloup A; Raleigh DP
    ACS Chem Biol; 2020 Jun; 15(6):1408-1416. PubMed ID: 32364695
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Analysis of Prairie Vole Amylin Reveals the Importance of the N-Terminus and Residue 22 in Amyloidogenicity and Cytotoxicity.
    Lee KH; Noh D; Zhyvoloup A; Raleigh D
    Biochemistry; 2020 Feb; 59(4):471-478. PubMed ID: 31777253
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Amyloidogenicity and cytotoxicity of des-Lys-1 human amylin provides insight into amylin self-assembly and highlights the difficulties of defining amyloidogenicity.
    Lee KH; Zhyvoloup A; Raleigh D
    Protein Eng Des Sel; 2019 Dec; 32(2):87-93. PubMed ID: 31768548
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Analysis of Baboon IAPP Provides Insight into Amyloidogenicity and Cytotoxicity of Human IAPP.
    Ridgway Z; Lee KH; Zhyvoloup A; Wong A; Eldrid C; Hannaberry E; Thalassinos K; Abedini A; Raleigh DP
    Biophys J; 2020 Mar; 118(5):1142-1151. PubMed ID: 32105649
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Analysis of the Amyloidogenic Potential of Pufferfish (Takifugu rubripes) Islet Amyloid Polypeptide Highlights the Limitations of Thioflavin-T Assays and the Difficulties in Defining Amyloidogenicity.
    Wong AG; Wu C; Hannaberry E; Watson MD; Shea JE; Raleigh DP
    Biochemistry; 2016 Jan; 55(3):510-8. PubMed ID: 26694855
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Analysis of the ability of pramlintide to inhibit amyloid formation by human islet amyloid polypeptide reveals a balance between optimal recognition and reduced amyloidogenicity.
    Wang H; Ridgway Z; Cao P; Ruzsicska B; Raleigh DP
    Biochemistry; 2015 Nov; 54(44):6704-11. PubMed ID: 26407043
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Islet amyloid: from fundamental biophysics to mechanisms of cytotoxicity.
    Cao P; Marek P; Noor H; Patsalo V; Tu LH; Wang H; Abedini A; Raleigh DP
    FEBS Lett; 2013 Apr; 587(8):1106-18. PubMed ID: 23380070
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Analysis of Proline Substitutions Reveals the Plasticity and Sequence Sensitivity of Human IAPP Amyloidogenicity and Toxicity.
    Ridgway Z; Eldrid C; Zhyvoloup A; Ben-Younis A; Noh D; Thalassinos K; Raleigh DP
    Biochemistry; 2020 Feb; 59(6):742-754. PubMed ID: 31922743
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of a hinge residue controlling islet amyloid polypeptide self-assembly and cytotoxicity.
    Godin E; Nguyen PT; Zottig X; Bourgault S
    J Biol Chem; 2019 May; 294(21):8452-8463. PubMed ID: 30975901
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology.
    Akter R; Cao P; Noor H; Ridgway Z; Tu LH; Wang H; Wong AG; Zhang X; Abedini A; Schmidt AM; Raleigh DP
    J Diabetes Res; 2016; 2016():2798269. PubMed ID: 26649319
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Complete characterization of the mutation landscape reveals the effect on amylin stability and amyloidogenicity.
    Smaoui MR; Waldispühl J
    Proteins; 2015 Jun; 83(6):1014-26. PubMed ID: 25809921
    [TBL] [Abstract][Full Text] [Related]  

  • 13. On the importance of being amidated: Analysis of the role of the conserved C-terminal amide of amylin in amyloid formation and cytotoxicity.
    Yang T; Filippov I; Manathunga L; Baghai A; Maréchal A; Raleigh DP; Zhyvoloup A
    Biophys Chem; 2024 Apr; 307():107168. PubMed ID: 38367541
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dual role of interleukin-1β in islet amyloid formation and its β-cell toxicity: Implications for type 2 diabetes and islet transplantation.
    Park YJ; Warnock GL; Ao Z; Safikhan N; Meloche M; Asadi A; Kieffer TJ; Marzban L
    Diabetes Obes Metab; 2017 May; 19(5):682-694. PubMed ID: 28058779
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanisms of islet amyloidosis toxicity in type 2 diabetes.
    Abedini A; Schmidt AM
    FEBS Lett; 2013 Apr; 587(8):1119-27. PubMed ID: 23337872
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analysis of Sheep and Goat IAPP Provides Insight into IAPP Amyloidogenicity and Cytotoxicity.
    Miller MET; Li MH; Baghai A; Peetz VH; Zhyvoloup A; Raleigh DP
    Biochemistry; 2022 Nov; 61(22):2531-2545. PubMed ID: 36286531
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human Amylin: From Pathology to Physiology and Pharmacology.
    Ling W; Huang YM; Qiao YC; Zhang XX; Zhao HL
    Curr Protein Pept Sci; 2019; 20(9):944-957. PubMed ID: 30919775
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ferret islet amyloid polypeptide (IAPP): characterization of in vitro and in vivo amyloidogenicity.
    Paulsson JF; Benoit-Biancamano MO; Schäffer L; Dahl K
    Amyloid; 2011 Dec; 18(4):222-8. PubMed ID: 22047620
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aggregation of islet amyloid polypeptide: from physical chemistry to cell biology.
    Cao P; Abedini A; Raleigh DP
    Curr Opin Struct Biol; 2013 Feb; 23(1):82-9. PubMed ID: 23266002
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets.
    Meier DT; Entrup L; Templin AT; Hogan MF; Mellati M; Zraika S; Hull RL; Kahn SE
    Diabetologia; 2016 Oct; 59(10):2166-71. PubMed ID: 27393137
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.