233 related articles for article (PubMed ID: 30088262)
1. Induction of apoptosis via proteasome inhibition in leukemia/lymphoma cells by two potent piperidones.
Contreras L; Calderon RI; Varela-Ramirez A; Zhang HY; Quan Y; Das U; Dimmock JR; Skouta R; Aguilera RJ
Cell Oncol (Dordr); 2018 Dec; 41(6):623-636. PubMed ID: 30088262
[TBL] [Abstract][Full Text] [Related]
2. Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms.
Contreras L; Medina S; Schiaffino Bustamante AY; Borrego EA; Valenzuela CA; Das U; Karki SS; Dimmock JR; Aguilera RJ
Pharmacol Rep; 2022 Feb; 74(1):159-174. PubMed ID: 34448104
[TBL] [Abstract][Full Text] [Related]
3. Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines.
Swain RM; Contreras L; Varela-Ramirez A; Hossain M; Das U; Valenzuela CA; Penichet ML; Dimmock JR; Aguilera RJ
Invest New Drugs; 2022 Oct; 40(5):905-921. PubMed ID: 35793039
[TBL] [Abstract][Full Text] [Related]
4. Bortezomib-mediated downregulation of S-phase kinase protein-2 (SKP2) causes apoptotic cell death in chronic myelogenous leukemia cells.
Iskandarani A; Bhat AA; Siveen KS; Prabhu KS; Kuttikrishnan S; Khan MA; Krishnankutty R; Kulinski M; Nasr RR; Mohammad RM; Uddin S
J Transl Med; 2016 Mar; 14():69. PubMed ID: 26956626
[TBL] [Abstract][Full Text] [Related]
5. Targeted inhibition of the deubiquitinating enzymes, USP14 and UCHL5, induces proteotoxic stress and apoptosis in Waldenström macroglobulinaemia tumour cells.
Chitta K; Paulus A; Akhtar S; Blake MK; Caulfield TR; Novak AJ; Ansell SM; Advani P; Ailawadhi S; Sher T; Linder S; Chanan-Khan A
Br J Haematol; 2015 May; 169(3):377-90. PubMed ID: 25691154
[TBL] [Abstract][Full Text] [Related]
6. Ritonavir, nelfinavir, saquinavir and lopinavir induce proteotoxic stress in acute myeloid leukemia cells and sensitize them for proteasome inhibitor treatment at low micromolar drug concentrations.
Kraus M; Müller-Ide H; Rückrich T; Bader J; Overkleeft H; Driessen C
Leuk Res; 2014 Mar; 38(3):383-92. PubMed ID: 24418752
[TBL] [Abstract][Full Text] [Related]
7. A novel class of piperidones exhibit potent, selective and pro-apoptotic anti-leukemia properties.
Nunes LM; Hossain M; Varela-Ramirez A; DAS U; Ayala-Marin YM; Dimmock JR; Aguilera RJ
Oncol Lett; 2016 Jun; 11(6):3842-3848. PubMed ID: 27313705
[TBL] [Abstract][Full Text] [Related]
8. The deubiquitinase inhibitor b-AP15 induces strong proteotoxic stress and mitochondrial damage.
Zhang X; Pellegrini P; Saei AA; Hillert EK; Mazurkiewicz M; Olofsson MH; Zubarev RA; D'Arcy P; Linder S
Biochem Pharmacol; 2018 Oct; 156():291-301. PubMed ID: 30149015
[TBL] [Abstract][Full Text] [Related]
9. Determination of differentially regulated proteins upon proteasome inhibition in AML cell lines by the combination of large-scale and targeted quantitative proteomics.
Matondo M; Marcellin M; Chaoui K; Bousquet-Dubouch MP; Gonzalez-de-Peredo A; Monsarrat B; Burlet-Schiltz O
Proteomics; 2017 Apr; 17(7):. PubMed ID: 27709814
[TBL] [Abstract][Full Text] [Related]
10. Small-molecule RA-9 inhibits proteasome-associated DUBs and ovarian cancer in vitro and in vivo via exacerbating unfolded protein responses.
Coughlin K; Anchoori R; Iizuka Y; Meints J; MacNeill L; Vogel RI; Orlowski RZ; Lee MK; Roden RB; Bazzaro M
Clin Cancer Res; 2014 Jun; 20(12):3174-86. PubMed ID: 24727327
[TBL] [Abstract][Full Text] [Related]
11. Proteasome inhibitors abolish cell death downstream of caspase activation during anti-microtubule drug-induced apoptosis in leukemia cells.
Nagy K; Petak I; Imre G; Barna G; Gezane-Csorba M; Sebestyen A; Houghton JA; Mihalik R; Kopper L
Anticancer Res; 2005; 25(5):3321-6. PubMed ID: 16101145
[TBL] [Abstract][Full Text] [Related]
12. Proteasome inhibition induces both pro- and anti-cell death pathways in prostate cancer cells.
Yang W; Monroe J; Zhang Y; George D; Bremer E; Li H
Cancer Lett; 2006 Nov; 243(2):217-27. PubMed ID: 16413676
[TBL] [Abstract][Full Text] [Related]
13. Selective activation of TNFR1 and NF-κB inhibition by a novel biyouyanagin analogue promotes apoptosis in acute leukemia cells.
Savva CG; Totokotsopoulos S; Nicolaou KC; Neophytou CM; Constantinou AI
BMC Cancer; 2016 Apr; 16():279. PubMed ID: 27098354
[TBL] [Abstract][Full Text] [Related]
14. The proton pump inhibitor pantoprazole disrupts protein degradation systems and sensitizes cancer cells to death under various stresses.
Cao Y; Chen M; Tang D; Yan H; Ding X; Zhou F; Zhang M; Xu G; Zhang W; Zhang S; Zhuge Y; Wang L; Zou X
Cell Death Dis; 2018 May; 9(6):604. PubMed ID: 29789637
[TBL] [Abstract][Full Text] [Related]
15. Anticancer activity of cryptotanshinone on acute lymphoblastic leukemia cells.
Wu CF; Klauck SM; Efferth T
Arch Toxicol; 2016 Sep; 90(9):2275-2286. PubMed ID: 26564229
[TBL] [Abstract][Full Text] [Related]
16. LukS-PV induces mitochondrial-mediated apoptosis and G0/G1 cell cycle arrest in human acute myeloid leukemia THP-1 cells.
Bu S; Xie Q; Chang W; Huo X; Chen F; Ma X
Int J Biochem Cell Biol; 2013 Aug; 45(8):1531-7. PubMed ID: 23702031
[TBL] [Abstract][Full Text] [Related]
17. Increased expression and altered subunit composition of proteasomes induced by continuous proteasome inhibition establish apoptosis resistance and hyperproliferation of Burkitt lymphoma cells.
Fuchs D; Berges C; Opelz G; Daniel V; Naujokat C
J Cell Biochem; 2008 Jan; 103(1):270-83. PubMed ID: 17516511
[TBL] [Abstract][Full Text] [Related]
18. The role of the ubiquitin proteasome system in lymphoma.
Suh KS; Tanaka T; Sarojini S; Nightingale G; Gharbaran R; Pecora A; Goy A
Crit Rev Oncol Hematol; 2013 Sep; 87(3):306-22. PubMed ID: 23541070
[TBL] [Abstract][Full Text] [Related]
19. Elevation of proteasomal substrate levels sensitizes cells to apoptosis induced by inhibition of proteasomal deubiquitinases.
Sun C; Roboti P; Puumalainen MR; Fryknäs M; Wang X; D'Arcy P; Hult M; High S; Linder S; Swanton E
PLoS One; 2014; 9(10):e108839. PubMed ID: 25286379
[TBL] [Abstract][Full Text] [Related]
20. New insights into the molecular mechanisms underlying sensitivity/resistance to the atypical retinoid ST1926 in acute myeloid leukaemia cells: the role of histone H2A.Z, cAMP-dependent protein kinase A and the proteasome.
Fratelli M; Fisher JN; Paroni G; Di Francesco AM; Pierri F; Pisano C; Godl K; Marx S; Tebbe A; Valli C; Gianni M; Stravalaci M; Gobbi M; Terao M; Garattini E
Eur J Cancer; 2013 Apr; 49(6):1491-500. PubMed ID: 23245330
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]