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2. BDNF contributes to the development of neuropathic pain by induction of spinal long-term potentiation via SHP2 associated GluN2B-containing NMDA receptors activation in rats with spinal nerve ligation. Ding X; Cai J; Li S; Liu XD; Wan Y; Xing GG Neurobiol Dis; 2015 Jan; 73():428-51. PubMed ID: 25447233 [TBL] [Abstract][Full Text] [Related]
3. Noonan syndrome-associated SHP2 mutation differentially modulates the expression of postsynaptic receptors according to developmental maturation. Oh JY; Rhee S; Silva AJ; Lee YS; Kim HK Neurosci Lett; 2017 May; 649():41-47. PubMed ID: 28366775 [TBL] [Abstract][Full Text] [Related]
4. Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature. De Rocca Serra-Nédélec A; Edouard T; Tréguer K; Tajan M; Araki T; Dance M; Mus M; Montagner A; Tauber M; Salles JP; Valet P; Neel BG; Raynal P; Yart A Proc Natl Acad Sci U S A; 2012 Mar; 109(11):4257-62. PubMed ID: 22371576 [TBL] [Abstract][Full Text] [Related]
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6. Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome. Krenz M; Gulick J; Osinska HE; Colbert MC; Molkentin JD; Robbins J Proc Natl Acad Sci U S A; 2008 Dec; 105(48):18930-5. PubMed ID: 19017799 [TBL] [Abstract][Full Text] [Related]
7. PZR coordinates Shp2 Noonan and LEOPARD syndrome signaling in zebrafish and mice. Paardekooper Overman J; Yi JS; Bonetti M; Soulsby M; Preisinger C; Stokes MP; Hui L; Silva JC; Overvoorde J; Giansanti P; Heck AJ; Kontaridis MI; den Hertog J; Bennett AM Mol Cell Biol; 2014 Aug; 34(15):2874-89. PubMed ID: 24865967 [TBL] [Abstract][Full Text] [Related]
8. Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects. Solman M; Blokzijl-Franke S; Piques F; Yan C; Yang Q; Strullu M; Kamel SM; Ak P; Bakkers J; Langenau DM; Cavé H; den Hertog J Elife; 2022 May; 11():. PubMed ID: 35535491 [TBL] [Abstract][Full Text] [Related]
9. Gain-of-function mutations in the gene encoding the tyrosine phosphatase SHP2 induce hydrocephalus in a catalytically dependent manner. Zheng H; Yu WM; Waclaw RR; Kontaridis MI; Neel BG; Qu CK Sci Signal; 2018 Mar; 11(522):. PubMed ID: 29559584 [TBL] [Abstract][Full Text] [Related]
10. SHP2 mutations induce precocious gliogenesis of Noonan syndrome-derived iPSCs during neural development in vitro. Ju Y; Park JS; Kim D; Kim B; Lee JH; Nam Y; Yoo HW; Lee BH; Han YM Stem Cell Res Ther; 2020 Jun; 11(1):209. PubMed ID: 32493428 [TBL] [Abstract][Full Text] [Related]
11. SHP2 sails from physiology to pathology. Tajan M; de Rocca Serra A; Valet P; Edouard T; Yart A Eur J Med Genet; 2015 Oct; 58(10):509-25. PubMed ID: 26341048 [TBL] [Abstract][Full Text] [Related]
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13. Involvement of EphA2-mediated tyrosine phosphorylation of Shp2 in Shp2-regulated activation of extracellular signal-regulated kinase. Miura K; Wakayama Y; Tanino M; Orba Y; Sawa H; Hatakeyama M; Tanaka S; Sabe H; Mochizuki N Oncogene; 2013 Nov; 32(45):5292-301. PubMed ID: 23318428 [TBL] [Abstract][Full Text] [Related]
14. The Noonan syndrome-associated D61G variant of the protein tyrosine phosphatase SHP2 prevents synaptic down-scaling. Lu W; Ai H; Xue F; Luan Y; Zhang B J Biol Chem; 2020 Jul; 295(29):10023-10031. PubMed ID: 32499374 [TBL] [Abstract][Full Text] [Related]
15. Developmental SHP2 dysfunction underlies cardiac hypertrophy in Noonan syndrome with multiple lentigines. Lauriol J; Cabrera JR; Roy A; Keith K; Hough SM; Damilano F; Wang B; Segarra GC; Flessa ME; Miller LE; Das S; Bronson R; Lee KH; Kontaridis MI J Clin Invest; 2016 Aug; 126(8):2989-3005. PubMed ID: 27348588 [TBL] [Abstract][Full Text] [Related]
16. Noonan syndrome-causing SHP2 mutants impair ERK-dependent chondrocyte differentiation during endochondral bone growth. Tajan M; Pernin-Grandjean J; Beton N; Gennero I; Capilla F; Neel BG; Araki T; Valet P; Tauber M; Salles JP; Yart A; Edouard T Hum Mol Genet; 2018 Jul; 27(13):2276-2289. PubMed ID: 29659837 [TBL] [Abstract][Full Text] [Related]
17. Protein tyrosine phosphatase SHP2/PTPN11 mistargeting as a consequence of SH2-domain point mutations associated with Noonan Syndrome and leukemia. Müller PJ; Rigbolt KT; Paterok D; Piehler J; Vanselow J; Lasonder E; Andersen JS; Schaper F; Sobota RM J Proteomics; 2013 Jun; 84():132-47. PubMed ID: 23584145 [TBL] [Abstract][Full Text] [Related]
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