BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 30099457)

  • 1. A pan-NADPH Oxidase Inhibitor Ameliorates Kidney Injury in Type 1 Diabetic Rats.
    Dorotea D; Kwon G; Lee JH; Saunders E; Bae YS; Moon SH; Lee SJ; Cha DR; Ha H
    Pharmacology; 2018; 102(3-4):180-189. PubMed ID: 30099457
    [TBL] [Abstract][Full Text] [Related]  

  • 2. APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury.
    Cha JJ; Min HS; Kim KT; Kim JE; Ghee JY; Kim HW; Lee JE; Han JY; Lee G; Ha HJ; Bae YS; Lee SR; Moon SH; Lee SC; Kim G; Kang YS; Cha DR
    Lab Invest; 2017 Apr; 97(4):419-431. PubMed ID: 28165467
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes.
    Gorin Y; Cavaglieri RC; Khazim K; Lee DY; Bruno F; Thakur S; Fanti P; Szyndralewiez C; Barnes JL; Block K; Abboud HE
    Am J Physiol Renal Physiol; 2015 Jun; 308(11):F1276-87. PubMed ID: 25656366
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy.
    Jha JC; Gray SP; Barit D; Okabe J; El-Osta A; Namikoshi T; Thallas-Bonke V; Wingler K; Szyndralewiez C; Heitz F; Touyz RM; Cooper ME; Schmidt HH; Jandeleit-Dahm KA
    J Am Soc Nephrol; 2014 Jun; 25(6):1237-54. PubMed ID: 24511132
    [TBL] [Abstract][Full Text] [Related]  

  • 5. APX-115, a pan-NADPH oxidase inhibitor, protects development of diabetic nephropathy in podocyte specific NOX5 transgenic mice.
    Lee ES; Kim HM; Lee SH; Ha KB; Bae YS; Lee SJ; Moon SH; Lee EY; Lee JH; Chung CH
    Free Radic Biol Med; 2020 Dec; 161():92-101. PubMed ID: 33011273
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis.
    Kwon G; Uddin MJ; Lee G; Jiang S; Cho A; Lee JH; Lee SR; Bae YS; Moon SH; Lee SJ; Cha DR; Ha H
    Oncotarget; 2017 Sep; 8(43):74217-74232. PubMed ID: 29088780
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deletion of soluble epoxide hydrolase gene improves renal endothelial function and reduces renal inflammation and injury in streptozotocin-induced type 1 diabetes.
    Elmarakby AA; Faulkner J; Al-Shabrawey M; Wang MH; Maddipati KR; Imig JD
    Am J Physiol Regul Integr Comp Physiol; 2011 Nov; 301(5):R1307-17. PubMed ID: 21832210
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Combined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno- and atheroprotection even in established micro- and macrovascular disease.
    Gray SP; Jha JC; Kennedy K; van Bommel E; Chew P; Szyndralewiez C; Touyz RM; Schmidt HHHW; Cooper ME; Jandeleit-Dahm KAM
    Diabetologia; 2017 May; 60(5):927-937. PubMed ID: 28160092
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Apigenin ameliorates streptozotocin-induced diabetic nephropathy in rats via MAPK-NF-κB-TNF-α and TGF-β1-MAPK-fibronectin pathways.
    Malik S; Suchal K; Khan SI; Bhatia J; Kishore K; Dinda AK; Arya DS
    Am J Physiol Renal Physiol; 2017 Aug; 313(2):F414-F422. PubMed ID: 28566504
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chronic tempol treatment attenuates the renal hemodynamic effects induced by a heme oxygenase inhibitor in streptozotocin diabetic rats.
    Rodriguez F; Lopez B; Perez C; Fenoy FJ; Hernandez I; Stec DE; Li Volti G; Salom MG
    Am J Physiol Regul Integr Comp Physiol; 2011 Nov; 301(5):R1540-8. PubMed ID: 21849637
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The superoxide dismutase mimetic tempol blunts diabetes-induced upregulation of NADPH oxidase and endoplasmic reticulum stress in a rat model of diabetic nephropathy.
    De Blasio MJ; Ramalingam A; Cao AH; Prakoso D; Ye JM; Pickering R; Watson AMD; de Haan JB; Kaye DM; Ritchie RH
    Eur J Pharmacol; 2017 Jul; 807():12-20. PubMed ID: 28438648
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Puerarin attenuates diabetic kidney injury through the suppression of NOX4 expression in podocytes.
    Li X; Cai W; Lee K; Liu B; Deng Y; Chen Y; Zhang X; He JC; Zhong Y
    Sci Rep; 2017 Nov; 7(1):14603. PubMed ID: 29097815
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Korean red ginseng attenuates hyperglycemia-induced renal inflammation and fibrosis via accelerated autophagy and protects against diabetic kidney disease.
    Karunasagara S; Hong GL; Park SR; Lee NH; Jung DY; Kim TW; Jung JY
    J Ethnopharmacol; 2020 May; 254():112693. PubMed ID: 32112899
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Naringin ameliorates diabetic nephropathy by inhibiting NADPH oxidase 4.
    Zhang J; Yang S; Li H; Chen F; Shi J
    Eur J Pharmacol; 2017 Jun; 804():1-6. PubMed ID: 28395989
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease.
    Ilatovskaya DV; Blass G; Palygin O; Levchenko V; Pavlov TS; Grzybowski MN; Winsor K; Shuyskiy LS; Geurts AM; Cowley AW; Birnbaumer L; Staruschenko A
    J Am Soc Nephrol; 2018 Jul; 29(7):1917-1927. PubMed ID: 29793963
    [No Abstract]   [Full Text] [Related]  

  • 16. Pan-Src kinase inhibitor treatment attenuates diabetic kidney injury via inhibition of Fyn kinase-mediated endoplasmic reticulum stress.
    Dorotea D; Jiang S; Pak ES; Son JB; Choi HG; Ahn SM; Ha H
    Exp Mol Med; 2022 Aug; 54(8):1086-1097. PubMed ID: 35918533
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury.
    Noh H; Oh EY; Seo JY; Yu MR; Kim YO; Ha H; Lee HB
    Am J Physiol Renal Physiol; 2009 Sep; 297(3):F729-39. PubMed ID: 19553350
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy.
    Jha JC; Thallas-Bonke V; Banal C; Gray SP; Chow BS; Ramm G; Quaggin SE; Cooper ME; Schmidt HH; Jandeleit-Dahm KA
    Diabetologia; 2016 Feb; 59(2):379-89. PubMed ID: 26508318
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RAAS inhibitors directly reduce diabetes-induced renal fibrosis via growth factor inhibition.
    Koszegi S; Molnar A; Lenart L; Hodrea J; Balogh DB; Lakat T; Szkibinszkij E; Hosszu A; Sparding N; Genovese F; Wagner L; Vannay A; Szabo AJ; Fekete A
    J Physiol; 2019 Jan; 597(1):193-209. PubMed ID: 30324679
    [TBL] [Abstract][Full Text] [Related]  

  • 20. APX-115A, a pan-NADPH Oxidase Inhibitor, Induces Caspase-dependent Cell Death by Suppressing NOX4-ROS Signaling in EBV-infected Retinal Epithelial Cells.
    Hong SW; Noh MH; Kim YS; Jin DH; Moon SH; Yang JW; Hur DY
    Curr Eye Res; 2020 Sep; 45(9):1136-1143. PubMed ID: 31951764
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.