BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 30103751)

  • 1. Metabolism of primaquine in normal human volunteers: investigation of phase I and phase II metabolites from plasma and urine using ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry.
    Avula B; Tekwani BL; Chaurasiya ND; Fasinu P; Dhammika Nanayakkara NP; Bhandara Herath HMT; Wang YH; Bae JY; Khan SI; Elsohly MA; McChesney JD; Zimmerman PA; Khan IA; Walker LA
    Malar J; 2018 Aug; 17(1):294. PubMed ID: 30103751
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Profiling primaquine metabolites in primary human hepatocytes using UHPLC-QTOF-MS with 13C stable isotope labeling.
    Avula B; Tekwani BL; Chaurasiya ND; Nanayakkara NP; Wang YH; Khan SI; Adelli VR; Sahu R; Elsohly MA; McChesney JD; Khan IA; Walker LA
    J Mass Spectrom; 2013 Feb; 48(2):276-85. PubMed ID: 23378100
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytes.
    Fasinu PS; Avula B; Tekwani BL; Nanayakkara NP; Wang YH; Bandara Herath HM; McChesney JD; Reichard GA; Marcsisin SR; Elsohly MA; Khan SI; Khan IA; Walker LA
    Malar J; 2016 Apr; 15():224. PubMed ID: 27093859
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pathway-specific inhibition of primaquine metabolism by chloroquine/quinine.
    Fasinu PS; Tekwani BL; Avula B; Chaurasiya ND; Nanayakkara NP; Wang YH; Khan IA; Walker LA
    Malar J; 2016 Sep; 15(1):466. PubMed ID: 27618912
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enantioselective metabolism of primaquine by human CYP2D6.
    Fasinu PS; Tekwani BL; Nanayakkara NP; Avula B; Herath HM; Wang YH; Adelli VR; Elsohly MA; Khan SI; Khan IA; Pybus BS; Marcsisin SR; Reichard GA; McChesney JD; Walker LA
    Malar J; 2014 Dec; 13():507. PubMed ID: 25518709
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.
    Spring MD; Sousa JC; Li Q; Darko CA; Morrison MN; Marcsisin SR; Mills KT; Potter BM; Paolino KM; Twomey PS; Moon JE; Tosh DM; Cicatelli SB; Froude JW; Pybus BS; Oliver TG; McCarthy WF; Waters NC; Smith PL; Reichard GA; Bennett JW
    J Infect Dis; 2019 Oct; 220(11):1761-1770. PubMed ID: 31549155
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine.
    Pybus BS; Sousa JC; Jin X; Ferguson JA; Christian RE; Barnhart R; Vuong C; Sciotti RJ; Reichard GA; Kozar MP; Walker LA; Ohrt C; Melendez V
    Malar J; 2012 Aug; 11():259. PubMed ID: 22856549
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enantioselective pharmacokinetics of primaquine in healthy human volunteers.
    Tekwani BL; Avula B; Sahu R; Chaurasiya ND; Khan SI; Jain S; Fasinu PS; Herath HM; Stanford D; Nanayakkara NP; McChesney JD; Yates TW; ElSohly MA; Khan IA; Walker LA
    Drug Metab Dispos; 2015 Apr; 43(4):571-7. PubMed ID: 25637634
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantitative analysis of primaquine and its metabolites in human urine using liquid chromatography coupled with tandem mass spectrometry.
    Khan W; Wang YH; Dhammika Nanayakkara NP; Bandara Herath HMT; Chaurasiya ND; Tekwani BL; ElSohly MA; McChesney JD; Khan IA; Walker LA
    J Chromatogr B Analyt Technol Biomed Life Sci; 2022 Dec; 1213():123517. PubMed ID: 36343612
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An LC-MS based study of the metabolic profile of primaquine, an 8-aminoquinoline antiparasitic drug, with an in vitro primary human hepatocyte culture model.
    Jin X; Pybus BS; Marcsisin R; Logan T; Luong TL; Sousa J; Matlock N; Collazo V; Asher C; Carroll D; Olmeda R; Walker LA; Kozar MP; Melendez V
    Eur J Drug Metab Pharmacokinet; 2014 Jun; 39(2):139-46. PubMed ID: 23797843
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparative single dose pharmacokinetics and metabolism of racemic primaquine and its enantiomers in human volunteers.
    Khan W; Wang YH; Chaurasiya ND; Nanayakkara ND; Herath HB; Harrison KA; Dale G; Stanford DA; Dahl EP; McChesney JD; Gul W; ElSohly MA; Khan SI; Fasinu PS; Khan IA; Tekwani BL; Walker LA
    Drug Metab Pharmacokinet; 2022 Aug; 45():100463. PubMed ID: 35709685
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The conversion of primaquine into primaquine-aldehyde, primaquine-alcohol, and carboxyprimaquine, a major plasma metabolite.
    Frischer H; Mellovitz RL; Ahmad T; Nora MV
    J Lab Clin Med; 1991 Jun; 117(6):468-76. PubMed ID: 2045714
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Quantitative determination of primaquine-5,6-ortho-quinone and carboxyprimaquine-5,6-ortho-quinone in human erythrocytes by UHPLC-MS/MS.
    Khan W; Wang YH; Nanayakkara NPD; Herath HMTB; Catchings Z; Khan S; Fasinu PS; ElSohly MA; McChesney JD; Khan IA; Chaurasiya ND; Tekwani BL; Walker LA
    J Chromatogr B Analyt Technol Biomed Life Sci; 2021 Jan; 1163():122510. PubMed ID: 33387859
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Population pharmacokinetics of primaquine and its metabolites in African males.
    Chotsiri P; Mahamar A; Diawara H; Fasinu PS; Diarra K; Sanogo K; Bousema T; Walker LA; Brown JM; Dicko A; Gosling R; Chen I; Tarning J
    Malar J; 2024 May; 23(1):159. PubMed ID: 38773528
    [TBL] [Abstract][Full Text] [Related]  

  • 15.
    Pett H; Bradley J; Okebe J; Dicko A; Tiono AB; Gonçalves BP; Stone W; Chen I; Lanke K; Neuvonen M; Mustaniemi AL; Eziefula AC; Gosling R; D'Alessandro U; Drakeley C; Niemi M; Bousema T
    Antimicrob Agents Chemother; 2019 Oct; 63(10):. PubMed ID: 31383656
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparative pharmacokinetics and tissue distribution of primaquine enantiomers in mice.
    Fasinu PS; Chaurasiya ND; Dhammika Nanayakkara NP; Wang YH; Bandara Herath HMT; Avula B; McChesney JD; Jollow D; Walker LA; Tekwani BL
    Malar J; 2022 Feb; 21(1):33. PubMed ID: 35123453
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Comparative metabolism and tolerability of racemic primaquine and its enantiomers in human volunteers during 7-day administration.
    Khan W; Wang YH; Chaurasiya ND; Nanayakkara NPD; Bandara Herath HM; Harrison KA; Dale G; Stanford DA; Dahl EP; McChesney JD; Gul W; ElSohly MA; Jollow D; Tekwani BL; Walker LA
    Front Pharmacol; 2022; 13():1104735. PubMed ID: 36726785
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tafenoquine treatment of Plasmodium vivax malaria: suggestive evidence that CYP2D6 reduced metabolism is not associated with relapse in the Phase 2b DETECTIVE trial.
    St Jean PL; Xue Z; Carter N; Koh GC; Duparc S; Taylor M; Beaumont C; Llanos-Cuentas A; Rueangweerayut R; Krudsood S; Green JA; Rubio JP
    Malar J; 2016 Feb; 15():97. PubMed ID: 26888075
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A newly validated high-performance liquid chromatography method with diode array ultraviolet detection for analysis of the antimalarial drug primaquine in the blood plasma.
    Carmo APBD; Borborema M; Ribeiro S; De-Oliveira ACX; Paumgartten FJR; Moreira DL
    Rev Soc Bras Med Trop; 2017; 50(4):499-505. PubMed ID: 28954071
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Simplified and Rapid Determination of Primaquine and 5,6-Orthoquinone Primaquine by UHPLC-MS/MS: Its Application to a Pharmacokinetic Study.
    Pookmanee W; Thongthip S; Tankanitlert J; Mungthin M; Sukasem C; Wittayalertpanya S
    Molecules; 2021 Jul; 26(14):. PubMed ID: 34299634
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.