These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 30108835)

  • 1. Pyrazolo[3,4-
    Díaz JL; Corbera J; Martínez D; Bordas M; Sicre C; Pascual R; Pretel MJ; Marín AP; Montero A; Dordal A; Alvarez I; Almansa C
    Medchemcomm; 2017 Jun; 8(6):1246-1254. PubMed ID: 30108835
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pyrazolo[3,4-
    Díaz JL; Corbera J; Cuberes R; Contijoch M; Enrech R; Yeste S; Montero A; Dordal A; Monroy X; Almansa C
    Medchemcomm; 2017 Jun; 8(6):1235-1245. PubMed ID: 30108834
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel object recognition test as an alternative approach to assessing the pharmacological profile of sigma-1 receptor ligands.
    Szczepańska K; Bojarski AJ; Popik P; Malikowska-Racia N
    Pharmacol Rep; 2023 Oct; 75(5):1291-1298. PubMed ID: 37572216
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of New Benzylpiperazine Derivatives as σ
    Romeo G; Bonanno F; Wilson LL; Arena E; Modica MN; Pittalà V; Salerno L; Prezzavento O; McLaughlin JP; Intagliata S
    ACS Chem Neurosci; 2021 Jun; 12(11):2003-2012. PubMed ID: 34019387
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of novel 6,7-dihydro-5H-cyclopenta[d]pyrimidine and 5,6,7,8-tetrahydroquinazoline derivatives as sigma-1 (σ1) receptor antagonists for the treatment of pain.
    Lan Y; Songyang Y; Zhang L; Peng Y; Song J
    Bioorg Med Chem Lett; 2016 Apr; 26(8):2051-6. PubMed ID: 26947609
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain.
    Lan Y; Chen Y; Cao X; Zhang J; Wang J; Xu X; Qiu Y; Zhang T; Liu X; Liu BF; Zhang G
    J Med Chem; 2014 Dec; 57(24):10404-23. PubMed ID: 25420090
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and biological evaluation of C9- and C2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as new A2A and A3 adenosine receptors antagonists.
    Baraldi PG; Fruttarolo F; Tabrizi MA; Preti D; Romagnoli R; El-Kashef H; Moorman A; Varani K; Gessi S; Merighi S; Borea PA
    J Med Chem; 2003 Mar; 46(7):1229-41. PubMed ID: 12646033
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural refinement of pyrazolo[4,3-d]pyrimidine derivatives to obtain highly potent and selective antagonists for the human A3 adenosine receptor.
    Squarcialupi L; Catarzi D; Varano F; Betti M; Falsini M; Vincenzi F; Ravani A; Ciancetta A; Varani K; Moro S; Colotta V
    Eur J Med Chem; 2016 Jan; 108():117-133. PubMed ID: 26638043
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H
    Szczepańska K; Podlewska S; Dichiara M; Gentile D; Patamia V; Rosier N; Mönnich D; Ruiz Cantero MC; Karcz T; Łażewska D; Siwek A; Pockes S; Cobos EJ; Marrazzo A; Stark H; Rescifina A; Bojarski AJ; Amata E; Kieć-Kononowicz K
    ACS Chem Neurosci; 2022 Jan; 13(1):1-15. PubMed ID: 34908391
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exploring the Selectivity Profile of Sigma Receptor Ligands by Molecular Docking and Pharmacophore Analyses.
    Righetti G; Tonelli M; Fossa P; Cichero E
    Med Chem; 2021; 17(10):1151-1165. PubMed ID: 33155928
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 7-Amino-2-phenylpyrazolo[4,3-d]pyrimidine derivatives: structural investigations at the 5-position to target human A₁ and A(2A) adenosine receptors. Molecular modeling and pharmacological studies.
    Squarcialupi L; Colotta V; Catarzi D; Varano F; Betti M; Varani K; Vincenzi F; Borea PA; Porta N; Ciancetta A; Moro S
    Eur J Med Chem; 2014 Sep; 84():614-27. PubMed ID: 25063944
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 2,6-diazaspiro[3.4]octan-7-one derivatives as potent sigma-1 receptor antagonists that enhanced the antinociceptive effect of morphine and rescued morphine tolerance.
    Fu K; Xu W; Yang R; Zhao H; Xu H; Wei Y; Liu H; Qiu Y; Chen D; Guo D; Xiong B
    Eur J Med Chem; 2023 Mar; 249():115178. PubMed ID: 36753922
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Exploiting the Power of Stereochemistry in Drug Action: 3-[(2
    Turnaturi R; Pasquinucci L; Chiechio S; Grasso M; Marrazzo A; Amata E; Dichiara M; Prezzavento O; Parenti C
    ACS Chem Neurosci; 2020 Apr; 11(7):999-1005. PubMed ID: 32186844
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of a new series of hexahydro-2H-pyrano[3,2-c]quinolines as novel selective σ1 receptor ligands.
    Díaz JL; Christmann U; Fernández A; Luengo M; Bordas M; Enrech R; Carro M; Pascual R; Burgueño J; Merlos M; Benet-Buchholz J; Cerón-Bertran J; Ramírez J; Reinoso RF; Fernández de Henestrosa AR; Vela JM; Almansa C
    J Med Chem; 2013 May; 56(9):3656-65. PubMed ID: 23560650
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Investigating isoindoline, tetrahydroisoquinoline, and tetrahydrobenzazepine scaffolds for their sigma receptor binding properties.
    Linkens K; Schmidt HR; Sahn JJ; Kruse AC; Martin SF
    Eur J Med Chem; 2018 May; 151():557-567. PubMed ID: 29656199
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of some novel pyrazolopyrimidines incorporating a benzothiazole ring system.
    Azam MA; Dharanya L; Mehta CC; Sachdeva S
    Acta Pharm; 2013 Mar; 63(1):19-30. PubMed ID: 23482310
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Does the combination of optimal substitutions at the C²-, N⁵- and N⁸-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A₃ adenosine receptors?
    Cheong SL; Dolzhenko AV; Paoletta S; Lee EP; Kachler S; Federico S; Klotz KN; Dolzhenko AV; Spalluto G; Moro S; Pastorin G
    Bioorg Med Chem; 2011 Oct; 19(20):6120-34. PubMed ID: 21908194
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacological profiling of sigma 1 receptor ligands by novel receptor homomer assays.
    Yano H; Bonifazi A; Xu M; Guthrie DA; Schneck SN; Abramyan AM; Fant AD; Hong WC; Newman AH; Shi L
    Neuropharmacology; 2018 May; 133():264-275. PubMed ID: 29407216
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A facile and novel synthesis of N(2)-, C(6)-substituted pyrazolo[3,4-d]pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists.
    Venkatesan G; Paira P; Cheong SL; Federico S; Klotz KN; Spalluto G; Pastorin G
    Eur J Med Chem; 2015 Mar; 92():784-98. PubMed ID: 25633494
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Investigational sigma-1 receptor antagonists for the treatment of pain.
    Vela JM; Merlos M; Almansa C
    Expert Opin Investig Drugs; 2015; 24(7):883-96. PubMed ID: 26037209
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.