BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

338 related articles for article (PubMed ID: 30111667)

  • 101. Design, synthesis and biological evaluation of 3,4-diaryl-1,2,5-oxadiazole-2/5-oxides as highly potent inhibitors of tubulin polymerization.
    Hong Y; Zhao Y; Yang L; Gao M; Li L; Man S; Wang Z; Guan Q; Bao K; Zuo D; Wu Y; Zhang W
    Eur J Med Chem; 2019 Sep; 178():287-296. PubMed ID: 31195170
    [TBL] [Abstract][Full Text] [Related]  

  • 102. Novel pyrazolopyrimidines: Synthesis, in vitro cytotoxic activity and mechanistic investigation.
    Hassan GS; Abdel Rahman DE; Nissan YM; Abdelmajeed EA; Abdelghany TM
    Eur J Med Chem; 2017 Sep; 138():565-576. PubMed ID: 28704759
    [TBL] [Abstract][Full Text] [Related]  

  • 103. Synthesis and anticancer activity of new dihydropyrimidinone derivatives.
    Mostafa AS; Selim KB
    Eur J Med Chem; 2018 Aug; 156():304-315. PubMed ID: 30015070
    [TBL] [Abstract][Full Text] [Related]  

  • 104. Novel [(3-indolylmethylene)hydrazono]indolin-2-ones as apoptotic anti-proliferative agents: design, synthesis and in vitro biological evaluation.
    Eldehna WM; Abo-Ashour MF; Ibrahim HS; Al-Ansary GH; Ghabbour HA; Elaasser MM; Ahmed HYA; Safwat NA
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):686-700. PubMed ID: 29560733
    [TBL] [Abstract][Full Text] [Related]  

  • 105. Design, synthesis and antiproliferative activity of novel 5-nitropyrimidine-2,4-diamine derivatives bearing alkyl acetate moiety.
    Zhao PL; Li YH; Yang HK; Chen P; Zhang B; Sun Q; Li Q; You WW
    Eur J Med Chem; 2016 Aug; 118():161-9. PubMed ID: 27128180
    [TBL] [Abstract][Full Text] [Related]  

  • 106. Eco-friendly synthesis of novel cyanopyridine derivatives and their anticancer and PIM-1 kinase inhibitory activities.
    Abouzid KAM; Al-Ansary GH; El-Naggar AM
    Eur J Med Chem; 2017 Jul; 134():357-365. PubMed ID: 28431341
    [TBL] [Abstract][Full Text] [Related]  

  • 107. Design, synthesis and biological evaluation of novel pyrimidine, 3-cyanopyridine and m-amino-N-phenylbenzamide based monocyclic EGFR tyrosine kinase inhibitors.
    Mao Y; Zhu W; Kong X; Wang Z; Xie H; Ding J; Terrett NK; Shen J; Shen J
    Bioorg Med Chem; 2013 Jun; 21(11):3090-104. PubMed ID: 23602524
    [TBL] [Abstract][Full Text] [Related]  

  • 108. Synthesis and anticancer activity evaluation of novel azacalix[2]arene[2]pyrimidines.
    Addepalli Y; Yang X; Zhou M; Reddy DP; Zhang SL; Wang Z; He Y
    Eur J Med Chem; 2018 May; 151():214-225. PubMed ID: 29614418
    [TBL] [Abstract][Full Text] [Related]  

  • 109. Cryptolepine and aromathecin based mimics as potent G-quadruplex-binding, DNA-cleavage and anticancer agents: Design, synthesis and DNA targeting-induced apoptosis.
    Yuan JM; Wei K; Zhang GH; Chen NY; Wei XW; Pan CX; Mo DL; Su GF
    Eur J Med Chem; 2019 May; 169():144-158. PubMed ID: 30875505
    [TBL] [Abstract][Full Text] [Related]  

  • 110. Design, Synthesis of New Pyridine and Pyrimidine Sugar Compounds as Antagonists Targeting the ERα via Structure-Based Virtual Screening.
    Nassar IF; El-Sayed WA; Ragab TIM; Shalaby ASG; Mehany ABM
    Mini Rev Med Chem; 2019; 19(5):395-409. PubMed ID: 30124151
    [TBL] [Abstract][Full Text] [Related]  

  • 111. Design, synthesis, antitumor activities and biological studies of novel diaryl substituted fused heterocycles as dual ligands targeting tubulin and katanin.
    Gao F; Liang Y; Zhou P; Cheng J; Ding K; Wang Y
    Eur J Med Chem; 2019 Sep; 178():177-194. PubMed ID: 31185410
    [TBL] [Abstract][Full Text] [Related]  

  • 112. Design, synthesis and in vitro antitumor activity of novel N-substituted-4-phenyl/benzylphthalazin-1-ones.
    Eldehna WM; Ibrahim HS; Abdel-Aziz HA; Farrag NN; Youssef MM
    Eur J Med Chem; 2015 Jan; 89():549-60. PubMed ID: 25462265
    [TBL] [Abstract][Full Text] [Related]  

  • 113. Spirohydantoins and 1,2,4-triazole-3-carboxamide derivatives as inhibitors of histone deacetylase: Design, synthesis, and biological evaluation.
    Aboeldahab AMA; Beshr EAM; Shoman ME; Rabea SM; Aly OM
    Eur J Med Chem; 2018 Feb; 146():79-92. PubMed ID: 29396364
    [TBL] [Abstract][Full Text] [Related]  

  • 114. Discovery of 9H-purins as potential tubulin polymerization inhibitors: Synthesis, biological evaluation and structure-activity relationships.
    Zhou ZZ; Shi XD; Feng HF; Cheng YF; Wang HT; Xu JP
    Eur J Med Chem; 2017 Sep; 138():1126-1134. PubMed ID: 28763647
    [TBL] [Abstract][Full Text] [Related]  

  • 115. Design and synthesis of imidazo[2,1-b]thiazole-chalcone conjugates: microtubule-destabilizing agents.
    Kamal A; Balakrishna M; Nayak VL; Shaik TB; Faazil S; Nimbarte VD
    ChemMedChem; 2014 Dec; 9(12):2766-80. PubMed ID: 25313981
    [TBL] [Abstract][Full Text] [Related]  

  • 116. Thienopyrimidine derivatives exert their anticancer efficacy via apoptosis induction, oxidative stress and mitotic catastrophe.
    Amawi H; Karthikeyan C; Pathak R; Hussein N; Christman R; Robey R; Ashby CR; Trivedi P; Malhotra A; Tiwari AK
    Eur J Med Chem; 2017 Sep; 138():1053-1065. PubMed ID: 28759878
    [TBL] [Abstract][Full Text] [Related]  

  • 117. Design, Synthesis and Antiproliferative Activities of Oxidative Stress Inducers Based on 2-Styryl-3,5-dihydro-4H-imidazol-4-one Scaffold.
    Omar AM; Abdelghany TM; Abdel-Bakky MS; Alahdal AM; Radwan MF; El-Araby ME
    Chem Pharm Bull (Tokyo); 2018 Oct; 66(10):967-975. PubMed ID: 30047515
    [TBL] [Abstract][Full Text] [Related]  

  • 118. Design, synthesis and bioevaluation of antitubulin agents carrying diaryl-5,5-fused-heterocycle scaffold.
    Xu Q; Sun M; Bai Z; Wang Y; Wu Y; Tian H; Zuo D; Guan Q; Bao K; Wu Y; Zhang W
    Eur J Med Chem; 2017 Oct; 139():242-249. PubMed ID: 28802124
    [TBL] [Abstract][Full Text] [Related]  

  • 119. Design, synthesis and bioevaluation of dihydropyrazolo[3,4-b]pyridine and benzo[4,5]imidazo[1,2-a]pyrimidine compounds as dual KSP and Aurora-A kinase inhibitors for anti-cancer agents.
    Fu RG; You QD; Yang L; Wu WT; Jiang C; Xu XL
    Bioorg Med Chem; 2010 Nov; 18(22):8035-43. PubMed ID: 20934346
    [TBL] [Abstract][Full Text] [Related]  

  • 120. Synthesis and biological evaluation of quinoline analogues of flavones as potential anticancer agents and tubulin polymerization inhibitors.
    Shobeiri N; Rashedi M; Mosaffa F; Zarghi A; Ghandadi M; Ghasemi A; Ghodsi R
    Eur J Med Chem; 2016 May; 114():14-23. PubMed ID: 26974371
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.