187 related articles for article (PubMed ID: 30113702)
1. Identification of canine cytochrome P-450s (CYPs) metabolizing the tramadol (+)-M1 and (+)-M2 metabolites to the tramadol (+)-M5 metabolite in dog liver microsomes.
Perez Jimenez TE; Mealey KL; Schnider D; Grubb TL; Greene SA; Court MH
J Vet Pharmacol Ther; 2018 Dec; 41(6):815-824. PubMed ID: 30113702
[TBL] [Abstract][Full Text] [Related]
2. Tramadol metabolism to O-desmethyl tramadol (M1) and N-desmethyl tramadol (M2) by dog liver microsomes: Species comparison and identification of responsible canine cytochrome P-450s (CYPs).
Perez Jimenez TE; Mealey KL; Grubb TL; Greene SA; Court MH
Drug Metab Dispos; 2016 Dec; 44(12):1963-1972. PubMed ID: 27758804
[TBL] [Abstract][Full Text] [Related]
3. Identification of cytochrome P-450 isoforms responsible for cis-tramadol metabolism in human liver microsomes.
Subrahmanyam V; Renwick AB; Walters DG; Young PJ; Price RJ; Tonelli AP; Lake BG
Drug Metab Dispos; 2001 Aug; 29(8):1146-55. PubMed ID: 11454734
[TBL] [Abstract][Full Text] [Related]
4. Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability.
Martinez SE; Shi J; Zhu HJ; Perez Jimenez TE; Zhu Z; Court MH
Drug Metab Dispos; 2019 Nov; 47(11):1314-1324. PubMed ID: 31427433
[TBL] [Abstract][Full Text] [Related]
5. Evidence for propofol hydroxylation by cytochrome P4502B11 in canine liver microsomes: breed and gender differences.
Hay Kraus BL; Greenblatt DJ; Venkatakrishnan K; Court MH
Xenobiotica; 2000 Jun; 30(6):575-88. PubMed ID: 10923860
[TBL] [Abstract][Full Text] [Related]
6. Pharmacogenomics of poor drug metabolism in Greyhounds: Cytochrome P450 (CYP) 2B11 genetic variation, breed distribution, and functional characterization.
Martinez SE; Andresen MC; Zhu Z; Papageorgiou I; Court MH
Sci Rep; 2020 Jan; 10(1):69. PubMed ID: 31919457
[TBL] [Abstract][Full Text] [Related]
7. Oral Coadministration of Fluconazole with Tramadol Markedly Increases Plasma and Urine Concentrations of Tramadol and the
Perez Jimenez TE; Kukanich B; Joo H; Mealey KL; Grubb TL; Greene SA; Court MH
Drug Metab Dispos; 2019 Jan; 47(1):15-25. PubMed ID: 30366901
[TBL] [Abstract][Full Text] [Related]
8. Cytochrome P450-mediated hepatic metabolism of new fluorescent substrates in cats and dogs.
van Beusekom CD; Schipper L; Fink-Gremmels J
J Vet Pharmacol Ther; 2010 Dec; 33(6):519-27. PubMed ID: 21062303
[TBL] [Abstract][Full Text] [Related]
9. In vitro metabolism of tirilazad mesylate in male and female rats. Contribution of cytochrome P4502C11 and delta 4-5 alpha-reductase.
Wienkers LC; Steenwyk RC; Mizsak SA; Pearson PG
Drug Metab Dispos; 1995 Mar; 23(3):383-92. PubMed ID: 7628305
[TBL] [Abstract][Full Text] [Related]
10. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
Niwa T; Shiraga T; Mitani Y; Terakawa M; Tokuma Y; Kagayama A
Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
[TBL] [Abstract][Full Text] [Related]
11. Comparative pharmacokinetic profile of cimicoxib in dogs and cats after IV administration.
Schneider M; Dron F; Cuinet E; Woehrlé F
Vet J; 2021 Apr; 270():105625. PubMed ID: 33641805
[TBL] [Abstract][Full Text] [Related]
12. Cannabidiol and cannabidiolic acid: Preliminary in vitro evaluation of metabolism and drug-drug interactions involving canine cytochrome P-450, UDP-glucuronosyltransferase, and P-glycoprotein.
Court MH; Mealey KL; Burke NS; Jimenez TP; Zhu Z; Wakshlag JJ
J Vet Pharmacol Ther; 2024 Jan; 47(1):1-13. PubMed ID: 37469115
[TBL] [Abstract][Full Text] [Related]
13. Cytochrome P450 reaction phenotyping of itraconazole hydroxylation in the dog.
Tonero ME; Li Z; Reinhart JM
J Vet Pharmacol Ther; 2022 May; 45(3):255-264. PubMed ID: 35389533
[TBL] [Abstract][Full Text] [Related]
14. Selective inhibition of dog hepatic CYP2B11 and CYP3A12.
Lu P; Singh SB; Carr BA; Fang Y; Xiang CD; Rushmore TH; Rodrigues AD; Shou M
J Pharmacol Exp Ther; 2005 May; 313(2):518-28. PubMed ID: 15677349
[TBL] [Abstract][Full Text] [Related]
15. Metabolism of ropinirole is mediated by several canine CYP enzymes.
Tervahauta T; Uutela P; Koskinen M
Vet Med Sci; 2023 Jul; 9(4):1584-1591. PubMed ID: 37317989
[TBL] [Abstract][Full Text] [Related]
16. Canine CYP2B11 metabolizes and is inhibited by anesthetic agents often co-administered in dogs.
Baratta MT; Zaya MJ; White JA; Locuson CW
J Vet Pharmacol Ther; 2010 Feb; 33(1):50-5. PubMed ID: 20444025
[TBL] [Abstract][Full Text] [Related]
17. Pharmacokinetic and urine profile of tramadol and its major metabolites following oral immediate release capsules administration in dogs.
Giorgi M; Del Carlo S; Saccomanni G; Łebkowska-Wieruszewska B; Kowalski CJ
Vet Res Commun; 2009 Dec; 33(8):875-85. PubMed ID: 19533402
[TBL] [Abstract][Full Text] [Related]
18. Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil.
Hyland R; Roe EG; Jones BC; Smith DA
Br J Clin Pharmacol; 2001 Mar; 51(3):239-48. PubMed ID: 11298070
[TBL] [Abstract][Full Text] [Related]
19. In vitro identification of metabolic pathways and cytochrome P450 enzymes involved in the metabolism of etoperidone.
Yan Z; Caldwell GW; Wu WN; McKown LA; Rafferty B; Jones W; Masucci JA
Xenobiotica; 2002 Nov; 32(11):949-62. PubMed ID: 12487725
[TBL] [Abstract][Full Text] [Related]
20. Evidence for polymorphism in the canine metabolism of the cyclooxygenase 2 inhibitor, celecoxib.
Paulson SK; Engel L; Reitz B; Bolten S; Burton EG; Maziasz TJ; Yan B; Schoenhard GL
Drug Metab Dispos; 1999 Oct; 27(10):1133-42. PubMed ID: 10497139
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
