These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
141 related articles for article (PubMed ID: 30113716)
1. 3-(7-Azaindolyl)-4-indolylmaleimides as a novel class of mutant isocitrate dehydrogenase-1 inhibitors: Design, synthesis, and biological evaluation. Hu Y; Gao A; Liao H; Zhang M; Xu G; Gao L; Xu L; Zhou Y; Gao J; Ye Q; Li J Arch Pharm (Weinheim); 2018 Oct; 351(10):e1800039. PubMed ID: 30113716 [TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological evaluation of 3-aryl-4-indolyl-maleimides as potent mutant isocitrate dehydrogenase-1 inhibitors. Liu X; Hu Y; Gao A; Xu M; Gao L; Xu L; Zhou Y; Gao J; Ye Q; Li J Bioorg Med Chem; 2019 Feb; 27(4):589-603. PubMed ID: 30600148 [TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and biological activity of 3-pyrazine-2-yl-oxazolidin-2-ones as novel, potent and selective inhibitors of mutant isocitrate dehydrogenase 1. Ma T; Zou F; Pusch S; Yang L; Zhu Q; Xu Y; Gu Y; von Deimling A; Zha X Bioorg Med Chem; 2017 Dec; 25(24):6379-6387. PubMed ID: 29089260 [TBL] [Abstract][Full Text] [Related]
4. Inhibition of Mutated Isocitrate Dehydrogenase 1 in Cancer. Wu F; Cheng G; Yao Y; Kogiso M; Jiang H; Li XN; Song Y Med Chem; 2018; 14(7):715-724. PubMed ID: 29792149 [TBL] [Abstract][Full Text] [Related]
5. Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors. Zheng Q; Tang S; Fu X; Chen Z; Ye Y; Lan X; Jiang L; Huang Y; Ding J; Geng M; Huang M; Wan H Bioorg Med Chem Lett; 2017 Dec; 27(23):5262-5266. PubMed ID: 29079473 [TBL] [Abstract][Full Text] [Related]
6. Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells. Jones S; Ahmet J; Ayton K; Ball M; Cockerill M; Fairweather E; Hamilton N; Harper P; Hitchin J; Jordan A; Levy C; Lopez R; McKenzie E; Packer M; Plant D; Simpson I; Simpson P; Sinclair I; Somervaille TC; Small H; Spencer GJ; Thomson G; Tonge M; Waddell I; Walsh J; Waszkowycz B; Wigglesworth M; Wiseman DH; Ogilvie D J Med Chem; 2016 Dec; 59(24):11120-11137. PubMed ID: 28002956 [TBL] [Abstract][Full Text] [Related]
7. Inhibition of cancer-associated mutant isocitrate dehydrogenases: synthesis, structure-activity relationship, and selective antitumor activity. Liu Z; Yao Y; Kogiso M; Zheng B; Deng L; Qiu JJ; Dong S; Lv H; Gallo JM; Li XN; Song Y J Med Chem; 2014 Oct; 57(20):8307-18. PubMed ID: 25271760 [TBL] [Abstract][Full Text] [Related]
8. Discovery of linear unnatural peptides as potent mutant isocitrate dehydrogenase 1 inhibitors by Ugi reaction. Zhou X; Zheng M; Zhao N; Hu Y; Yang K; Huo J; Liu G; Huang J; Chen L; Zhou Y; Li H Bioorg Chem; 2022 Feb; 119():105569. PubMed ID: 34954572 [TBL] [Abstract][Full Text] [Related]
9. Radiolabeled inhibitors as probes for imaging mutant IDH1 expression in gliomas: Synthesis and preliminary evaluation of labeled butyl-phenyl sulfonamide analogs. Chitneni SK; Reitman ZJ; Gooden DM; Yan H; Zalutsky MR Eur J Med Chem; 2016 Aug; 119():218-30. PubMed ID: 27163884 [TBL] [Abstract][Full Text] [Related]
10. Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening. Duan Z; Liu J; Niu L; Wang J; Feng M; Chen H; Luo C Bioorg Med Chem; 2019 Aug; 27(15):3229-3236. PubMed ID: 31208797 [TBL] [Abstract][Full Text] [Related]
11. Identification and Characterization of Small-Molecule Inhibitors of the R132H/R132H Mutant Isocitrate Dehydrogenase 1 Homodimer and R132H/Wild-Type Heterodimer. Brooks E; Wu X; Hanel A; Nguyen S; Wang J; Zhang JH; Harrison A; Zhang W J Biomol Screen; 2014 Sep; 19(8):1193-200. PubMed ID: 24980596 [TBL] [Abstract][Full Text] [Related]
12. Discovery and structure-activity-relationship study of novel imidazole cyclopropyl amine analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors. Zheng Q; Chen Z; Wan H; Tang S; Ye Y; Xu Y; Jiang L; Ding J; Geng M; Huang M; Huang Y Bioorg Med Chem Lett; 2018 Dec; 28(23-24):3808-3812. PubMed ID: 30413349 [TBL] [Abstract][Full Text] [Related]
14. Discovery of novel natural-product-derived mutant isocitrate dehydrogenases 1 inhibitors: Structure-based virtual screening, biological evaluation and structure-activity relationship study. Xu T; Yang J; Li D; Challa M; Zou C; Deng P; Zhang SL; Xu B Eur J Med Chem; 2024 Sep; 275():116610. PubMed ID: 38896992 [TBL] [Abstract][Full Text] [Related]
15. Biochemical, cellular, and biophysical characterization of a potent inhibitor of mutant isocitrate dehydrogenase IDH1. Davis MI; Gross S; Shen M; Straley KS; Pragani R; Lea WA; Popovici-Muller J; DeLaBarre B; Artin E; Thorne N; Auld DS; Li Z; Dang L; Boxer MB; Simeonov A J Biol Chem; 2014 May; 289(20):13717-25. PubMed ID: 24668804 [TBL] [Abstract][Full Text] [Related]
16. Discovery of a Novel Chemical Scaffold Against Mutant Isocitrate Dehydrogenase 1 (IDH1). Kang CH; Choi SU; Son YH; Lee HK; Jeong HG; Yun CS; Ahn S; Park CH Anticancer Res; 2020 Sep; 40(9):4929-4935. PubMed ID: 32878781 [TBL] [Abstract][Full Text] [Related]
17. Identification of novel allosteric inhibitors of mutant isocitrate dehydrogenase 1 by cross docking-based virtual screening. Zou F; Pusch S; Hua J; Ma T; Yang L; Zhu Q; Xu Y; Gu Y; von Deimling A; Zha X Bioorg Med Chem Lett; 2018 Feb; 28(3):388-393. PubMed ID: 29290542 [TBL] [Abstract][Full Text] [Related]
18. Design and synthesis of novel 2-arylbenzimidazoles as selective mutant isocitrate dehydrogenase 2 R140Q inhibitors. Li Z; Wu X; Jia L; Li J; Zhang R; Tang H; Li Z; Bu H; Shen C Bioorg Med Chem Lett; 2020 May; 30(9):127070. PubMed ID: 32143887 [TBL] [Abstract][Full Text] [Related]
19. Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. Deng G; Shen J; Yin M; McManus J; Mathieu M; Gee P; He T; Shi C; Bedel O; McLean LR; Le-Strat F; Zhang Y; Marquette JP; Gao Q; Zhang B; Rak A; Hoffmann D; Rooney E; Vassort A; Englaro W; Li Y; Patel V; Adrian F; Gross S; Wiederschain D; Cheng H; Licht S J Biol Chem; 2015 Jan; 290(2):762-74. PubMed ID: 25391653 [TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, and evaluation of 3-aryl-4-pyrrolyl-maleimides as glycogen synthase kinase-3β inhibitors. Ye Q; Li M; Zhou YB; Cao JY; Xu L; Li YJ; Han L; Gao JR; Hu YZ; Li J Arch Pharm (Weinheim); 2013 May; 346(5):349-58. PubMed ID: 23585245 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]