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2. FDA Approval: Gemtuzumab Ozogamicin for the Treatment of Adults with Newly Diagnosed CD33-Positive Acute Myeloid Leukemia. Jen EY; Ko CW; Lee JE; Del Valle PL; Aydanian A; Jewell C; Norsworthy KJ; Przepiorka D; Nie L; Liu J; Sheth CM; Shapiro M; Farrell AT; Pazdur R Clin Cancer Res; 2018 Jul; 24(14):3242-3246. PubMed ID: 29476018 [TBL] [Abstract][Full Text] [Related]
3. Expression and functional characterization of CD33 transcript variants in human acute myeloid leukemia. Laszlo GS; Harrington KH; Gudgeon CJ; Beddoe ME; Fitzgibbon MP; Ries RE; Lamba JK; McIntosh MW; Meshinchi S; Walter RB Oncotarget; 2016 Jul; 7(28):43281-43294. PubMed ID: 27248327 [TBL] [Abstract][Full Text] [Related]
4. CD33 Splicing Polymorphism Determines Gemtuzumab Ozogamicin Response in De Novo Acute Myeloid Leukemia: Report From Randomized Phase III Children's Oncology Group Trial AAML0531. Lamba JK; Chauhan L; Shin M; Loken MR; Pollard JA; Wang YC; Ries RE; Aplenc R; Hirsch BA; Raimondi SC; Walter RB; Bernstein ID; Gamis AS; Alonzo TA; Meshinchi S J Clin Oncol; 2017 Aug; 35(23):2674-2682. PubMed ID: 28644774 [TBL] [Abstract][Full Text] [Related]
5. Cellular determinants for preclinical activity of a novel CD33/CD3 bispecific T-cell engager (BiTE) antibody, AMG 330, against human AML. Laszlo GS; Gudgeon CJ; Harrington KH; Dell'Aringa J; Newhall KJ; Means GD; Sinclair AM; Kischel R; Frankel SR; Walter RB Blood; 2014 Jan; 123(4):554-61. PubMed ID: 24311721 [TBL] [Abstract][Full Text] [Related]
6. No evidence that CD33 splicing SNP impacts the response to GO in younger adults with AML treated on UK MRC/NCRI trials. Gale RE; Popa T; Wright M; Khan N; Freeman SD; Burnett AK; Russell NH; Hills RK; Linch DC Blood; 2018 Jan; 131(4):468-471. PubMed ID: 29229596 [No Abstract] [Full Text] [Related]
7. MDSC targeting with Gemtuzumab ozogamicin restores T cell immunity and immunotherapy against cancers. Fultang L; Panetti S; Ng M; Collins P; Graef S; Rizkalla N; Booth S; Lenton R; Noyvert B; Shannon-Lowe C; Middleton G; Mussai F; De Santo C EBioMedicine; 2019 Sep; 47():235-246. PubMed ID: 31462392 [TBL] [Abstract][Full Text] [Related]
8. The Broad Anti-AML Activity of the CD33/CD3 BiTE Antibody Construct, AMG 330, Is Impacted by Disease Stage and Risk. Harrington KH; Gudgeon CJ; Laszlo GS; Newhall KJ; Sinclair AM; Frankel SR; Kischel R; Chen G; Walter RB PLoS One; 2015; 10(8):e0135945. PubMed ID: 26305211 [TBL] [Abstract][Full Text] [Related]
10. CRISPR/Cas9 gene editing clarifies the role of CD33 SNP rs12459419 in gemtuzumab ozogamicin-mediated cytotoxicity. Oya S; Ozawa H; Nakamura T; Mori A; Ochi S; Maehiro Y; Umeda M; Takaki Y; Fukuyama T; Yamasaki Y; Yamaguchi M; Aoyama K; Mouri F; Nagafuji K Int J Hematol; 2024 Aug; 120(2):194-202. PubMed ID: 38853211 [TBL] [Abstract][Full Text] [Related]
11. T cell engaging bispecific antibodies targeting CD33 IgV and IgC domains for the treatment of acute myeloid leukemia. Hoseini SS; Vadlamudi M; Espinosa-Cotton M; Tran H; Feng Y; Guo HF; Xu H; Cheung I; Cheung NV J Immunother Cancer; 2021 May; 9(5):. PubMed ID: 34035113 [TBL] [Abstract][Full Text] [Related]
12. Time to reconsider CD33 single nucleotide polymorphism in the response to gemtuzumab ozogamicin. Lamba JK; Meshinchi S Haematologica; 2021 Nov; 106(11):2796-2798. PubMed ID: 34092060 [No Abstract] [Full Text] [Related]
13. T-cell ligands modulate the cytolytic activity of the CD33/CD3 BiTE antibody construct, AMG 330. Laszlo GS; Gudgeon CJ; Harrington KH; Walter RB Blood Cancer J; 2015 Aug; 5(8):e340. PubMed ID: 26295610 [TBL] [Abstract][Full Text] [Related]
14. IMGN779, a Novel CD33-Targeting Antibody-Drug Conjugate with DNA-Alkylating Activity, Exhibits Potent Antitumor Activity in Models of AML. Kovtun Y; Noordhuis P; Whiteman KR; Watkins K; Jones GE; Harvey L; Lai KC; Portwood S; Adams S; Sloss CM; Schuurhuis GJ; Ossenkoppele G; Wang ES; Pinkas J Mol Cancer Ther; 2018 Jun; 17(6):1271-1279. PubMed ID: 29588393 [TBL] [Abstract][Full Text] [Related]
15. Characterization of CD33/CD3 Tetravalent Bispecific Tandem Diabodies (TandAbs) for the Treatment of Acute Myeloid Leukemia. Reusch U; Harrington KH; Gudgeon CJ; Fucek I; Ellwanger K; Weichel M; Knackmuss SH; Zhukovsky EA; Fox JA; Kunkel LA; Guenot J; Walter RB Clin Cancer Res; 2016 Dec; 22(23):5829-5838. PubMed ID: 27189165 [TBL] [Abstract][Full Text] [Related]
16. CD33 target validation and sustained depletion of AML blasts in long-term cultures by the bispecific T-cell-engaging antibody AMG 330. Krupka C; Kufer P; Kischel R; Zugmaier G; Bögeholz J; Köhnke T; Lichtenegger FS; Schneider S; Metzeler KH; Fiegl M; Spiekermann K; Baeuerle PA; Hiddemann W; Riethmüller G; Subklewe M Blood; 2014 Jan; 123(3):356-65. PubMed ID: 24300852 [TBL] [Abstract][Full Text] [Related]
17. CD33 splice site genotype was not associated with outcomes of patients receiving the anti-CD33 drug conjugate SGN-CD33A. Stanchina M; Pastore A; Devlin S; Famulare C; Stein E; Taylor J J Hematol Oncol; 2019 Aug; 12(1):85. PubMed ID: 31439003 [TBL] [Abstract][Full Text] [Related]
18. Impact of CD33 and ABCB1 single nucleotide polymorphisms in patients with acute myeloid leukemia and advanced myeloid malignancies treated with decitabine plus gemtuzumab ozogamicin. Short NJ; Richard-Carpentier G; Kanagal-Shamanna R; Patel KP; Konopleva M; Papageorgiou I; Pemmaraju N; Borthakur G; Ravandi F; DiNardo CD; Kadia TM; Kantarjian H; Lamba JK; Daver N Am J Hematol; 2020 Sep; 95(9):E225-E228. PubMed ID: 32356320 [No Abstract] [Full Text] [Related]
19. Blockade of the PD-1/PD-L1 axis augments lysis of AML cells by the CD33/CD3 BiTE antibody construct AMG 330: reversing a T-cell-induced immune escape mechanism. Krupka C; Kufer P; Kischel R; Zugmaier G; Lichtenegger FS; Köhnke T; Vick B; Jeremias I; Metzeler KH; Altmann T; Schneider S; Fiegl M; Spiekermann K; Bauerle PA; Hiddemann W; Riethmüller G; Subklewe M Leukemia; 2016 Feb; 30(2):484-91. PubMed ID: 26239198 [TBL] [Abstract][Full Text] [Related]
20. FDA Approval Summary: Mylotarg for Treatment of Patients with Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia. Norsworthy KJ; Ko CW; Lee JE; Liu J; John CS; Przepiorka D; Farrell AT; Pazdur R Oncologist; 2018 Sep; 23(9):1103-1108. PubMed ID: 29650683 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]