BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 30120199)

  • 21. Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD.
    Khosravi B; LaClair KD; Riemenschneider H; Zhou Q; Frottin F; Mareljic N; Czuppa M; Farny D; Hartmann H; Michaelsen M; Arzberger T; Hartl FU; Hipp MS; Edbauer D
    EMBO J; 2020 Apr; 39(8):e102811. PubMed ID: 32175624
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP-43.
    Urushitani M; Sato T; Bamba H; Hisa Y; Tooyama I
    J Neurosci Res; 2010 Mar; 88(4):784-97. PubMed ID: 19798749
    [TBL] [Abstract][Full Text] [Related]  

  • 23. TDP-43 and FUS en route from the nucleus to the cytoplasm.
    Ederle H; Dormann D
    FEBS Lett; 2017 Jun; 591(11):1489-1507. PubMed ID: 28380257
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Overexpression of heat shock factor 1 maintains TAR DNA binding protein 43 solubility via induction of inducible heat shock protein 70 in cultured cells.
    Lin PY; Folorunso O; Taglialatela G; Pierce A
    J Neurosci Res; 2016 Jul; 94(7):671-82. PubMed ID: 26994698
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Mass spectrometric analysis of accumulated TDP-43 in amyotrophic lateral sclerosis brains.
    Kametani F; Obi T; Shishido T; Akatsu H; Murayama S; Saito Y; Yoshida M; Hasegawa M
    Sci Rep; 2016 Mar; 6():23281. PubMed ID: 26980269
    [TBL] [Abstract][Full Text] [Related]  

  • 26. PABPN1 suppresses TDP-43 toxicity in ALS disease models.
    Chou CC; Alexeeva OM; Yamada S; Pribadi A; Zhang Y; Mo B; Williams KR; Zarnescu DC; Rossoll W
    Hum Mol Genet; 2015 Sep; 24(18):5154-73. PubMed ID: 26130692
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination.
    Dammer EB; Fallini C; Gozal YM; Duong DM; Rossoll W; Xu P; Lah JJ; Levey AI; Peng J; Bassell GJ; Seyfried NT
    PLoS One; 2012; 7(6):e38658. PubMed ID: 22761693
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Conserved acidic amino acid residues in a second RNA recognition motif regulate assembly and function of TDP-43.
    Shodai A; Ido A; Fujiwara N; Ayaki T; Morimura T; Oono M; Uchida T; Takahashi R; Ito H; Urushitani M
    PLoS One; 2012; 7(12):e52776. PubMed ID: 23300771
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Regulation of TDP-43 aggregation by phosphorylation and p62/SQSTM1.
    Brady OA; Meng P; Zheng Y; Mao Y; Hu F
    J Neurochem; 2011 Jan; 116(2):248-59. PubMed ID: 21062285
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.
    Gruijs da Silva LA; Simonetti F; Hutten S; Riemenschneider H; Sternburg EL; Pietrek LM; Gebel J; Dötsch V; Edbauer D; Hummer G; Stelzl LS; Dormann D
    EMBO J; 2022 Apr; 41(8):e108443. PubMed ID: 35112738
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells.
    Nonaka T; Arai T; Buratti E; Baralle FE; Akiyama H; Hasegawa M
    FEBS Lett; 2009 Jan; 583(2):394-400. PubMed ID: 19111550
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Different aggregation states of a nuclear localization signal-tagged 25-kDa C-terminal fragment of TAR RNA/DNA-binding protein 43 kDa.
    Kitamura A; Yuno S; Muto H; Kinjo M
    Genes Cells; 2017 Jun; 22(6):521-534. PubMed ID: 28497562
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Differential toxicity of TAR DNA-binding protein 43 isoforms depends on their submitochondrial localization in neuronal cells.
    Salvatori I; Ferri A; Scaricamazza S; Giovannelli I; Serrano A; Rossi S; D'Ambrosi N; Cozzolino M; Giulio AD; Moreno S; Valle C; Carrì MT
    J Neurochem; 2018 Sep; 146(5):585-597. PubMed ID: 29779213
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Phosphorylation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Truncated Casein Kinase 1δ Triggers Mislocalization and Accumulation of TDP-43.
    Nonaka T; Suzuki G; Tanaka Y; Kametani F; Hirai S; Okado H; Miyashita T; Saitoe M; Akiyama H; Masai H; Hasegawa M
    J Biol Chem; 2016 Mar; 291(11):5473-5483. PubMed ID: 26769969
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy.
    Arai T; Hasegawa M; Nonoka T; Kametani F; Yamashita M; Hosokawa M; Niizato K; Tsuchiya K; Kobayashi Z; Ikeda K; Yoshida M; Onaya M; Fujishiro H; Akiyama H
    Neuropathology; 2010 Apr; 30(2):170-81. PubMed ID: 20102522
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
    Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
    Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Templated Aggregation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Seeding with TDP-43 Peptide Fibrils.
    Shimonaka S; Nonaka T; Suzuki G; Hisanaga S; Hasegawa M
    J Biol Chem; 2016 Apr; 291(17):8896-907. PubMed ID: 26887947
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43.
    Nonaka T; Kametani F; Arai T; Akiyama H; Hasegawa M
    Hum Mol Genet; 2009 Sep; 18(18):3353-64. PubMed ID: 19515851
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Small Molecule Targeting TDP-43's RNA Recognition Motifs Reduces Locomotor Defects in a
    François-Moutal L; Felemban R; Scott DD; Sayegh MR; Miranda VG; Perez-Miller S; Khanna R; Gokhale V; Zarnescu DC; Khanna M
    ACS Chem Biol; 2019 Sep; 14(9):2006-2013. PubMed ID: 31241884
    [TBL] [Abstract][Full Text] [Related]  

  • 40. [The molecular mechanisms of intracellular TDP-43 aggregates].
    Nonaka T; Arai T; Hasegawa M
    Brain Nerve; 2009 Nov; 61(11):1292-300. PubMed ID: 19938686
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.