BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 30120879)

  • 1. Design, synthesis, and biological evaluation of 2-(4-(methylsulfonyl)phenyl)pyridine derivatives as GPR119 agonists.
    Zhou Y; Zhu X; Zhang L; Tang C; Feng B
    Chem Biol Drug Des; 2019 Jan; 93(1):67-74. PubMed ID: 30120879
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and evaluation of a series of novel phenylpropanoic acid derivatives agonists for the FFA1.
    Yang J; Gu E; Yan T; Shen D; Feng B; Tang C
    Chem Biol Drug Des; 2019 May; 93(5):900-909. PubMed ID: 30657643
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and biological evaluation of novel 7-azaspiro[3.5]nonane derivatives as GPR119 agonists.
    Matsuda D; Kawamura M; Kobashi Y; Shiozawa F; Suga Y; Fusegi K; Nishimoto S; Kimura K; Miyoshi M; Takayama N; Kakinuma H; Ohtake N
    Bioorg Med Chem; 2018 May; 26(8):1832-1847. PubMed ID: 29486951
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and biological evaluation of tetrahydropyridine derivatives as novel human GPR119 agonists.
    Zuo Z; Chen M; Shao X; Qian X; Liu X; Zhou X; Xiang J; Deng P; Li Y; Jie H; Liu C; Cen X; Xie Y; Zhao Y
    Bioorg Med Chem Lett; 2020 Feb; 30(4):126855. PubMed ID: 31898998
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of 1, 2, 4-oxadiazole derivatives as novel GPR119 agonists.
    Fu S; Xiang W; Chen J; Ma L; Chen L
    Chem Biol Drug Des; 2017 May; 89(5):815-819. PubMed ID: 27779815
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery and biological evaluation of novel G protein-coupled receptor 119 agonists for type 2 diabetes.
    Zhou Y; Wang Y; Zhang L; Tang C; Feng B
    Arch Pharm (Weinheim); 2019 Apr; 352(4):e1800267. PubMed ID: 30740769
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel GPR119 agonist DA-1241 preserves pancreatic function via the suppression of ER stress and increased PDX1 expression.
    Kim MK; Cheong YH; Lee SH; Kim TH; Jung IH; Chae Y; Lee JH; Yang EK; Park H; Yang JS; Hong KW
    Biomed Pharmacother; 2021 Dec; 144():112324. PubMed ID: 34678732
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and synthesis of tetrahydropyridopyrimidine derivatives as dual GPR119 and DPP-4 modulators.
    Fang Y; Zhang S; Wu W; Liu Y; Yang J; Li Y; Li M; Dong H; Jin Y; Liu R; Yang Z
    Bioorg Chem; 2020 Jan; 94():103390. PubMed ID: 31662212
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of novel selective GPR120 agonists with potent anti-diabetic activity by hybrid design.
    Sheng R; Yang L; Zhang Y; Xing E; Shi R; Wen X; Wang H; Sun H
    Bioorg Med Chem Lett; 2018 Aug; 28(15):2599-2604. PubMed ID: 29980358
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and synthesis of novel pyrimido[5,4-d]pyrimidine derivatives as GPR119 agonist for treatment of type 2 diabetes.
    Fang Y; Xu J; Li Z; Yang Z; Xiong L; Jin Y; Wang Q; Xie S; Zhu W; Chang S
    Bioorg Med Chem; 2018 Aug; 26(14):4080-4087. PubMed ID: 30100020
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and biological evaluation of aryl N-methoxyamide derivatives as GPR119 agonists.
    Jang YK; Lee KM; Jung KY; Kang SK; Pagire SH; Lee JM; Pagire HS; Kim KR; Bae MA; Lee H; Rhee SD; Ahn JH
    Bioorg Med Chem Lett; 2017 Aug; 27(16):3909-3914. PubMed ID: 28666737
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery and biological evaluation of novel 4-amino-2-phenylpyrimidine derivatives as potent and orally active GPR119 agonists.
    Negoro K; Yonetoku Y; Misawa-Mukai H; Hamaguchi W; Maruyama T; Yoshida S; Takeuchi M; Ohta M
    Bioorg Med Chem; 2012 Sep; 20(17):5235-46. PubMed ID: 22836190
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and synthesis of novel and potent GPR119 agonists with a spirocyclic structure.
    Harada K; Mizukami J; Kadowaki S; Matsuda I; Watanabe T; Oe Y; Kodama Y; Aoki K; Suwa K; Fukuda S; Yata S; Inaba T
    Bioorg Med Chem Lett; 2018 Apr; 28(7):1228-1233. PubMed ID: 29519733
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and SAR studies of bicyclic amine series GPR119 agonists.
    Sakairi M; Kogami M; Torii M; Kataoka H; Fujieda H; Makino M; Kataoka D; Okamoto R; Miyazawa T; Okabe M; Inoue M; Takahashi N; Harada S; Watanabe N
    Bioorg Med Chem Lett; 2012 Aug; 22(15):5123-8. PubMed ID: 22765901
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery, optimisation and in vivo evaluation of novel GPR119 agonists.
    Brocklehurst KJ; Broo A; Butlin RJ; Brown HS; Clarke DS; Davidsson Ö; Goldberg K; Groombridge SD; Kelly EE; Leach A; McKerrecher D; O'Donnell C; Poucher S; Schofield P; Scott JS; Teague J; Westgate L; Wood MJ
    Bioorg Med Chem Lett; 2011 Dec; 21(24):7310-6. PubMed ID: 22061639
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel GPR119 agonist HD0471042 attenuated type 2 diabetes mellitus.
    Ha TY; Kim YS; Kim CH; Choi HS; Yang J; Park SH; Kim DH; Rhee JK
    Arch Pharm Res; 2014 May; 37(5):671-8. PubMed ID: 23897163
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and biological evaluation of a novel class of potent TGR5 agonists based on a 4-phenyl pyridine scaffold.
    Zhu J; Ning M; Guo C; Zhang L; Pan G; Leng Y; Shen J
    Eur J Med Chem; 2013 Nov; 69():55-68. PubMed ID: 24007860
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Optimisation of novel 4, 8-disubstituted dihydropyrimido[5,4-
    Fang Y; Zhang S; Li M; Xiong L; Tu L; Xie S; Jin Y; Liu Y; Yang Z; Liu R
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):50-58. PubMed ID: 31656107
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and biological activity of phenoxyacetic acid derivatives as novel free fatty acid receptor 1 agonists.
    Li Z; Wang X; Xu X; Yang J; Xia W; Zhou X; Huang W; Qian H
    Bioorg Med Chem; 2015 Nov; 23(22):7158-64. PubMed ID: 26482570
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of thienopyrimidine derivatives as GPR119 agonists.
    Jeon MK; Lee KM; Kim IH; Jang YK; Kang SK; Lee JM; Jung KY; Kumar JA; Rhee SD; Jung WH; Song JS; Bae MA; Kim KR; Ahn JH
    Bioorg Med Chem Lett; 2014 Sep; 24(17):4281-5. PubMed ID: 25082125
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.